5FMF
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![BU of 5fmf by Molmil](/molmil-images/mine/5fmf) | the P-lobe of RNA polymerase II pre-initiation complex | 分子名称: | DNA REPAIR HELICASE RAD25, SSL2, DNA REPAIR HELICASE RAD3, ... | 著者 | Murakami, K, Tsai, K, Kalisman, N, Bushnell, D.A, Asturias, F.J, Kornberg, R.D. | 登録日 | 2015-11-03 | 公開日 | 2015-11-25 | 最終更新日 | 2017-07-12 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Structure of an RNA Polymerase II Pre-Initiation Complex Proc.Natl.Acad.Sci.USA, 112, 2015
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8GXS
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![BU of 8gxs by Molmil](/molmil-images/mine/8gxs) | PIC-Mediator in complex with +1 nucleosome (T40N) in H-binding state | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X. | 登録日 | 2022-09-21 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | 主引用文献 | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
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8GXQ
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![BU of 8gxq by Molmil](/molmil-images/mine/8gxq) | PIC-Mediator in complex with +1 nucleosome (T40N) in MH-binding state | 分子名称: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | 著者 | Chen, X, Wang, X, Liu, W, Ren, Y, Qu, X, Li, J, Yin, X, Xu, Y. | 登録日 | 2022-09-21 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (5.04 Å) | 主引用文献 | Structures of +1 nucleosome-bound PIC-Mediator complex. Science, 378, 2022
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5OIK
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![BU of 5oik by Molmil](/molmil-images/mine/5oik) | Structure of an RNA polymerase II-DSIF transcription elongation complex | 分子名称: | DNA (43-MER), DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, ... | 著者 | Bernecky, C, Plitzko, J.M, Cramer, P. | 登録日 | 2017-07-18 | 公開日 | 2017-09-13 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structure of a transcribing RNA polymerase II-DSIF complex reveals a multidentate DNA-RNA clamp. Nat. Struct. Mol. Biol., 24, 2017
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8H0V
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![BU of 8h0v by Molmil](/molmil-images/mine/8h0v) | RNA polymerase II transcribing a chromatosome (type I) | 分子名称: | DNA (261-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Hirano, R, Ehara, H, Tomoya, K, Takizawa, Y, Sekine, S, Kurumizaka, H. | 登録日 | 2022-09-30 | 公開日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1. Nat Commun, 13, 2022
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8H0W
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![BU of 8h0w by Molmil](/molmil-images/mine/8h0w) | RNA polymerase II transcribing a chromatosome (type II) | 分子名称: | DNA (261-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Hirano, R, Ehara, H, Tomoya, K, Takizawa, Y, Sekine, S, Kurumizaka, H. | 登録日 | 2022-09-30 | 公開日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural basis of RNA polymerase II transcription on the chromatosome containing linker histone H1. Nat Commun, 13, 2022
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2WB1
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![BU of 2wb1 by Molmil](/molmil-images/mine/2wb1) | The complete structure of the archaeal 13-subunit DNA-directed RNA Polymerase | 分子名称: | DNA-DIRECTED RNA POLYMERASE RPO10 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO11 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO12 SUBUNIT, ... | 著者 | Korkhin, Y, Unligil, U.M, Littlefield, O, Nelson, P.J, Stuart, D.I, Sigler, P.B, Bell, S.D, Abrescia, N.G.A. | 登録日 | 2009-02-19 | 公開日 | 2009-05-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | 主引用文献 | Evolution of Complex RNA Polymerase: The Complete Archaeal RNA Polymerase Structure Plos Biol., 7, 2009
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3AEV
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![BU of 3aev by Molmil](/molmil-images/mine/3aev) | Crystal structure of a/eIF2alpha-aDim2p-rRNA complex from Pyrococcus horikoshii OT3 | 分子名称: | Putative uncharacterized protein PH1566, RNA (5'-R(*GP*GP*AP*UP*CP*AP*CP*CP*UP*CP*C)-3'), Translation initiation factor 2 subunit alpha | 著者 | Tanokura, M, Jia, M.Z, Nagata, K. | 登録日 | 2010-02-10 | 公開日 | 2010-04-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | An archaeal Dim2-like protein, aDim2p, forms a ternary complex with a/eIF2 alpha and the 3' end fragment of 16S rRNA J.Mol.Biol., 398, 2010
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5OT2
