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1SFQ
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BU of 1sfq by Molmil
Fast form of thrombin mutant R(77a)A bound to PPACK
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, SODIUM ION, ...
著者Pineda, A.O, Carrell, C.J, Bush, L.A, Prasad, S, Caccia, S, Chen, Z.W, Mathews, F.S, Di Cera, E.
登録日2004-02-20
公開日2004-06-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Molecular dissection of na+ binding to thrombin.
J.Biol.Chem., 279, 2004
3EAD
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BU of 3ead by Molmil
Crystal structure of CALX-CBD1
分子名称: CALCIUM ION, GLYCEROL, Na/Ca exchange protein
著者Zheng, L, Wang, M.
登録日2008-08-25
公開日2009-09-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions.
J.Biol.Chem., 285, 2010
5WU7
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BU of 5wu7 by Molmil
Crystal structure of GH57-type branching enzyme from hyperthermophilic archaeon Pyrococcus horikoshii
分子名称: GLYCEROL, Uncharacterized protein
著者Na, S, Jo, I, Ha, N.-C.
登録日2016-12-16
公開日2017-03-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural basis for the transglycosylase activity of a GH57-type glycogen branching enzyme from Pyrococcus horikoshii.
Biochem. Biophys. Res. Commun., 484, 2017
1SG8
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BU of 1sg8 by Molmil
Crystal structure of the procoagulant fast form of thrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, thrombin
著者Pineda, A.O, Carrell, C.J, Bush, L.A, Prasad, S, Caccia, S, Chen, Z.W, Mathews, F.S, Di Cera, E.
登録日2004-02-23
公開日2004-06-08
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular dissection of na+ binding to thrombin.
J.Biol.Chem., 279, 2004
3FI1
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BU of 3fi1 by Molmil
NhaA dimer model
分子名称: Na(+)/H(+) antiporter nhaA
著者Appel, M, Hizlan, D, Vinothkumar, K.R, Ziegler, C, Kuehlbrandt, W.
登録日2008-12-10
公開日2009-01-13
最終更新日2024-02-21
実験手法ELECTRON CRYSTALLOGRAPHY (7 Å)
主引用文献Conformations of NhaA, the Na/H exchanger from Escherichia coli, in the pH-activated and ion-translocating states
J.Mol.Biol., 386, 2009
6KNT
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BU of 6knt by Molmil
Crystal structure of the metallo-beta-lactamase fold protein YhfI from Bacillus subtilis (space group P4332)
分子名称: Putative metal-dependent hydrolase, ZINC ION
著者Na, H.W, Namgung, B, Song, W.S, Yoon, S.I.
登録日2019-08-07
公開日2019-09-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and biochemical analyses of the metallo-beta-lactamase fold protein YhfI from Bacillus subtilis.
Biochem.Biophys.Res.Commun., 519, 2019
2E30
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BU of 2e30 by Molmil
Solution structure of the cytoplasmic region of Na+/H+ exchanger 1 complexed with essential cofactor calcineurin B homologous protein 1
分子名称: CALCIUM ION, Calcium-binding protein p22, Sodium/hydrogen exchanger 1
著者Mishima, M, Wakabayashi, S, Kojima, C.
登録日2006-11-19
公開日2006-12-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the cytoplasmic region of Na+/H+ exchanger 1 complexed with essential cofactor calcineurin B homologous protein 1
J.Biol.Chem., 282, 2007
4US4
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BU of 4us4 by Molmil
Crystal Structure of the Bacterial NSS Member MhsT in an Occluded Inward-Facing State (lipidic cubic phase form)
分子名称: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, SODIUM ION, ...
著者Malinauskaite, L, Quick, M, Reinhard, L, Lyons, J.A, Yano, H, Javitch, J.A, Nissen, P.
登録日2014-07-02
公開日2014-09-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Mechanism for Intracellular Release of Na+ by Neurotransmitter/Sodium Symporters
Nat.Struct.Mol.Biol., 21, 2014
7RPK
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BU of 7rpk by Molmil
Cryo-EM structure of murine Dispatched in complex with Sonic hedgehog
分子名称: (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A.
登録日2021-08-03
公開日2021-10-27
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
7QTV
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BU of 7qtv by Molmil
Beryllium fluoride form of the Na+,K+-ATPase (E2-BeFx)
分子名称: 1-O-decanoyl-beta-D-tagatofuranosyl beta-D-allopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Fruergaard, M.U, Dach, I, Andersen, J.L, Ozol, M, Shahsavar, A, Quistgaard, E.M, Poulsen, H, Fedosova, N.U, Nissen, P.
登録日2022-01-16
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.05 Å)
主引用文献The Na + ,K + -ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state.
J.Biol.Chem., 298, 2022
7RPH
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BU of 7rph by Molmil
Cryo-EM structure of murine Dispatched 'R' conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Lauryl Maltose Neopentyl Glycol, ...
著者Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A.
登録日2021-08-03
公開日2021-10-27
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
7RPI
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BU of 7rpi by Molmil
Cryo-EM structure of murine Dispatched 'T' conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Lauryl Maltose Neopentyl Glycol, ...
著者Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A.
登録日2021-08-03
公開日2021-10-27
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Dispatched uses Na + flux to power release of lipid-modified Hedgehog.
Nature, 599, 2021
4NUI
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BU of 4nui by Molmil
Crystal structure of cobalt-bound Na-ASP-2
分子名称: Ancylostoma secreted protein 2, COBALT (II) ION
著者Hofmann, A.
登録日2013-12-03
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Probing the equatorial groove of the hookworm protein and vaccine candidate antigen, Na-ASP-2.
