PDB: 124 件ウェブページステータス検索Chemie searchBIRD

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7LLA	Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate (EM map was generated in Cryosparc with non-uniform refinement) 分子名称: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION 著者 Wei, X, Marmorstein, R. 登録日 2021-02-03 公開日 2021-03-03 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nat.Struct.Mol.Biol., 28, 2021
7LIW	Local refinement of human ATP citrate lyase E599Q mutant ASH domain 分子名称: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... 著者 Wei, X, Marmorstein, R. 登録日 2021-01-28 公開日 2021-05-19 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nat.Struct.Mol.Biol., 28, 2021
6ZNW	Methanosaeta concilii ATP citrate lyase (D541A mutant) in complex with (3S)-citryl-CoA. 分子名称: (3S)-citryl-Coenzyme A, CITRATE ANION, Citrate lyase, ... 著者 Verschueren, K.H.G, Verstraete, K. 登録日 2020-07-06 公開日 2021-07-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.121 Å) 主引用文献 Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nat.Struct.Mol.Biol., 28, 2021
7RIG	Structure of ACLY-D1026A-substrates 分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... 著者 Wei, X, Marmorstein, R. 登録日 2021-07-19 公開日 2023-05-10 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
7RKZ	Structure of ACLY D1026A-substrates-asym-int 分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... 著者 Wei, X, Marmorstein, R. 登録日 2021-07-22 公開日 2023-05-10 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
7RMP	Structure of ACLY D1026A - substrates-asym 分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... 著者 Wei, X, Marmorstein, R. 登録日 2021-07-28 公開日 2023-05-10 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
7LJ9	Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate 分子名称: ACETYL COENZYME *A, ATP-citrate synthase, OXALOACETATE ION 著者 Wei, X, Marmorstein, R. 登録日 2021-01-28 公開日 2021-03-31 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase. Nat.Struct.Mol.Biol., 28, 2021
6O0H	Cryo-EM structure of human ATP-citrate lyase in complex with inhibitor NDI-091143 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, methyl 3-chloro-5-[(4,6-difluoro[1,1'-biphenyl]-3-yl)sulfamoyl]-4-hydroxybenzoate 著者 Wei, J, Tong, L. 登録日 2019-02-16 公開日 2019-04-17 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.67 Å) 主引用文献 An allosteric mechanism for potent inhibition of human ATP-citrate lyase. Nature, 568, 2019
6POE	Structure of ACLY in complex with CoA 分子名称: ATP-citrate synthase, COENZYME A 著者 Wei, X, Marmorstein, R. 登録日 2019-07-03 公開日 2019-12-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
6POF	Structure of human ATP citrate lyase 分子名称: ATP-citrate synthase 著者 Wei, X, Marmorstein, R. 登録日 2019-07-03 公開日 2020-01-01 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
6UIA	Structure of ATP citrate lyase with CoA in a partially open conformation 分子名称: ATP-citrate synthase, COENZYME A 著者 Wei, X, Marmorstein, R. 登録日 2019-09-30 公開日 2019-12-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
6UUZ	Structure of ACLY in the presence of citrate and CoA 分子名称: ATP-citrate synthase, COENZYME A 著者 Xuepeng, W, Ronen, M. 登録日 2019-11-01 公開日 2020-01-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
6UV5	Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate 分子名称: ACETYL COENZYME *A, ATP citrate lyase, OXALOACETATE ION 著者 Wei, X, Marmorstein, R. 登録日 2019-11-01 公開日 2019-12-25 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
6UUW	Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and CoA 分子名称: (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... 著者 Wei, X, Marmorstein, R. 登録日 2019-11-01 公開日 2019-12-25 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.85 Å) 主引用文献 Molecular basis for acetyl-CoA production by ATP-citrate lyase Nat.Struct.Mol.Biol., 27, 2020
6UI9	Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate 分子名称: ACETYL COENZYME *A, ACLY, OXALOACETATE ION 著者 Wei, X, Marmorstein, R. 登録日 2019-09-30 公開日 2019-12-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Molecular basis for acetyl-CoA production by ATP-citrate lyase Nat.Struct.Mol.Biol., 27, 2020
6HXJ	Structure of ATP citrate lyase from Chlorobium limicola in complex with citrate and coenzyme A. 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ATP-citrate lyase alpha-subunit, ATP-citrate lyase beta-subunit, ... 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
6HXI	Structure of ATP citrate lyase from Methanothrix soehngenii in complex with citrate and coenzyme A 分子名称: ACETATE ION, CITRATE ANION, COENZYME A, ... 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
6HXH	Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase,Human ATP citrate lyase, CITRATE ANION, ... 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
8G5C	Structure of ACLY-D1026A-substrates, local refinement of ASH domain 分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... 著者 Xuepeng, W, Ronen, M. 登録日 2023-02-12 公開日 2023-05-10 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
8G1F	Structure of ACLY-D1026A-products 分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Wei, X, Marmorstein, R. 登録日 2023-02-02 公開日 2023-05-10 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
8G5D	Structure of ACLY-D1026A-products, local refinement of ASH domain 分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Wei, X, Marmorstein, R. 登録日 2023-02-13 公開日 2023-05-10 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
8G1E	Structure of ACLY-D1026A-products-asym 分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Wei, X, Marmorstein, R. 登録日 2023-02-02 公開日 2023-05-10 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
8GRF	Crystal structure of F-box protein in the ternary complex with adaptor protein Skp1(DL) and its substrate 分子名称: 1,2-ETHANEDIOL, Citrate synthase, E3 ubiquitin ligase complex SCF subunit, ... 著者 Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. 登録日 2022-09-01 公開日 2023-04-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023
8GRE	F-box protein in complex with skp1(FL) and substrate 分子名称: Citrate synthase, E3 ubiquitin ligase complex SCF subunit, F-box protein UCC1, ... 著者 Nishio, K, Nakatsukasa, K, Kamura, T, Mizushima, T. 登録日 2022-09-01 公開日 2023-04-26 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci Adv, 9, 2023

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