7PZY
| Structure of the vacant Candida albicans 80S ribosome | 分子名称: | 1,4-DIAMINOBUTANE, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Zgadzay, Y, Kolosova, O, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | 登録日 | 2021-10-13 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-08 | 実験手法 | ELECTRON MICROSCOPY (2.32 Å) | 主引用文献 | E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
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7Q0P
| Structure of the Candida albicans 80S ribosome in complex with anisomycin | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | 著者 | Kolosova, O, Zgadzay, Y, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | 登録日 | 2021-10-15 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-08 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
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7Q0F
| Structure of Candida albicans 80S ribosome in complex with phyllanthoside | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | 著者 | Zgadzay, Y, Kolosova, O, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | 登録日 | 2021-10-14 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-08 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
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7QDS
| Apo human SKI complex in the open state | 分子名称: | Helicase SKI2W, Tetratricopeptide repeat protein 37, WD repeat-containing protein 61 | 著者 | Koegel, A, Keidel, A, Bonneau, A, Schaefer, I.B, Conti, E. | 登録日 | 2021-11-30 | 公開日 | 2022-02-02 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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6WPW
| GCGR-Gs signaling complex bound to a designed glucagon derivative | 分子名称: | Glucagon derivative ZP3780, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Hilger, D, Krishna Kumar, K, Hu, H, Mathiesen, J.M, Skiniotis, G, Kobilka, B.K. | 登録日 | 2020-04-28 | 公開日 | 2020-08-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into differences in G protein activation by family A and family B GPCRs. Science, 369, 2020
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5LKS
| Structure-function insights reveal the human ribosome as a cancer target for antibiotics | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | 著者 | Myasnikov, A.G, Natchiar, S.K, Nebout, M, Hazemann, I, Imbert, V, Khatter, H, Peyron, J.-F, Klaholz, B.P. | 登録日 | 2016-07-23 | 公開日 | 2017-04-26 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure-function insights reveal the human ribosome as a cancer target for antibiotics. Nat Commun, 7, 2016
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7QEP
| Cryo-EM structure of the ribosome from Encephalitozoon cuniculi | 分子名称: | 18S ribosomal RNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... | 著者 | Nicholson, D, Ranson, N.A, Melnikov, S.V. | 登録日 | 2021-12-03 | 公開日 | 2022-02-09 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Adaptation to genome decay in the structure of the smallest eukaryotic ribosome Nat Commun, 13, 2022
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7QDY
| RNA-bound human SKI complex | 分子名称: | Helicase SKI2W, RNA (5'-R(P*UP*UP*UP*UP*UP*U)-3'), Tetratricopeptide repeat protein 37, ... | 著者 | Koegel, A, Keidel, A, Bonneau, F, Schaefer, I.B, Conti, E. | 登録日 | 2021-12-01 | 公開日 | 2022-02-09 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The human SKI complex regulates channeling of ribosome-bound RNA to the exosome via an intrinsic gatekeeping mechanism. Mol.Cell, 82, 2022
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6WZG
| Human secretin receptor Gs complex | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Piper, S.J, Belousoff, M.J, Danev, R. | 登録日 | 2020-05-13 | 公開日 | 2020-08-12 | 最終更新日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structure and dynamics of the active Gs-coupled human secretin receptor. Nat Commun, 11, 2020
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6WDR
| Subunit joining exposes nascent pre-40S rRNA for processing and quality control | 分子名称: | 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S10-A, ... | 著者 | Rai, J, Parker, M.D, Huang, H, Choy, S, Ghalei, H, Johnson, M.C, Karbstein, K, Stroupe, M.E. | 登録日 | 2020-04-01 | 公開日 | 2020-09-30 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7. Rna, 27, 2021
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6YLH
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5K0Y
| m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... | 著者 | Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. | 登録日 | 2016-05-17 | 公開日 | 2016-07-13 | 最終更新日 | 2018-04-18 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
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5JUP
| Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit) | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... | 著者 | Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. | 登録日 | 2016-05-10 | 公開日 | 2016-10-05 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
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6XA1
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6W2T
| Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the closed state (Class 2) | 分子名称: | 18S rRNA, CrPV 5'-UTR IRES, Eukaryotic translation initiation factor 3 subunit A, ... | 著者 | Neupane, R, Pisareva, V, Rodriguez, C.F, Pisarev, A, Fernandez, I.S. | 登録日 | 2020-03-08 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate. Elife, 9, 2020
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5JUU
| Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit) | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... | 著者 | Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. | 登録日 | 2016-05-10 | 公開日 | 2016-10-05 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
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6W18
| Structure of S. pombe Arp2/3 complex in inactive state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1, ... | 著者 | Shaaban, M, Nolen, B.J, Chowdhury, S. | 登録日 | 2020-03-03 | 公開日 | 2020-08-12 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state. Nat.Struct.Mol.Biol., 27, 2020
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5JUS
| Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure III (mid-rotated 40S subunit) | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... | 著者 | Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. | 登録日 | 2016-05-10 | 公開日 | 2016-10-05 | 最終更新日 | 2023-04-05 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
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6YAN
| Mammalian 48S late-stage translation initiation complex with histone 4 mRNA | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | 登録日 | 2020-03-12 | 公開日 | 2020-04-08 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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6YAM
| Mammalian 48S late-stage translation initiation complex (LS48S+eIF3 IC) with beta-globin mRNA | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ... | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | 登録日 | 2020-03-12 | 公開日 | 2020-04-08 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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6Y57
| Structure of human ribosome in hybrid-PRE state | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | 登録日 | 2020-02-25 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
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5LYB
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6YBS
| Structure of a human 48S translational initiation complex - head | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... | 著者 | Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. | 登録日 | 2020-03-17 | 公開日 | 2020-09-16 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of a human 48Stranslational initiation complex. Science, 369, 2020
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6YAL
| Mammalian 48S late-stage initiation complex with beta-globin mRNA | 分子名称: | 18S ribosomal RNA, 40S Ribosomal protein uS3, 40S Ribosomal protein uS7, ... | 著者 | Bochler, A, Simonetti, A, Guca, E, Hashem, Y. | 登録日 | 2020-03-12 | 公開日 | 2020-04-08 | 最終更新日 | 2020-04-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural Insights into the Mammalian Late-Stage Initiation Complexes. Cell Rep, 31, 2020
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6Y2L
| Structure of human ribosome in POST state | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | 登録日 | 2020-02-16 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
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