Int.J.Biochem.Cell Biol., 50, 2014
2FWU
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BU of 2fwu by Molmil
Second Ca2+ binding domain of the Na,Ca-exchanger (NCX1)
分子名称: CALCIUM ION, Sodium/calcium exchanger 1
著者Hilge, M, Vuister, G.W, Aelen, J.
登録日2006-02-03
公開日2006-04-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Ca(2+) regulation in the na(+)/ca(2+) exchanger involves two markedly different ca(2+) sensors
Mol.Cell, 22, 2006
4UET
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BU of 4uet by Molmil
Diversity in the structures and ligand binding sites among the fatty acid and retinol binding proteins of nematodes revealed by Na-FAR-1 from Necator americanus
分子名称: NEMATODE FATTY ACID RETINOID BINDING PROTEIN
著者Rey-Burusco, M.F, Ibanez Shimabukuro, M, Griffiths, K, Cooper, A, Kennedy, M.W, Corsico, B, Smith, B.O, Griffiths, K.
登録日2014-12-18
公開日2015-09-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Diversity in the Structures and Ligand Binding Sites of Nematode Fatty Acid and Retinol Binding Proteins Revealed by Na-Far-1 from Necator Americanus.
Biochem.J., 471, 2015
4U9O
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BU of 4u9o by Molmil
Crystal structure of NqrA from Vibrio cholerae
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Na(+)-translocating NADH-quinone reductase subunit A
著者Fritz, G.
登録日2014-08-06
公開日2014-12-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase.
Nature, 516, 2014
4U9S
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BU of 4u9s by Molmil
Crystal structure of NqrC from Vibrio cholerae
分子名称: BROMIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Fritz, G.
登録日2014-08-06
公開日2014-12-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase.
Nature, 516, 2014
4UAJ
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BU of 4uaj by Molmil
Crystal structure of NqrF in hexagonal space group
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Na(+)-translocating NADH-quinone reductase subunit F, SULFATE ION
著者Fritz, G.
登録日2014-08-10
公開日2015-08-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7019 Å)
主引用文献Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase.
Nature, 516, 2014
4US3
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BU of 4us3 by Molmil
Crystal Structure of the bacterial NSS member MhsT in an Occluded Inward-Facing State
分子名称: DODECYL-ALPHA-D-MALTOSIDE, SODIUM ION, TRANSPORTER, ...
著者Malinauskaite, L, Quick, M, Reinhard, L, Lyons, J.A, Yano, H, Javitch, J.A, Nissen, P.
登録日2014-07-02
公開日2014-09-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.098 Å)
主引用文献A Mechanism for Intracellular Release of Na+ by Neurotransmitter/Sodium Symporters
Nat.Struct.Mol.Biol., 21, 2014
8A1X
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BU of 8a1x by Molmil
Sodium pumping NADH-quinone oxidoreductase with inhibitor DQA
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, DODECYL-BETA-D-MALTOSIDE, FE2/S2 (INORGANIC) CLUSTER, ...
著者Hau, J.-L, Kaltwasser, S, Vonck, J, Fritz, G, Steuber, J.
登録日2022-06-02
公開日2023-06-14
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Conformational coupling of redox-driven Na + -translocation in Vibrio cholerae NADH:quinone oxidoreductase.
Nat.Struct.Mol.Biol., 30, 2023
8A1Y
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BU of 8a1y by Molmil
Sodium pumping NADH-quinone oxidoreductase with inhibitor HQNO
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, DODECYL-BETA-D-MALTOSIDE, ...
著者Hau, J.-L, Kaltwasser, S, Vonck, J, Fritz, G, Steuber, J.
登録日2022-06-02
公開日2023-06-14
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Conformational coupling of redox-driven Na + -translocation in Vibrio cholerae NADH:quinone oxidoreductase.
Nat.Struct.Mol.Biol., 30, 2023
7Z04
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BU of 7z04 by Molmil
10 mM Rb+ soak of beryllium fluoride inhibited Na+,K+-ATPase, E2-BeFx (rigid body model)
分子名称: BERYLLIUM TRIFLUORIDE ION, FXYD domain-containing ion transport regulator, MAGNESIUM ION, ...
著者Fruergaard, M.U, Dach, I, Andersen, J.L, Ozol, M, Shasavar, A, Quistgaard, E.M, Poulsen, H, Fedosova, N.U, Nissen, P.
登録日2022-02-22
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (7.5 Å)
主引用文献The Na + ,K + -ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state.
J.Biol.Chem., 298, 2022
7YZR
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BU of 7yzr by Molmil
50 mM Rb+ soak of beryllium fluoride inhibited Na+,K+-ATPase, E2-BeFx (rigid body model)
分子名称: BERYLLIUM TRIFLUORIDE ION, FXYD domain-containing ion transport regulator, MAGNESIUM ION, ...
著者Fruergaard, M.U, Dach, I, Andersen, J.L, Ozol, M, Shasavar, A, Quistgaard, E.M, Poulsen, H, Fedosova, N.U, Nissen, P.
登録日2022-02-21
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (6.92 Å)
主引用文献The Na + ,K + -ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state.
J.Biol.Chem., 298, 2022
8I5Y
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BU of 8i5y by Molmil
Structure of human Nav1.7 in complex with vixotrigine
分子名称: (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
著者Wu, Q.R, Yan, N.
登録日2023-01-26
公開日2023-06-14
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural mapping of Na v 1.7 antagonists.
Nat Commun, 14, 2023
7R63
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BU of 7r63 by Molmil
Nb82, a nanobody against voltage gated sodium channels Nav1.4 and Nav1.5
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, CHLORIDE ION, Nanobody Nb82, ...
著者Srinivasan, L, Gabelli, S.B.
登録日2021-06-22
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Development of high-affinity nanobodies specific for Na V 1.4 and Na V 1.5 voltage-gated sodium channel isoforms.
J.Biol.Chem., 298, 2022

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