6NOG
 
 | | Poised-state Dot1L bound to the H2B-Ubiquitinated nucleosome | | 分子名称: | 601 DNA Strand 1, 601 DNA Strand 2, Histone H2A type 1, ... | | 著者 | Worden, E.J, Hoffmann, N.A, Wolberger, C. | | 登録日 | 2019-01-16 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
Cell, 176, 2019
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6NP9
 | | PD-L1 IgV domain V76T with fragment | | 分子名称: | Programmed cell death 1 ligand 1, SULFATE ION | | 著者 | Zhao, B, Perry, E. | | 登録日 | 2019-01-17 | | 公開日 | 2019-02-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | | 主引用文献 | Fragment-based screening of programmed death ligand 1 (PD-L1).
Bioorg. Med. Chem. Lett., 29, 2019
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8DUL
 | | Cryo-EM Structure of Antibody SKT05 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab SKT05 heavy chain, ... | | 著者 | Cerutti, G, Verardi, R, Roederer, M, Shapiro, L. | | 登録日 | 2022-07-27 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
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6G8R
 | | SP140 PHD-Bromodomain complex with scFv | | 分子名称: | 1,2-ETHANEDIOL, Nuclear body protein SP140, ZINC ION, ... | | 著者 | Fairhead, M, Graslund, S, Strain-Damerell, C, Picaud, S.S, Pike, A.C.W, Pinkas, D.M, Wigren, E, Preger, C, Persson Lotsholm, H, Ossipova, E, Filippakopoulos, P, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Structural Genomics Consortium (SGC) | | 登録日 | 2018-04-09 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | SP140 PHD-Bromodomain complex with scFv
To Be Published
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7PCQ
 | | Human carboxyhemoglobin bound to Staphylococcus aureus hemophore IsdB - 1:1 complex | | 分子名称: | Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein B, ... | | 著者 | De Bei, O, Gianquinto, E, Chirgadze, D.Y, Hardwick, S.W, Spyrakis, F, Luisi, B.F, Campanini, B. | | 登録日 | 2021-08-03 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction.
Proc.Natl.Acad.Sci.USA, 119, 2022
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5CTR
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6SLZ
 | | Crystal structure of human ROR gamma LBD in complex with a (quinolinoxymethyl)benzamide inverse agonist | | 分子名称: | (2~{S})-1-[2,4-bis(chloranyl)-3-[[2-methyl-4-(trifluoromethyl)quinolin-8-yl]oxymethyl]phenyl]carbonyl-~{N}-methyl-pyrrolidine-2-carboxamide, Nuclear receptor ROR-gamma | | 著者 | Amaudrut, J, Argiriadi, M.A, Barth, M, Breinlinger, E.C, Calderwood, D.J, Cusack, K.P, Kort, M.E, Montalbetti, C, Potin, D, Poupardin, O, Spitzer, L. | | 登録日 | 2019-08-21 | | 公開日 | 2020-09-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of human ROR gamma LBD in complex with a (quinolinoxymethyl)benzamide inverse agonist
To Be Published
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1NAW
 | | ENOLPYRUVYL TRANSFERASE | | 分子名称: | CYCLOHEXYLAMMONIUM ION, UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYL-TRANSFERASE | | 著者 | Schoenbrunn, E, Sack, S, Eschenburg, S, Perrakis, A, Krekel, F, Amrhein, N, Mandelkow, E. | | 登録日 | 1996-07-23 | | 公開日 | 1997-07-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin.
Structure, 4, 1996
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8DUN
 | | Cryo-EM Structure of Antibody SKW11 in complex with Western Equine Encephalitis Virus spike (local refinement from VLP particles) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody SKW11 heavy chain, ... | | 著者 | Cerutti, G, Verardi, R, Roederer, M, Shapiro, L. | | 登録日 | 2022-07-27 | | 公開日 | 2023-07-05 | | 実験手法 | ELECTRON MICROSCOPY (5.84 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
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5K8R
 | | Structure of human clustered protocadherin gamma B3 EC1-4 | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Nicoludis, J.M, Vogt, B.E, Gaudet, R. | | 登録日 | 2016-05-30 | | 公開日 | 2016-08-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Antiparallel protocadherin homodimers use distinct affinity- and specificity-mediating regions in cadherin repeats 1-4.
