8XU5
 
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6D9S
 | | The (p)ppGpp-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | | 分子名称: | DI(HYDROXYETHYL)ETHER, GUANOSINE-5',3'-TETRAPHOSPHATE, Hypoxanthine phosphoribosyltransferase, ... | | 著者 | Satyshur, K.A, Dubiel, K, Anderson, B, Wolak, C, Keck, J.L. | | 登録日 | 2018-04-30 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.105 Å) | | 主引用文献 | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction.
Elife, 8, 2019
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8XPG
 | | The Crystal Structure of polo box domain of Plk4 from Biortus. | | 分子名称: | SULFATE ION, Serine/threonine-protein kinase PLK4 | | 著者 | Wang, F, Cheng, W, Lv, Z, Meng, Q, Zhang, B. | | 登録日 | 2024-01-03 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The Crystal Structure of polo box domain of Plk4 from Biortus.
To Be Published
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5D9K
 | | Rsk2 N-terminal Kinase in Complex with BI-D1870 | | 分子名称: | (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5H)-one, GLYCEROL, Ribosomal protein S6 kinase alpha-3 | | 著者 | Appleton, B.A. | | 登録日 | 2015-08-18 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Discovery of Potent and Selective RSK Inhibitors as Biological Probes.
J.Med.Chem., 58, 2015
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9CK3
 | | Cryo-EM structure of in-vitro alpha-synuclein fibril | | 分子名称: | Alpha-synuclein | | 著者 | Sanchez, J.C, Borcik, C.G, Tonelli, M, Sibert, B, Rienstra, C.M, Wright, E.R. | | 登録日 | 2024-07-08 | | 公開日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.04 Å) | | 主引用文献 | Multimodal High-Resolution Structure Determination Of Alpha-Synuclein Fibrils
To Be Published
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8XGC
 | | Structure of yeast replisome associated with FACT and histone hexamer, Composite map | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... | | 著者 | Li, N, Gao, Y, Yu, D, Gao, N, Zhai, Y. | | 登録日 | 2023-12-15 | | 公開日 | 2024-02-14 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Parental histone transfer caught at the replication fork.
Nature, 627, 2024
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8VXU
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8VE1
 | | Human transthyretin covalently modified with A2-derived stilbene in the canonical conformation | | 分子名称: | 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoic acid, Transthyretin | | 著者 | Basanta, B, Nugroho, K, Yan, N, Kline, G.M, Tsai, F.J, Wu, M, Kelly, J.W, Lander, G.C. | | 登録日 | 2023-12-18 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | The conformational landscape of human transthyretin revealed by cryo-EM
To Be Published
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8VZZ
 | | Q108K:K40L:T51V:T53S:Y19W:R58W mutant of hCRBPII bound to synthetic fluorophore TD-1V | | 分子名称: | (2E)-3-{5-[4-(dimethylamino)phenyl]thiophen-2-yl}but-2-enal, ACETATE ION, Retinol-binding protein 2 | | 著者 | Nosssoni, Z, Bingham, C.R, Geiger, J.H, Borhan, B. | | 登録日 | 2024-02-13 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | | 主引用文献 | Regulation of Absorption and Emission in a Protein/Fluorophore Complex.
Acs Chem.Biol., 2024
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5HL4
 | | Acoustic injectors for drop-on-demand serial femtosecond crystallography | | 分子名称: | COBALT HEXAMMINE(III), FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Roessler, C.G, Agarwal, R, Allaire, M, Alonso-Mori, R, Andi, B, Bachega, J.F.R, Bommer, M, Brewster, A.S, Browne, M.C, Chatterjee, R, Cho, E, Cohen, A.E, Cowan, M, Datwani, S, Davidson, V.L, Defever, J, Eaton, B, Ellson, R, Feng, Y, Ghislain, L.P, Glownia, J.M, Han, G, Hattne, J, Hellmich, J, Heroux, A, Ibrahim, M, Kern, J, Kuczewski, A, Lemke, H.T, Liu, P, Majlof, L, McClintock, W.M, Myers, S, Nelsen, S, Olechno, J, Orville, A.M, Sauter, N.K, Soares, A.S, Soltis, M.S, Song, H, Stearns, R.G, Tran, R, Tsai, Y, Uervirojnangkoorn, M, Wilmot, C.M, Yachandra, V, Yano, J, Yukl, E.T, Zhu, D, Zouni, A. | | 登録日 | 2016-01-14 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography.
