4DVR
Crystal structure of YU2 gp120 core in complex with Fab 48d and NBD-557
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | G | Envelope glycoprotein gp120 | polymer | 313 | 34918.6 | 1 | UniProt (P35961) Pfam (PF00516) In PDB | Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) (HIV-1) | Env polyprotein,Env polyprotein,Env polyprotein |
2 | L | Fab 48d Light chain | polymer | 212 | 23092.6 | 1 | Homo sapiens (human) | ||
3 | H | Fab 48d Heavy chain | polymer | 219 | 23386.1 | 1 | Homo sapiens (human) | ||
4 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
5 | G | N-(4-bromophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)ethanediamide | non-polymer | 382.3 | 1 | Chemie (0LY) | |||
6 | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence modifications
G: 83 - 123 (UniProt: P35961)
G: 199 - 301 (UniProt: P35961)
G: 324 - 492 (UniProt: P35961)
G: 199 - 301 (UniProt: P35961)
PDB | External Database | Details |
---|---|---|
Gly 124 | - | linker |
Gly 198 | - | linker |
PDB | External Database | Details |
---|---|---|
Gly 318 | - | linker |
Gly 319 | - | linker |
Ser 320 | - | linker |
Gly 321 | - | linker |
Ser 322 | - | linker |
Gly 323 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 81397.3 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1930.8 | |
All* | Total formula weight | 83328.1 |