PDB: 35463 件ウェブページステータス検索Chemie searchBIRD

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6IEH	Crystal structures of the hMTR4-NRDE2 complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ... 著者 Chen, J.Y, Yun, C.H. 登録日 2018-09-14 公開日 2019-04-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.892 Å) 主引用文献 NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction. Genes Dev., 33, 2019
4V4V	Structure of a pre-translocational E. coli ribosome obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1056 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ... 著者 Mitra, K, Frank, J. 登録日 2006-05-09 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements Mol.Cell, 22, 2006
2QPW	Methyltransferase domain of human PR domain-containing protein 2 分子名称: PR domain zinc finger protein 2 著者 Lunin, V.V, Wu, H, Dombrovski, L, Antoshenko, T, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Plotnikov, A.N, Structural Genomics Consortium (SGC) 登録日 2007-07-25 公開日 2007-08-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structural biology of human H3K9 methyltransferases Plos One, 5, 2010
4V3O	Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. 分子名称: ACETATE ION, CALCIUM ION, YIII_M5_AII 著者 Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. 登録日 2014-10-20 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects Acta Crystallogr.,Sect.D, 72, 2016
4UUN	Trichomonas vaginalis lactate dehydrogenase in complex with NADH 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-LACTATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, Theobald, D.L. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
4XI7	Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with Jagged1 N-box peptide 分子名称: E3 ubiquitin-protein ligase MIB1, Jagged 1 N-box peptide, SULFATE ION, ... 著者 McMillan, B.J, Blacklow, S.C. 登録日 2015-01-06 公開日 2015-03-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.051 Å) 主引用文献 A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases. Mol.Cell, 57, 2015
3TWX	Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human FNBP1 (chimeric peptide) 分子名称: 1,2-ETHANEDIOL, HEXAETHYLENE GLYCOL, SULFATE ION, ... 著者 Guettler, S, Sicheri, F. 登録日 2011-09-22 公開日 2011-12-07 最終更新日 2011-12-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis and sequence rules for substrate recognition by tankyrase explain the basis for cherubism disease. Cell(Cambridge,Mass.), 147, 2011
4V27	Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with mannose-alpha-1,3-isofagomine 分子名称: 1,2-ETHANEDIOL, 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, GLYCOSYL HYDROLASE FAMILY 71, ... 著者 Hakki, Z, Bellmaine, S, Thompson, A.J, Speciale, G, Davies, G.J, Williams, S.J. 登録日 2014-10-07 公開日 2014-12-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Kinetic Dissection of the Endo-Alpha-1,2-Mannanase Activity of Bacterial Gh99 Glycoside Hydrolases from Bacteroides Spp. Chemistry, 21, 2015
4V2D	FLRT2 LRR domain 分子名称: FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2 著者 Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R. 登録日 2014-10-08 公開日 2014-11-05 最終更新日 2015-07-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development Neuron, 84, 2014
4V41	E. COLI (LAC Z) BETA-GALACTOSIDASE (NCS CONSTRAINED MONOMER-MONOCLINIC) 分子名称: BETA-GALACTOSIDASE, MAGNESIUM ION 著者 Juers, D.H, Jacobson, R.H, Wigley, D, Zhang, X.J, Huber, R.E, Tronrud, D.E, Matthews, B.W. 登録日 2000-06-07 公開日 2014-07-09 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 High resolution refinement of beta-galactosidase in a new crystal form reveals multiple metal-binding sites and provides a structural basis for alpha-complementation. Protein Sci., 9, 2000
5YC2	Crystal structure of inner membrane protein Bqt4 in complex with telomeric protein Rap1 分子名称: DNA-binding protein rap1, Ubiquitin-like protein SMT3,Bouquet formation protein 4 著者 Chen, Y, Hu, C. 登録日 2017-09-06 公開日 2018-11-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.704 Å) 主引用文献 Structural insights into chromosome attachment to the nuclear envelope by an inner nuclear membrane protein Bqt4 in fission yeast. Nucleic Acids Res., 47, 2019