Structure, 24, 2016
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9C83
 | | X-ray crystal structure of AmpC beta-lactamase with inhibitor | | 分子名称: | AmpC Beta-lactamase, N-[(3M)-3-(5-chloro-1,2,3-thiadiazol-4-yl)phenyl]-5-methyl-3-oxo-2,3-dihydro-1,2-oxazole-4-sulfonamide | | 著者 | Liu, F, Shoichet, B.K. | | 登録日 | 2024-06-11 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Improved correlations with score, hit-rate, and affinity as docking library and testing scale increase
To Be Published
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6XGW
 | | ISCth4 transposase, pre-reaction complex, PRC | | 分子名称: | DNA (32-MER), Mutator family transposase | | 著者 | Kosek, D, Dyda, F. | | 登録日 | 2020-06-18 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
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9BEI
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8WU6
 | | Structure of a Nerylneryl Diphosphate Synthase from Solanum lycopersicum | | 分子名称: | Nerylneryl diphosphate synthase CPT2, chloroplastic | | 著者 | Li, F.R, Wang, Q.L, Pan, X.M, Dong, L.B. | | 登録日 | 2023-10-20 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Discovery, Structure, and Engineering of a cis-Geranylfarnesyl Diphosphate Synthase.
Angew.Chem.Int.Ed.Engl., 63, 2024
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8VE5
 | | (Biarylamine-FT2-WT)1(C10A)3-human transthyretin in the compressed conformation | | 分子名称: | 2-[(3,5-DICHLORO-4-TRIOXIDANYLPHENYL)AMINO]BENZOIC ACID, Transthyretin | | 著者 | Basanta, B, Nugroho, K, Yan, N, Kline, G.M, Tsai, F.J, Wu, M, Kelly, J.W, Lander, G.C. | | 登録日 | 2023-12-18 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | The conformational landscape of human transthyretin revealed by cryo-EM
To Be Published
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8W02
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8VE6
 | | (Biarylamine-FT2-WT)1(C10A)3-human transthyretin in the frayed conformation | | 分子名称: | 2-[(3,5-DICHLORO-4-TRIOXIDANYLPHENYL)AMINO]BENZOIC ACID, Transthyretin | | 著者 | Basanta, B, Nugroho, K, Yan, N, Kline, G.M, Tsai, F.J, Wu, M, Kelly, J.W, Lander, G.C. | | 登録日 | 2023-12-18 | | 公開日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | The conformational landscape of human transthyretin revealed by cryo-EM
To Be Published
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5DH8
 | | Two divalent metal ions and conformational changes play roles in the hammerhead ribozyme cleavage reaction- G12A mutant in Zn2+ | | 分子名称: | 5'-R(*GP*GP*GP*CP*GP*U)-D(P*C)-R(P*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', RNA (48-MER), ZINC ION | | 著者 | Mir, A, Chen, J, Neau, D, Golden, B.L. | | 登録日 | 2015-08-29 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.297 Å) | | 主引用文献 | Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction.
Biochemistry, 54, 2015
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5ZUX
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8B5X
 | | Crystal structure of the SUN1-KASH6 9:6 complex | | 分子名称: | CHLORIDE ION, Inositol 1,4,5-triphosphate receptor associated 2, POTASSIUM ION, ... | | 著者 | Erlandsen, B.S, Gurusaran, M, Davies, O.R. | | 登録日 | 2022-09-25 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion.
Commun Biol, 7, 2024
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6O9U
 | | KirBac3.1 at a resolution of 2 Angstroms | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3,3',3''-phosphoryltripropanoic acid, BARIUM ION, ... | | 著者 | Gulbis, J.M, Clarke, O.B. | | 登録日 | 2019-03-15 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A constricted opening in Kir channels does not impede potassium conduction.
Nat Commun, 11, 2020
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8WCH
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9EM6
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8VE0
 | | Human transthyretin covalently modified with A2-derived stilbene in the compressed conformation | | 分子名称: | 3-(dimethylamino)-5-[(E)-2-(4-hydroxy-3,5-dimethylphenyl)ethenyl]benzoic acid, Transthyretin | | 著者 | Basanta, B, Nugroho, K, Yan, N, Kline, G.M, Tsai, F.J, Wu, M, Kelly, J.W, Lander, G.C. | | 登録日 | 2023-12-18 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | The conformational landscape of human transthyretin revealed by cryo-EM
To Be Published
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6HBY
 | | HLA class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope | | 分子名称: | 1,2-ETHANEDIOL, ARRPPLAELAALNLSGSRL 5T4 tumour epitope, HLA class II histocompatibility antigen, ... | | 著者 | MacLachlan, B, Rizkallah, P.J, Sewell, A.K, Cole, D.K, Godkin, A.J. | | 登録日 | 2018-08-13 | | 公開日 | 2019-08-14 | | 最終更新日 | 2020-01-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope.
J.Biol.Chem., 294, 2019
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