7X23

Cryo-EM structure of non gastric H,K-ATPase alpha2 SPWC mutant in 3Na+E1-AMPPCPF state

Summary for 7X23

• Entry DOI: 10.2210/pdb7x23/pdb
• EMDB information: 32956
• Descriptor: Potassium-transporting ATPase alpha chain 2, Sodium/potassium-transporting ATPase subunit beta-1, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (6 entities in total)
• Functional Keywords: p-type atpase, transporter, proton pump, kidney, colon, airway, membrane protein
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 2
• Total formula weight: 147457.91

Authors

Abe, K.,Nakanishi, H.,Young, V.,Artigas, P. (deposition date: 2022-02-25, release date: 2022-10-05)

• Primary citation: Young, V.C.,Nakanishi, H.,Meyer, D.J.,Nishizawa, T.,Oshima, A.,Artigas, P.,Abe, K.; Structure and function of H + /K + pump mutants reveal Na + /K + pump mechanisms.; Nat Commun, 13:5270-5270, 2022; PubMed: 36085139; DOI: 10.1038/s41467-022-32793-0

Experimental method

ELECTRON MICROSCOPY (3.2 Å)