6B63
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![BU of 6b63 by Molmil](/molmil-images/mine/6b63) | IMPase (AF2372) with 25 mM Asp | 分子名称: | (2R)-2,3-dihydroxypropyl (2S)-2,3-dihydroxypropyl hydrogen phosphate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, ... | 著者 | Goldstein, R.I, Roberts, M. | 登録日 | 2017-10-01 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.696 Å) | 主引用文献 | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B64
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![BU of 6b64 by Molmil](/molmil-images/mine/6b64) | IMPase (AF2372) with 25 mM Asp | 分子名称: | ASPARTIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, MAGNESIUM ION, ... | 著者 | Goldstein, R.I, Roberts, M. | 登録日 | 2017-10-01 | 公開日 | 2018-10-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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4ZQY
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6BAE
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![BU of 6bae by Molmil](/molmil-images/mine/6bae) | Trastuzumab Fab v3 in complex with CQFDLSTRRLKC | 分子名称: | Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ... | 著者 | Bzymek, K.P, King, J.D, Williams, J.C. | 登録日 | 2017-10-12 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag. Bioconjug. Chem., 29, 2018
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6BC3
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![BU of 6bc3 by Molmil](/molmil-images/mine/6bc3) | Cryo X-ray structure of sisomicin bound AAC-VIa | 分子名称: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, AAC 3-VI protein, COENZYME A | 著者 | Cuneo, M.J, Kumar, P, Serpersu, E.H. | 登録日 | 2017-10-20 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.047 Å) | 主引用文献 | A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Sci Adv, 4, 2018
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6BCC
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![BU of 6bcc by Molmil](/molmil-images/mine/6bcc) | Joint X-ray/neutron structure of human carbonic anhydrase II in complex with ethoxzolamide | 分子名称: | 6-ethoxy-1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION | 著者 | Kovalevsky, A, McKenna, R, Aggarwal, M. | 登録日 | 2017-10-20 | 公開日 | 2018-02-28 | 最終更新日 | 2023-10-04 | 実験手法 | NEUTRON DIFFRACTION (1.8 Å), X-RAY DIFFRACTION | 主引用文献 | "To Be or Not to Be" Protonated: Atomic Details of Human Carbonic Anhydrase-Clinical Drug Complexes by Neutron Crystallography and Simulation. Structure, 26, 2018
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4XW5
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![BU of 4xw5 by Molmil](/molmil-images/mine/4xw5) | X-ray structure of PKAc with ATP, CP20, calcium ions | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... | 著者 | Gerlits, O, Tian, J, Das, A, Taylor, S, Langan, P, Heller, T.W, Kovalevsky, A. | 登録日 | 2015-01-28 | 公開日 | 2015-05-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Phosphoryl Transfer Reaction Snapshots in Crystals: INSIGHTS INTO THE MECHANISM OF PROTEIN KINASE A CATALYTIC SUBUNIT. J.Biol.Chem., 290, 2015
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4ZBJ
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![BU of 4zbj by Molmil](/molmil-images/mine/4zbj) | UBN1 peptide bound to H3.3/H4/Asf1 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Histone H3, ... | 著者 | Marmorstein, R, Ricketts, M.D, Tang, Y. | 登録日 | 2015-04-14 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.248 Å) | 主引用文献 | Ubinuclein-1 confers histone H3.3-specific-binding by the HIRA histone chaperone complex. Nat Commun, 6, 2015
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2C59
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![BU of 2c59 by Molmil](/molmil-images/mine/2c59) | gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha-d-mannose and gdp-beta-l-galactose bound in the active site. | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, GDP-MANNOSE-3', ... | 著者 | Major, L.L, Wolucka, B.A, Naismith, J.H. | 登録日 | 2005-10-26 | 公開日 | 2005-11-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and Function of Gdp-Mannose-3',5'-Epimerase: An Enzyme which Performs Three Chemical Reactions at the Same Active Site. J.Am.Chem.Soc., 127, 2005
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6BC5
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4XHX
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4XIK
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5D9O
