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5T7X
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Crystal structure of HHV-4 EBNA1 DNA binding domain (patient-derived, nasopharyngeal carcinoma) bound to DNA
分子名称: DNA (5'-D(*GP*GP*AP*TP*AP*GP*CP*CP*TP*AP*TP*GP*CP*TP*AP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*TP*AP*GP*CP*AP*TP*AP*GP*GP*CP*TP*AP*TP*CP*C)-3'), Epstein-Barr nuclear antigen 1
著者Malecka, K.A, Messick, T.E, Lieberman, P.M.
登録日2016-09-06
公開日2017-07-19
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Carcinoma-risk variant of EBNA1 deregulates Epstein-Barr Virus episomal latency.
Oncotarget, 8, 2017
3M7F
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BU of 3m7f by Molmil
Crystal structure of the Nedd4 C2/Grb10 SH2 complex
分子名称: E3 ubiquitin-protein ligase NEDD4, Growth factor receptor-bound protein 10
著者Huang, Q, Szebenyi, M.
登録日2010-03-16
公開日2010-10-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for the Interaction between the Growth Factor-binding Protein GRB10 and the E3 Ubiquitin Ligase NEDD4.
J.Biol.Chem., 285, 2010
2Q8F
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BU of 2q8f by Molmil
Structure of pyruvate dehydrogenase kinase isoform 1
分子名称: POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1
著者Kato, M, Li, J, Chuang, J.L, Chuang, D.T.
登録日2007-06-10
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol.
Structure, 15, 2007
3ME3
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BU of 3me3 by Molmil
Activator-Bound Structure of Human Pyruvate Kinase M2
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 3-{[4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-1,4-diazepan-1-yl]sulfonyl}aniline, Pyruvate kinase isozymes M1/M2, ...
著者Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC)
登録日2010-03-31
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis.
Nat.Chem.Biol., 8, 2012
3FEE
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BU of 3fee by Molmil
The high resolution structure of human glutamate carboxypeptidase III (GCPIII/NAALADase II) in complex with quisqualic acid
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lubkowski, J, Barinka, C, Hlouchova, K.
登録日2008-11-28
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III
Febs J., 276, 2009
1PU6
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BU of 1pu6 by Molmil
Crystal structure of H.pylori 3-methyladenine DNA glycosylase (MagIII)
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-METHYLADENINE DNA GLYCOSYLASE, BETA-MERCAPTOETHANOL, ...
著者Eichman, B.F, O'Rourke, E.J, Radicella, J.P, Ellenberger, T.
登録日2003-06-24
公開日2003-10-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases
Embo J., 22, 2003
3FED
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BU of 3fed by Molmil
The high resolution structure of human glutamate carboxypeptidase III (GCPIII/NAALADase II) in complex with a transition state analog of Glu-Glu
分子名称: (2S)-2-{[(S)-[(3S)-3-amino-3-carboxypropyl](hydroxy)phosphoryl]methyl}pentanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lubkowski, J, Barinka, C, Hlouchova, K.
登録日2008-11-28
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III
Febs J., 276, 2009
4LTP
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BU of 4ltp by Molmil
Bacterial sodium channel in high calcium, I222 space group, crystal 2
分子名称: CALCIUM ION, Ion transport protein
著者Shaya, D, Findeisen, F, Abderemane-Ali, F, Arrigoni, C, Wong, S, Reddy Nurva, S, Loussouarn, G, Minor, D.L.
登録日2013-07-23
公開日2013-10-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels.
J.Mol.Biol., 426, 2014
1Q35
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BU of 1q35 by Molmil
Crystal Structure of Pasteurella haemolytica Apo Ferric ion-Binding Protein A
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, iron binding protein FbpA
著者Shouldice, S.R, Dougan, D.R, Skene, R.J, Snell, G, Scheibe, D, Williams, P.A, Kirby, S, McRee, D.E, Schryvers, A.B, Tari, L.W.
登録日2003-07-28
公開日2003-11-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structure of Pasteurella haemolytica ferric ion-binding protein A reveals a novel class of bacterial iron-binding proteins
J.Biol.Chem., 278, 2003
1LR5
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BU of 1lr5 by Molmil
Crystal structure of auxin binding protein
分子名称: Auxin binding protein 1, ZINC ION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Woo, E.J, Marshall, J, Bauley, J, Chen, J.-G, Venis, M, Napier, R.M, Pickersgill, R.W.
登録日2002-05-14
公開日2002-06-19
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of auxin-binding protein 1 in complex with auxin.
EMBO J., 21, 2002
3MRU
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BU of 3mru by Molmil
Crystal Structure of Aminoacylhistidine Dipeptidase from Vibrio alginolyticus
分子名称: Aminoacyl-histidine dipeptidase, ZINC ION
著者Chang, C.-Y, Hsieh, Y.-C, Wu, T.-K, Chen, C.-J.
登録日2010-04-29
公開日2010-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure and mutational analysis of aminoacylhistidine dipeptidase from vibrio alginolyticus reveal a new architecture of M20 metallopeptidases
J.Biol.Chem., 285, 2010
2Q0E
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BU of 2q0e by Molmil
Terminal uridylyl transferase 4 from Trypanosoma brucei with bound GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA uridylyl transferase
著者Stagno, J, Luecke, H.
登録日2007-05-21
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q0D
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BU of 2q0d by Molmil
Terminal uridylyl transferase 4 from Trypanosoma brucei with bound ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA uridylyl transferase
著者Stagno, J, Luecke, H.