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![BU of 5ot2 by Molmil](/molmil-images/mine/5ot2) | RNA polymerase II elongation complex in the presence of 3d-Napht-A | 分子名称: | 2-ethyl-7-methoxy-naphthalene, DNA non-template strand, DNA template strand, ... | 著者 | Malvezzi, S, Farnung, L, Aloisi, C, Angelov, T, Cramer, P, Sturla, S.J. | 登録日 | 2017-08-19 | 公開日 | 2017-11-01 | 最終更新日 | 2019-07-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Mechanism of RNA polymerase II stalling by DNA alkylation. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5OQM
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![BU of 5oqm by Molmil](/molmil-images/mine/5oqm) | STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH AND CORE MEDIATOR | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Urlaub, H, Cramer, P. | 登録日 | 2017-08-13 | 公開日 | 2018-05-09 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature, 551, 2017
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5OQJ
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![BU of 5oqj by Molmil](/molmil-images/mine/5oqj) | STRUCTURE OF YEAST TRANSCRIPTION PRE-INITIATION COMPLEX WITH TFIIH | 分子名称: | DNA repair helicase RAD25, DNA repair helicase RAD3, DNA-directed RNA polymerase II subunit RPB1, ... | 著者 | Schilbach, S, Hantsche, M, Tegunov, D, Dienemann, C, Wigge, C, Henning, U, Cramer, P. | 登録日 | 2017-08-11 | 公開日 | 2018-04-25 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structures of transcription pre-initiation complex with TFIIH and Mediator. Nature, 551, 2017
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8HE5
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![BU of 8he5 by Molmil](/molmil-images/mine/8he5) | RNA polymerase II elongation complex bound with Rad26 and Elf1, stalled at SHL(-3.5) of the nucleosome | 分子名称: | DNA (198-MER), DNA repair protein, DNA-directed RNA polymerase subunit, ... | 著者 | Osumi, K, Kujirai, T, Ehara, H, Kinoshita, C, Saotome, M, Kagawa, W, Sekine, S, Takizawa, Y, Kurumizaka, H. | 登録日 | 2022-11-07 | 公開日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (6.95 Å) | 主引用文献 | Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome. J.Mol.Biol., 435, 2023
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2WAQ
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![BU of 2waq by Molmil](/molmil-images/mine/2waq) | The complete structure of the archaeal 13-subunit DNA-directed RNA Polymerase | 分子名称: | DNA-DIRECTED RNA POLYMERASE RPO10 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO11 SUBUNIT, DNA-DIRECTED RNA POLYMERASE RPO12 SUBUNIT, ... | 著者 | Korkhin, Y, Unligil, U.M, Littlefield, O, Nelson, P.J, Stuart, D.I, Sigler, P.B, Bell, S.D, Abrescia, N.G.A. | 登録日 | 2009-02-11 | 公開日 | 2009-05-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure. Plos Biol., 7, 2009
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3CDI
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![BU of 3cdi by Molmil](/molmil-images/mine/3cdi) | Crystal structure of E. coli PNPase | 分子名称: | Polynucleotide phosphorylase | 著者 | Shi, Z, Yang, W.Z, Lin-Chao, S, Chak, K.F, Yuan, H.S. | 登録日 | 2008-02-27 | 公開日 | 2008-12-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of Escherichia coli PNPase: central channel residues are involved in processive RNA degradation. Rna, 14, 2008
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2VUM
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![BU of 2vum by Molmil](/molmil-images/mine/2vum) | Alpha-amanitin inhibited complete RNA polymerase II elongation complex | 分子名称: | 5'-D(*AP*AP*AP*CP*TP*AP*CP*TP*TP*GP *AP*GP*CP*T)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP *GP*TP*TP*AP*CP*GP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... | 著者 | Brueckner, F, Cramer, P. | 登録日 | 2008-05-27 | 公開日 | 2008-06-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural Basis of Transcription Inhibition by Alpha-Amanitin and Implications for RNA Polymerase II Translocation. Nat.Struct.Mol.Biol., 15, 2008
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5K0Y
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![BU of 5k0y by Molmil](/molmil-images/mine/5k0y) | m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... | 著者 | Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. | 登録日 | 2016-05-17 | 公開日 | 2016-07-13 | 最終更新日 | 2018-04-18 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
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5LM7
