8P4D
| Structural insights into human co-transcriptional capping - structure 4 | 分子名称: | DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... | 著者 | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | 登録日 | 2023-05-20 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
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8P4B
| Structural insights into human co-transcriptional capping - structure 2 | 分子名称: | DNA (35-MER), DNA (5'-D(P*AP*GP*CP*GP*GP*CP*GP*GP*AP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*AP*GP*CP*TP*G)-3'), DNA-directed RNA polymerase II subunit E, ... | 著者 | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | 登録日 | 2023-05-20 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
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8P4C
| Structural insights into human co-transcriptional capping - structure 3 | 分子名称: | DNA (32-MER), DNA (41-MER), DNA-directed RNA polymerase II subunit E, ... | 著者 | Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P. | 登録日 | 2023-05-20 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural insights into human co-transcriptional capping. Mol.Cell, 83, 2023
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8P1J
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8P1N
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8P1L
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8P1K
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8P1M
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8JCH
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8P0B
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8P0U
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8P0G
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8SQ9
| SARS-CoV-2 replication-transcription complex bound to nsp9 and UMPCPP, as a pre-catalytic NMPylation intermediate | 分子名称: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]uridine, MAGNESIUM ION, Non-structural protein 7, ... | 著者 | Small, G.I, Darst, S.A, Campbell, E.A. | 登録日 | 2023-05-04 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain. Mol.Cell, 83, 2023
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8SQJ
| SARS-CoV-2 replication-transcription complex bound to RNA-nsp9, as a noncatalytic RNA-nsp9 binding mode | 分子名称: | 5'-O-[(R)-hydroxy(thiophosphonooxy)phosphoryl]guanosine, MAGNESIUM ION, Non-structural protein 7, ... | 著者 | Small, G.I, Darst, S.A, Campbell, E.A. | 登録日 | 2023-05-04 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain. Mol.Cell, 83, 2023
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8SQK
| SARS-CoV-2 replication-transcription complex bound to RNA-nsp9 and GDP-betaS, as a pre-catalytic deRNAylation/mRNA capping intermediate | 分子名称: | 5'-O-[(R)-hydroxy(thiophosphonooxy)phosphoryl]guanosine, MAGNESIUM ION, Non-structural protein 7, ... | 著者 | Small, G.I, Darst, S.A, Campbell, E.A. | 登録日 | 2023-05-04 | 公開日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain. Mol.Cell, 83, 2023
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8SNX
| Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) bound to the leader promoter | 分子名称: | Phosphoprotein, RNA (5'-R(*UP*UP*UP*UP*UP*CP*GP*CP*GP*U)-3'), RNA-directed RNA polymerase L | 著者 | Cao, D, Gao, Y, Chen, Z, Gooneratne, I, Roesler, C, Mera, C, Liang, B. | 登録日 | 2023-04-28 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of the promoter-bound respiratory syncytial virus polymerase. Nature, 625, 2024
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8SNY
| Cryo-EM structure of the respiratory syncytial virus polymerase (L:P) bound to the trailer complementary promoter | 分子名称: | Phosphoprotein, RNA (5'-R(*UP*UP*UP*UP*UP*CP*UP*CP*GP*U)-3'), RNA-directed RNA polymerase L | 著者 | Cao, D, Gao, Y, Chen, Z, Gooneratne, I, Roesler, C, Mera, C, Liang, B. | 登録日 | 2023-04-28 | 公開日 | 2023-12-20 | 最終更新日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Structures of the promoter-bound respiratory syncytial virus polymerase. Nature, 625, 2024
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8IZM
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8IZL
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8OEV
| Structure of the mammalian Pol II-SPT6-Elongin complex, lacking ELOA latch (composite structure, structure 3) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | 登録日 | 2023-03-13 | 公開日 | 2023-10-18 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
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8OEU
| Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | 登録日 | 2023-03-13 | 公開日 | 2023-10-18 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
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8OF0
| Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | 登録日 | 2023-03-13 | 公開日 | 2023-10-18 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
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8OEW
| Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite structure, structure 2) | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P. | 登録日 | 2023-03-13 | 公開日 | 2023-10-18 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure of the transcribing RNA polymerase II-Elongin complex. Nat.Struct.Mol.Biol., 30, 2023
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8IIB
| Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546) | 分子名称: | CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Fang, X, Lu, G, Hou, C, Gong, P. | 登録日 | 2023-02-24 | 公開日 | 2023-06-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding. Virol Sin, 38, 2023
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8IIC
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