Elife, 5, 2016
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7OKS
 | | X-ray structure of soluble EPCR in P212121 space group | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(5-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Erausquin, E, Dichiara, M.G, Lopez-Sagaseta, J. | | 登録日 | 2021-05-18 | | 公開日 | 2022-04-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Identification of a broad lipid repertoire associated to the endothelial cell protein C receptor (EPCR).
Sci Rep, 12, 2022
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5F7Q
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6NCU
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7OKT
 | | X-ray structure of soluble EPCR in C2221 space group | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, ... | | 著者 | Erausquin, E, Dichiara, M.G, Lopez-Sagaseta, J. | | 登録日 | 2021-05-18 | | 公開日 | 2022-04-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Identification of a broad lipid repertoire associated to the endothelial cell protein C receptor (EPCR).
Sci Rep, 12, 2022
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8DNG
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7JQL
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-001, mRNA, and deacylated P-site tRNA at 3.00A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M. | | 登録日 | 2020-08-11 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens.
J.Med.Chem., 63, 2020
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6PSQ
 | | Escherichia coli RNA polymerase closed complex (TRPc) with TraR and rpsT P2 promoter | | 分子名称: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | | 登録日 | 2019-07-13 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
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6BT9
 | | Chitinase ChiA74 from Bacillus thuringiensis | | 分子名称: | CALCIUM ION, Chitinase | | 著者 | Juarez-Hernandez, E, Brieba, L.G, Torres-Larios, A, Jimenez-Sandoval, P, Barboza-Corona, J. | | 登録日 | 2017-12-05 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | The crystal structure of the chitinase ChiA74 of Bacillus thuringiensis has a multidomain assembly.
Sci Rep, 9, 2019
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6FPO
 | | High resolution structure of native Hydrogenase (Hyd-1) | | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Carr, S.B, Armstrong, F.A, Evans, R.M. | | 登録日 | 2018-02-11 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Mechanistic Exploitation of a Self-Repairing, Blocked Proton Transfer Pathway in an O2-Tolerant [NiFe]-Hydrogenase.
J. Am. Chem. Soc., 140, 2018
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6GEN
 | | Chromatin remodeller-nucleosome complex at 4.5 A resolution. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | | 著者 | Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B. | | 登録日 | 2018-04-27 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure and dynamics of the yeast SWR1-nucleosome complex.
Science, 362, 2018
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8EEV
 | | Venezuelan equine encephalitis virus-like particle in complex with Fab SKT-20 | | 分子名称: | Coat protein, Fab SKT20 heavy chain, Fab SKT20 light chain | | 著者 | Tsybovsky, Y, Pletnev, S, Verardi, R, Roederer, M, Kwong, P.D. | | 登録日 | 2022-09-07 | | 公開日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
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7K8Y
 | | Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ... | | 著者 | Abernathy, M.E, Barnes, C.O, Bjorkman, P.J. | | 登録日 | 2020-09-27 | | 公開日 | 2020-10-21 | | 最終更新日 | 2021-01-13 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
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8ONK
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8DWO
 | | Cryo-EM Structure of Eastern Equine Encephalitis Virus in complex with SKE26 Fab | | 分子名称: | Envelope glycoprotein E1, Envelope glycoprotein E2, SKE26 Fab Heavy Chain, ... | | 著者 | Pletnev, S, Verardi, R, Roedeger, M, Kwong, P. | | 登録日 | 2022-08-01 | | 公開日 | 2023-07-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Vaccine elicitation and structural basis for antibody protection against alphaviruses.
Cell, 186, 2023
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6G4E
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