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![BU of 5lm7 by Molmil](/molmil-images/mine/5lm7) | Crystal structure of the lambda N-Nus factor complex | 分子名称: | 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ... | 著者 | Said, N, Santos, K, Weber, G, Wahl, M.C. | 登録日 | 2016-07-29 | 公開日 | 2017-04-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Structural basis for lambda N-dependent processive transcription antitermination. Nat Microbiol, 2, 2017
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5MS0
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![BU of 5ms0 by Molmil](/molmil-images/mine/5ms0) | |
5MQF
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![BU of 5mqf by Molmil](/molmil-images/mine/5mqf) | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ... | 著者 | Bertram, K, Hartmuth, K, Kastner, B. | 登録日 | 2016-12-20 | 公開日 | 2017-03-22 | 最終更新日 | 2018-11-21 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature, 542, 2017
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2Y0S
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![BU of 2y0s by Molmil](/molmil-images/mine/2y0s) | Crystal structure of Sulfolobus shibatae RNA polymerase in P21 space group | 分子名称: | DNA-DIRECTED RNA POLYMERASE, DNA-DIRECTED RNA POLYMERASE SUBUNIT A'', DNA-DIRECTED RNA POLYMERASE SUBUNIT D, ... | 著者 | Wojtas, M, Peralta, B, Ondiviela, M, Mogni, M, Bell, S.D, Abrescia, N.G.A. | 登録日 | 2010-12-07 | 公開日 | 2011-02-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Archaeal RNA polymerase: the influence of the protruding stalk in crystal packing and preliminary biophysical analysis of the Rpo13 subunit. Biochem. Soc. Trans., 39, 2011
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2R92
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![BU of 2r92 by Molmil](/molmil-images/mine/2r92) | Elongation complex of RNA polymerase II with artificial RdRP scaffold | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Lehmann, E, Brueckner, F, Cramer, P. | 登録日 | 2007-09-12 | 公開日 | 2007-11-27 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Molecular basis of RNA-dependent RNA polymerase II activity. Nature, 450, 2007
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2R7Z
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![BU of 2r7z by Molmil](/molmil-images/mine/2r7z) | Cisplatin lesion containing RNA polymerase II elongation complex | 分子名称: | 5'-D(*CP*AP*AP*GP*TP*AP*G)-3', 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3', 5'-R(*UP*UP*UP*GP*AP*GP*GP*AP*GP*G)-3', ... | 著者 | Damsma, G.E, Alt, A, Brueckner, F, Carell, T, Cramer, P. | 登録日 | 2007-09-10 | 公開日 | 2007-11-20 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Mechanism of transcriptional stalling at cisplatin-damaged DNA. Nat.Struct.Mol.Biol., 14, 2007
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5MQ0
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![BU of 5mq0 by Molmil](/molmil-images/mine/5mq0) | Structure of a spliceosome remodeled for exon ligation | 分子名称: | 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ... | 著者 | Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. | 登録日 | 2016-12-19 | 公開日 | 2017-01-18 | 最終更新日 | 2020-10-07 | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | 主引用文献 | Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
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3CW2
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![BU of 3cw2 by Molmil](/molmil-images/mine/3cw2) | Crystal structure of the intact archaeal translation initiation factor 2 from Sulfolobus solfataricus . | 分子名称: | Translation initiation factor 2 subunit alpha, Translation initiation factor 2 subunit beta, Translation initiation factor 2 subunit gamma | 著者 | Stolboushkina, E.A, Nikonov, S.V, Nikulin, A.D, Blaesi, U, Manstein, D.J, Fedorov, R.V, Garber, M.B, Nikonov, O.S. | 登録日 | 2008-04-21 | 公開日 | 2009-01-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the intact archaeal translation initiation factor 2 demonstrates very high conformational flexibility in the alpha- and beta-subunits. J.Mol.Biol., 382, 2008
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2PMZ
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![BU of 2pmz by Molmil](/molmil-images/mine/2pmz) | Archaeal RNA polymerase from Sulfolobus solfataricus | 分子名称: | DNA-directed RNA polymerase subunit A, DNA-directed RNA polymerase subunit A", DNA-directed RNA polymerase subunit B, ... | 著者 | Murakami, K.S. | 登録日 | 2007-04-23 | 公開日 | 2008-02-12 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | The X-ray crystal structure of RNA polymerase from Archaea Nature, 451, 2008
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