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![BU of 5d9o by Molmil](/molmil-images/mine/5d9o) | Crystal structure of PbGH5A, a glycoside hydrolase family 5 enzyme from Prevotella bryantii B14, E280A mutant in complex with cellotetraose | 分子名称: | B-1,4-endoglucanase, CALCIUM ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Morar, M, Stogios, P.J, Xu, X, Cui, H, Di Leo, R, Yim, V, Savchenko, A. | 登録日 | 2015-08-18 | 公開日 | 2015-11-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure-Function Analysis of a Mixed-linkage beta-Glucanase/Xyloglucanase from the Key Ruminal Bacteroidetes Prevotella bryantii B14. J.Biol.Chem., 291, 2016
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6B66
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8APU
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![BU of 8apu by Molmil](/molmil-images/mine/8apu) | Crystal Structure of H. influenzae TrmD in complex with Compound 14 | 分子名称: | 6-[[4-(aminomethyl)phenyl]methylamino]pyridine-3-carboxamide, CITRIC ACID, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Hall, G, Cowan, R, Carr, M.D. | 登録日 | 2022-08-10 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors. Bioorg.Med.Chem.Lett., 90, 2023
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4ZBZ
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6B4Z
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![BU of 6b4z by Molmil](/molmil-images/mine/6b4z) | Schistosoma mansoni (Blood Fluke) Sulfotransferase, T157S Mutant | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein | 著者 | Taylor, A.B. | 登録日 | 2017-09-27 | 公開日 | 2018-10-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum? Int.J.Parasitol., 2020
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5DBB
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8APT
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![BU of 8apt by Molmil](/molmil-images/mine/8apt) | Crystal Structure of H. influenzae TrmD in complex with Compound 13 | 分子名称: | 6-[[3-(aminomethyl)phenyl]methylamino]pyridine-3-carboxamide, CITRIC ACID, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Hall, G, Cowan, R, Carr, M.D. | 登録日 | 2022-08-10 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors. Bioorg.Med.Chem.Lett., 90, 2023
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6BDG
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![BU of 6bdg by Molmil](/molmil-images/mine/6bdg) | HFQ monomer in spacegroup p6 at 1.93 angstrom resolution | 分子名称: | RNA-binding protein Hfq | 著者 | Brown, C, Zhang, K, Seo, C, Ellis, M.J, Hanniford, D.B, Junop, M. | 登録日 | 2017-10-23 | 公開日 | 2017-11-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.964 Å) | 主引用文献 | HFQ monomer in spacegroup p6 at 1.93 angstrom resolution To Be Published
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8APV
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![BU of 8apv by Molmil](/molmil-images/mine/8apv) | Crystal Structure of H. influenzae TrmD in complex with Compound 27 | 分子名称: | 1-[[4-(aminomethyl)phenyl]methyl]pyrrolo[2,3-b]pyridine-5-carboxamide, CITRIC ACID, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Hall, G, Cowan, R, Carr, M.D. | 登録日 | 2022-08-10 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors. Bioorg.Med.Chem.Lett., 90, 2023
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8APW
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![BU of 8apw by Molmil](/molmil-images/mine/8apw) | Crystal Structure of H. influenzae TrmD in complex with Compound 30 | 分子名称: | 1-[2-oxidanylidene-2-(piperidin-4-ylamino)ethyl]pyrrolo[2,3-b]pyridine-5-carboxamide, CITRIC ACID, tRNA (guanine-N(1)-)-methyltransferase | 著者 | Hall, G, Cowan, R, Carr, M.D. | 登録日 | 2022-08-10 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors. Bioorg.Med.Chem.Lett., 90, 2023
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6B9Y
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![BU of 6b9y by Molmil](/molmil-images/mine/6b9y) | Trastuzumab Fab v3 in complex with 5-phenyl meditope variant | 分子名称: | Immunoglobulin G binding protein A, Protein L, Trastuzumab Fab heavy chain, ... | 著者 | Bzymek, K.P, King, J.D, Williams, J.C. | 登録日 | 2017-10-11 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag. Bioconjug. Chem., 29, 2018
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6BBK
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4XUK
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