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7Y3A
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Crystal structure of TRIM7 bound to 2C
分子名称: E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,E3 ubiquitin-protein ligase TRIM7,TRIM7-2C
著者Dong, C, Yan, X.
登録日2022-06-10
公開日2022-08-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T64
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Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the closed state
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2021-12-13
公開日2022-07-20
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T65
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Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the open state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2021-12-13
公開日2022-07-20
最終更新日2022-08-03
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
7OW2
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BU of 7ow2 by Molmil
E3 RING ligase binding domain with peptide
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase RNF187 peptide, E3 ubiquitin-protein ligase TRIM7, ...
著者James, L.C.
登録日2021-06-16
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献E3 ligase targeting domain
To Be Published
8A8X
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TRIM7 PRYSPRY in complex with a MNV1-NS3 peptide HDDFGLQ
分子名称: E3 ubiquitin-protein ligase TRIM7, MNV1-NS3 C term peptide
著者Luptak, J.
登録日2022-06-24
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.
Viruses, 14, 2022
8A5L
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TRIM7 PRYSPRY in complex with a 2BC peptide TIEALFQ
分子名称: 2BC peptide TIEALFQ, D(-)-TARTARIC ACID, E3 ubiquitin-protein ligase TRIM7
著者Luptak, J.
登録日2022-06-15
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.622 Å)
主引用文献TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.
Viruses, 14, 2022
8A5M
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BU of 8a5m by Molmil
TRIM7 PRYSPRY in complex with a MNV1-NS6 peptide LEALEFQ
分子名称: E3 ubiquitin-protein ligase TRIM7, MNV1-NS6 peptide LEALEFQ, PHOSPHATE ION
著者Luptak, J.
登録日2022-06-15
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.918 Å)
主引用文献TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.
Viruses, 14, 2022
7OVX
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E3 RING ligase binding domain
分子名称: E3 ubiquitin-protein ligase TRIM7, Peptide G
著者James, L.C.
登録日2021-06-15
公開日2022-06-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献E3 ligase targeting domain
To Be Published
7WUG
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BU of 7wug by Molmil
GID subcomplex: Gid12 bound Substrate Receptor Scaffolding module
分子名称: Glucose-induced degradation protein 8, HLJ1_G0042170.mRNA.1.CDS.1, Vacuolar import and degradation protein 24, ...
著者Qiao, S, Cheng, J.D, Schulman, B.A.
登録日2022-02-08
公開日2022-06-08
最終更新日2022-06-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation.
Nat Commun, 13, 2022
7TZC
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A drug and ATP binding site in type 1 ryanodine receptor
分子名称: (2S)-3-(octadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)-yl)methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Melville, Z, Dridi, H, Yuan, Q, Reiken, S, Anetta, W, Liu, Y, Clarke, O.B, Marks, A.R.
登録日2022-02-15
公開日2022-05-18
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献A drug and ATP binding site in type 1 ryanodine receptor.
Structure, 30, 2022
7QS3
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Crystal structure of B30.2 PRYSPRY domain of TRIM16
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Tripartite motif-containing protein 16
著者Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC)
登録日2022-01-12
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal structure of B30.2 PRYSPRY domain of TRIM16
To Be Published
7QS1
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Crystal structure of B30.2 PRYSPRY domain of TRIM11
分子名称: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase TRIM11, SULFATE ION
著者Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC)
登録日2022-01-12
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure of B30.2 PRYSPRY domain of TRIM11
To Be Published
7QS2
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Crystal structure of B30.2 PRYSPRY domain of TRIM15
分子名称: 1,2-ETHANEDIOL, IODIDE ION, TRIM15
著者Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC)
登録日2022-01-12
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of B30.2 PRYSPRY domain of TRIM15
To Be Published
7QS5
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BU of 7qs5 by Molmil
Crystal structure of B30.2 PRYSPRY domain of TRIM67
分子名称: 1,2-ETHANEDIOL, Tripartite motif-containing protein 67
著者Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC)
登録日2022-01-12
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of B30.2 PRYSPRY domain of TRIM67
To Be Published
7QRY
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BU of 7qry by Molmil
Crystal structure of B30.2 PRYSPRY domain of MID1
分子名称: E3 ubiquitin-protein ligase Midline-1
著者Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC)
登録日2022-01-12
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Crystal structure of B30.2 PRYSPRY domain of MID1
To Be Published
7QRZ
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Crystal structure of B30.2 PRYSPRY domain of MID2
分子名称: 1,2-ETHANEDIOL, Probable E3 ubiquitin-protein ligase MID2, SULFATE ION
著者Chaikuad, A, Zhubi, R, Knapp, S, Structural Genomics Consortium (SGC)
登録日2022-01-12
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Crystal structure of B30.2 PRYSPRY domain of MID2
To Be Published
7QS0
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Crystal structure of B30.2 PRYSPRY domain of TRIM10
分子名称: 1,2-ETHANEDIOL, Tripartite motif-containing protein 10
著者Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC)
登録日2022-01-12
公開日2022-05-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of B30.2 PRYSPRY domain of TRIM10
To Be Published
7TDK
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BU of 7tdk by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 3 (Dataset-A)
分子名称: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDH
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BU of 7tdh by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in open conformation
分子名称: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDI
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BU of 7tdi by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 2 (Dataset-A)
分子名称: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDG
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BU of 7tdg by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in inactivated conformation (Dataset-A)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDJ
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BU of 7tdj by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 1(Dataset-A)
分子名称: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7MBM
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BU of 7mbm by Molmil
Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode01
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Park, S.H, Ayoub, A, Lee, Y.T, Dou, Y, Cho, U.
登録日2021-04-01
公開日2021-12-29
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY
主引用文献Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes.
Biochemistry, 61, 2022
7MBN
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BU of 7mbn by Molmil
Cryo-EM structure of MLL1-NCP (H3K4M) complex, mode02
分子名称: DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
著者Park, S.H, Ayoub, A, Lee, Y.T, Dou, Y, Cho, U.
登録日2021-04-01
公開日2021-12-29
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY
主引用文献Regulation of MLL1 Methyltransferase Activity in Two Distinct Nucleosome Binding Modes.
Biochemistry, 61, 2022
7M6A
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BU of 7m6a by Molmil
High resolution structure of the membrane embedded skeletal muscle ryanodine receptor
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Melville, Z, Kim, K, Clarke, O.B, Marks, A.R.
登録日2021-03-25
公開日2021-09-08
最終更新日2022-01-19
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor.
Structure, 30, 2022

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件を2024-06-12に公開中

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