5OT2

RNA polymerase II elongation complex in the presence of 3d-Napht-A

Summary for 5OT2

• Entry DOI: 10.2210/pdb5ot2/pdb
• Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase II subunit RPB11, ... (18 entities in total)
• Functional Keywords: inhibitor, complex, polymerase, transcription
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 15
• Total formula weight: 530696.01

Authors

Malvezzi, S.,Farnung, L.,Aloisi, C.,Angelov, T.,Cramer, P.,Sturla, S.J. (deposition date: 2017-08-19, release date: 2017-11-01, Last modification date: 2019-07-10)

• Primary citation: Malvezzi, S.,Farnung, L.,Aloisi, C.M.N.,Angelov, T.,Cramer, P.,Sturla, S.J.; Mechanism of RNA polymerase II stalling by DNA alkylation.; Proc. Natl. Acad. Sci. U.S.A., 114:12172-12177, 2017; PubMed: 29087308; DOI: 10.1073/pnas.1706592114

Experimental method

X-RAY DIFFRACTION (3.2 Å)