登録日2007-05-21
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Q8G
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BU of 2q8g by Molmil
Structure of pyruvate dehydrogenase kinase isoform 1 in complex with glucose-lowering drug AZD7545
分子名称: 4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE, POTASSIUM ION, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1
著者Kato, M, Li, J, Chuang, J.L, Chuang, D.T.
登録日2007-06-10
公開日2007-07-24
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Distinct Structural Mechanisms for Inhibition of Pyruvate Dehydrogenase Kinase Isoforms by AZD7545, Dichloroacetate, and Radicicol.
Structure, 15, 2007
5CTG
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BU of 5ctg by Molmil
The 3.1 A resolution structure of a eukaryotic SWEET transporter
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Bidirectional sugar transporter SWEET2b, ...
著者Tao, Y, Perry, K, Feng, L.
登録日2015-07-24
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.103 Å)
主引用文献Structure of a eukaryotic SWEET transporter in a homotrimeric complex.
Nature, 527, 2015
5CTH
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BU of 5cth by Molmil
The 3.7 A resolution structure of a eukaryotic SWEET transporter
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Bidirectional sugar transporter SWEET2b, ...
著者Feng, L, Tao, Y, Perry, K.
登録日2015-07-24
公開日2015-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.69 Å)
主引用文献Structure of a eukaryotic SWEET transporter in a homotrimeric complex.
Nature, 527, 2015
6CIP
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BU of 6cip by Molmil
Pyruvate:ferredoxin oxidoreductase from Moorella thermoacetica with acetyl-TPP bound
分子名称: 2-ACETYL-THIAMINE DIPHOSPHATE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ...
著者Chen, P.Y.-T, Drennan, C.L.
登録日2018-02-24
公開日2018-03-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.189 Å)
主引用文献Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase fromMoorella thermoacetica.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5T1O
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BU of 5t1o by Molmil
Solution-state NMR and SAXS structural ensemble of NPr (1-85) in complex with EIN-Ntr (170-424)
分子名称: Phosphocarrier protein NPr, Phosphoenolpyruvate-protein phosphotransferase PtsP
著者Strickland, M, Stanley, A.M, Wang, G, Schwieters, C.D, Buchanan, S, Peterkofsky, A, Tjandra, N.
登録日2016-08-19
公開日2016-11-16
最終更新日2024-05-15
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Structure of the NPr:EIN(Ntr) Complex: Mechanism for Specificity in Paralogous Phosphotransferase Systems.
Structure, 24, 2016
2PZZ
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BU of 2pzz by Molmil
2.2 A resolution crystal structure of UPF0201 protein from Methanococcus jannaschii
分子名称: UPF0201 protein MJ1564
著者Rao, K.N, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-05-18
公開日2007-05-29
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献UPF201 archaeal specific family members reveal structural similarity to RNA-binding proteins but low likelihood for RNA-binding function.
Plos One, 3, 2008
3MOS
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BU of 3mos by Molmil
The structure of human Transketolase
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, SODIUM ION, ...
著者Parthier, C, Tittmann, K.
登録日2010-04-23
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The crystal structure of human transketolase and new insights into its mode of action.
J.Biol.Chem., 285, 2010
6CIN
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BU of 6cin by Molmil
Crystal structure of pyruvate:ferredoxin oxidoreductase from Moorella thermoacetica
分子名称: IRON/SULFUR CLUSTER, MAGNESIUM ION, PYRUVATE-FERREDOXIN OXIDOREDUCTASE, ...
著者Chen, P.Y.-T, Drennan, C.L.
登録日2018-02-24
公開日2018-03-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase fromMoorella thermoacetica.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1NKX
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BU of 1nkx by Molmil
CRYSTAL STRUCTURE OF A PROTEOLYTICALLY GENERATED FUNCTIONAL MONOFERRIC C-LOBE OF BOVINE LACTOFERRIN AT 1.9A RESOLUTION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ...
著者Sharma, S, Jasti, J, Kumar, J, Mohanty, A.K, Singh, T.P.
登録日2003-01-06
公開日2003-09-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of a Proteolytically Generated Functional Monoferric C-lobe of Bovine Lactoferrin at 1.9A Resolution
J.Mol.Biol., 331, 2003
1KRH
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BU of 1krh by Molmil
X-ray Structure of Benzoate Dioxygenase Reductase
分子名称: Benzoate 1,2-Dioxygenase Reductase, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Karlsson, A, Beharry, Z.M, Eby, D.M, Coulter, E.D, Niedle, E.L, Kurtz Jr, D.M, Eklund, H, Ramaswamy, S.
登録日2002-01-09
公開日2002-05-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-ray crystal structure of benzoate 1,2-dioxygenase reductase from Acinetobacter sp. strain ADP1.
J.Mol.Biol., 318, 2002
6CIO
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BU of 6cio by Molmil
Pyruvate:ferredoxin oxidoreductase from Moorella thermoacetica with lactyl-TPP bound
分子名称: 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, IRON/SULFUR CLUSTER, MAGNESIUM ION, ...
著者Chen, P.Y.-T, Drennan, C.L.
登録日2018-02-24
公開日2018-03-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Binding site for coenzyme A revealed in the structure of pyruvate:ferredoxin oxidoreductase fromMoorella thermoacetica.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1KET
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The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Streptococcus suis with thymidine diphosphate bound
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, THYMIDINE-5'-DIPHOSPHATE, dTDP-D-glucose 4,6-dehydratase
著者Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H.
登録日2001-11-17
公開日2002-01-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Toward a structural understanding of the dehydratase mechanism.
Structure, 10, 2002

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