4DVR

Crystal structure of YU2 gp120 core in complex with Fab 48d and NBD-557

Summary for 4DVR

• Entry DOI: 10.2210/pdb4dvr/pdb
• Descriptor: Envelope glycoprotein gp120, Fab 48d Light chain, Fab 48d Heavy chain, ... (6 entities in total)
• Functional Keywords: hiv-1 gp120, cd4 binding site, nbd-557, immune system-transcription inhibitor complex, immune system/transcription inhibitor
• Biological source: Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1); More
• Total number of polymer chains: 3
• Total formula weight: 83328.08

Authors

Kwon, Y.D.,Kwong, P.D. (deposition date: 2012-02-23, release date: 2013-02-27, Last modification date: 2023-09-13)

• Primary citation: Kwon, Y.D.,Lalonde, J.M.,Yang, Y.,Elban, M.A.,Sugawara, A.,Courter, J.R.,Jones, D.M.,Smith, A.B.,Debnath, A.K.,Kwong, P.D.; Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site.; Plos One, 9:e85940-e85940, 2014; PubMed: 24489681; DOI: 10.1371/journal.pone.0085940

Experimental method

X-RAY DIFFRACTION (2.5 Å)