PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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4DO5	Pharmacological chaperones for human alpha-N-acetylgalactosaminidase 分子名称: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Clark, N.E, Garman, S.C. 登録日 2012-02-09 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Pharmacological chaperones for human alpha-N-acetylgalactosaminidase Proc.Natl.Acad.Sci.USA, 109, 2012
4DR1	Crystal structure of the apo 30S ribosomal subunit from Thermus thermophilus (HB8) 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-16 公開日 2012-11-14 最終更新日 2013-01-30 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
4DQG	Crystal Structure of apo(G16C/L38C) HIV-1 Protease 分子名称: ACETATE ION, Aspartyl protease, GLYCEROL, ... 著者 Schiffer, C.A, Mittal, S. 登録日 2012-02-15 公開日 2012-03-07 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease. J.Am.Chem.Soc., 134, 2012
4DQP	Ternary complex of Bacillus DNA Polymerase I Large Fragment, DNA duplex, and ddCTP (paired with dG of template) 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*C*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... 著者 Wang, W, Beese, L.S. 登録日 2012-02-16 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. J.Biol.Chem., 287, 2012
4DVK	Crystal structure of the glycoprotein Erns from the pestivirus BVDV-1 strain NCP-7 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E(rns) glycoprotein, ... 著者 Krey, T, Bontems, F, Vonrhein, C, Vaney, M.-C, Bricogne, G, Ruemenapf, T, Rey, F.A. 登録日 2012-02-23 公開日 2012-05-23 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. Structure, 20, 2012
4DVR	Crystal structure of YU2 gp120 core in complex with Fab 48d and NBD-557 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, Fab 48d Heavy chain, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2012-02-23 公開日 2013-02-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site. Plos One, 9, 2014
4DRI	Co-crystal structure of the PPIase domain of FKBP51, Rapamycin and the FRB fragment of mTOR 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, Serine/threonine-protein kinase mTOR 著者 Maerz, A.M, Bracher, A, Hausch, F. 登録日 2012-02-17 公開日 2013-02-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin. Mol.Cell.Biol., 33, 2013
4DRP	Evaluation of Synthetic FK506 Analogs as Ligands for the FK506-Binding Proteins 51 and 52: Complex of FKBP51 with 2-(3-((R)-3-(3,4-dimethoxyphenyl)-1-((S)-1-(2-((1R,2S)-2-ethyl-1-hydroxy-cyclohexyl)-2-oxoacetyl)piperidine-2-carbonyloxy)propyl)phenoxy)acetic acid from cocrystallization 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, {3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-{[(1R,2S)-2-ethyl-1-hydroxycyclohexyl](oxo)acetyl}piperidin-2-yl]carbonyl}oxy)propyl]phenoxy}acetic acid 著者 Gopalakrishnan, R, Kozany, C, Gaali, S, Kress, C, Hoogeland, B, Bracher, A, Hausch, F. 登録日 2012-02-17 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52. J.Med.Chem., 55, 2012
4DW8	Crystal structure of a haloacid dehalogenase-like hydrolase (Target EFI-900331) from Bacteroides thetaiotaomicron with bound Na crystal form I 分子名称: Haloacid dehalogenase-like hydrolase, SODIUM ION, UNKNOWN LIGAND 著者 Vetting, M.W, Wasserman, S.R, Morisco, L.L, Sojitra, S, Allen, K.N, Dunaway-Mariano, D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2012-02-24 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.502 Å) 主引用文献 Crystal structure of a haloacid dehalogenase-like hydrolase (Target EFI-900331) from Bacteroides thetaiotaomicron with bound Na crystal form I To be Published
4DWE	Crystal structure of a putative polysaccharide deacetylase (BACOVA_03992) from Bacteroides ovatus ATCC 8483 at 2.01 A resolution 分子名称: GLYCEROL, uncharacterized protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2012-02-24 公開日 2012-05-02 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystal structure of a hypothetical protein (BACOVA_03992) from Bacteroides ovatus ATCC 8483 at 2.01 A resolution To be published
4DS2	Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi 分子名称: Ubiquitin-conjugating enzyme E2, putative 著者 Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) 登録日 2012-02-17 公開日 2012-02-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi To be Published
4DWS	Crystal Structure of a chitinase from the Yersinia entomophaga toxin complex 分子名称: Chi2, GLYCEROL 著者 Busby, J.N, Hurst, M.R.H, Lott, J.S. 登録日 2012-02-26 公開日 2013-02-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device. Nature, 501, 2013
4DSE	Ternary complex of Bacillus DNA Polymerase I Large Fragment F710Y, DNA duplex, and rCTP (paired with dG of template) in presence of Mg2+ 分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... 著者 Wang, W, Beese, L.S. 登録日 2012-02-18 公開日 2012-06-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. J.Biol.Chem., 287, 2012
4DT5	Crystal Structure of Rhagium inquisitor Antifreeze Protein 分子名称: Antifreeze protein, GLYCEROL, SULFATE ION 著者 Meng, W, Nguyen, J.B, Hakim, A, Thakral, D, Zhu, D.F. 登録日 2012-02-20 公開日 2013-03-13 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Crystal structure of an insect antifreeze protein and its implications for ice binding. J.Biol.Chem., 288, 2013
4DYT	Crystal Structure of WSN/A Influenza Nucleoprotein with Three Mutations (E53D, Y289H, Y313V) 分子名称: Nucleocapsid protein 著者 Lewis, H.A, Baldwin, E.T, Steinbacher, S, Maskos, K, Mortl, M, Kiefersauer, R, Edavettal, S, McDonnell, P.A, Pearce, B.C, Langley, D.R. 登録日 2012-02-29 公開日 2013-03-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 To be determined To be Published
4DV3	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, C912A, bound with streptomycin 分子名称: 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-22 公開日 2013-02-27 実験手法 X-RAY DIFFRACTION (3.547 Å) 主引用文献 A structural basis for streptomycin resistance To be Published
4E3E	CRYSTAL STRUCTURE OF putative MaoC domain protein dehydratase from Chloroflexus aurantiacus J-10-fl 分子名称: MaoC domain protein dehydratase, SULFATE ION 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Zenchek, W, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2012-03-09 公開日 2012-03-21 最終更新日 2012-05-02 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 CRYSTAL STRUCTURE OF putative MaoC domain protein dehydratase from Chloroflexus aurantiacus J-10-fl To be Published
4DX1	Crystal structure of the human TRPV4 ankyrin repeat domain 分子名称: GLYCEROL, PHOSPHATE ION, Transient receptor potential cation channel subfamily V member 4 著者 Inada, H, Gaudet, R. 登録日 2012-02-27 公開日 2012-07-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel. Biochemistry, 51, 2012
4DA7	Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with aciclovir 分子名称: 9-HYROXYETHOXYMETHYLGUANINE, PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type 著者 Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. 登録日 2012-01-12 公開日 2012-09-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
4DAC	Crystal Structure of Computationally Designed Protein P6d 分子名称: Computationally designed crystal forming protein P6d 著者 Lanci, C.J, MacDermaid, C.M, Saven, J.G. 登録日 2012-01-12 公開日 2012-05-02 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Computational design of a protein crystal. Proc.Natl.Acad.Sci.USA, 109, 2012
4DAL	Crystal structure of Putative aldehyde dehydrogenase from Sinorhizobium meliloti 1021 分子名称: GLYCEROL, Putative aldehyde dehydrogenase 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2012-01-12 公開日 2012-03-14 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of Putative aldehyde dehydrogenase from Sinorhizobium meliloti 1021 To be Published
4DDY	CTX-M-9 class A beta-lactamase complexed with compound 10 分子名称: Beta-lactamase, DIMETHYL SULFOXIDE, N-[3-(1H-tetrazol-5-yl)phenyl]-3-(trifluoromethyl)benzamide 著者 Nichols, D.A, Chen, Y. 登録日 2012-01-19 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Structure-Based Design of Potent and Ligand-Efficient Inhibitors of CTX-M Class A Beta-Lactamase J.Med.Chem., 55, 2012
4DFL	Crystal structure of spleen tyrosine kinase complexed with a sulfonamidopyrazine piperidine inhibitor 分子名称: 1,2-ETHANEDIOL, 3-amino-6-{3-[(methylsulfonyl)amino]phenyl}-N-(piperidin-4-ylmethyl)pyrazine-2-carboxamide, SULFATE ION, ... 著者 Lopez, M, Segarra, V, Vidal, B, Wenzkowski, C, Jestel, A, Krapp, S, Blaesse, M, Nagel, S, Schreiner, P. 登録日 2012-01-24 公開日 2012-04-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Pyrazine-based Syk kinase inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
4DYX	Crystal Structure of the Cu-adduct of Human H-Ferritin variant 4His-delta C-star 分子名称: CALCIUM ION, COPPER (II) ION, Ferritin heavy chain 著者 Tezcan, F.A, Huard, D.J.E. 登録日 2012-02-29 公開日 2013-01-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Re-engineering protein interfaces yields copper-inducible ferritin cage assembly. Nat.Chem.Biol., 9, 2013
4DGE	TRIMCyp cyclophilin domain from Macaca mulatta: H70C mutant, HIV-1 CA(O-loop) complex 分子名称: TRIMCyp, capsid protein 著者 Caines, M.E.C, Bichel, K, Price, A.J, McEwan, W.A, James, L.C. 登録日 2012-01-25 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Diverse HIV viruses are targeted by a conformationally dynamic antiviral. Nat.Struct.Mol.Biol., 19, 2012

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