5YDG	Crystal structure of the Arabidopsis thaliana chloroplast RNA editing factors 2(MORF2) 分子名称: Multiple organellar RNA editing factor 2, chloroplastic 著者 Wang, X, Yang, J.Y, Wang, Y.L, Gao, Y.S. 登録日 2017-09-13 公開日 2017-12-20 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.405 Å) 主引用文献 Crystal structure of the chloroplast RNA editing factor MORF2 Biochem. Biophys. Res. Commun., 495, 2018
4WDW	17beta-HSD5 in complex with 3,6-dihydropyridin-1(2H)-yl(5-methyl-1H-indol-2-yl)methanone 分子名称: 3,6-dihydropyridin-1(2H)-yl(5-methyl-1H-indol-2-yl)methanone, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Amano, Y, Yamaguchi, T. 登録日 2014-09-09 公開日 2015-04-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structures of complexes of type 5 17 beta-hydroxysteroid dehydrogenase with structurally diverse inhibitors: insights into the conformational changes upon inhibitor binding. Acta Crystallogr.,Sect.D, 71, 2015
4UYM	Crystal structure of sterol 14-alpha demethylase (CYP51B) from a pathogenic filamentous fungus Aspergillus fumigatus in complex with voriconazole 分子名称: 14-ALPHA STEROL DEMETHYLASE, PROTOPORPHYRIN IX CONTAINING FE, Voriconazole 著者 Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. 登録日 2014-09-02 公開日 2015-08-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure-Functional Characterization of Cytochrome P450 Sterol Alpha-Demethylase (Cyp51B) from Aspergillus Fumigatus and Molecular Basis for the Development of Antifungal Drugs J.Biol.Chem., 290, 2015
4N6X	Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1 分子名称: CHLORIDE ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1/Chemokine Receptor CXCR2 fusion protein 著者 Lu, G, Wu, Y, Jiang, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z. 登録日 2013-10-14 公開日 2014-01-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.051 Å) 主引用文献 New Conformational State of NHERF1-CXCR2 Signaling Complex Captured by Crystal Lattice Trapping. Plos One, 8, 2013
5YIU	Caulobacter crescentus GcrA DNA-binding domain (DBD) 分子名称: Cell cycle regulatory protein GcrA 著者 Wu, X, Zhang, Y. 登録日 2017-10-06 公開日 2018-03-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA. Nucleic Acids Res., 46, 2018
5YIW	Caulobacter crescentus GcrA DNA-binding domain (DBD) in complex with methylated dsDNA (crystal form 2) 分子名称: (R,R)-2,3-BUTANEDIOL, Cell cycle regulatory protein GcrA, DNA (5'-D(*CP*CP*CP*TP*GP*(6MA)P*TP*TP*CP*GP*C)-3'), ... 著者 Wu, X, Zhang, Y. 登録日 2017-10-06 公開日 2018-03-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.551 Å) 主引用文献 Structural insights into the unique mechanism of transcription activation by Caulobacter crescentus GcrA. Nucleic Acids Res., 46, 2018
4W52	T4 Lysozyme L99A with Benzene Bound 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BENZENE, Endolysin 著者 Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. 登録日 2014-08-16 公開日 2015-04-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5001 Å) 主引用文献 Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
4W54	T4 Lysozyme L99A with Ethylbenzene Bound 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, PHENYLETHANE 著者 Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. 登録日 2014-08-16 公開日 2015-04-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7901 Å) 主引用文献 Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
4W57	T4 Lysozyme L99A with n-Butylbenzene Bound 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, N-BUTYLBENZENE 著者 Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. 登録日 2014-08-16 公開日 2015-04-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6801 Å) 主引用文献 Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
4XIB	Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with fly Delta N-box peptide 分子名称: Delta N-box peptide, E3 ubiquitin-protein ligase MIB1, SULFATE ION, ... 著者 McMillan, B.J, Blacklow, S.C. 登録日 2015-01-06 公開日 2015-03-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.147 Å) 主引用文献 A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases. Mol.Cell, 57, 2015
4W8F	Crystal structure of the dynein motor domain in the AMPPNP-bound state 分子名称: Dynein heavy chain lysozyme chimera, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Cheng, H.-C, Bhabha, G, Zhang, N, Vale, R.D. 登録日 2014-08-24 公開日 2014-11-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.541 Å) 主引用文献 Allosteric communication in the Dynein motor domain. Cell, 159, 2014
3UA9	Crystal structure of human tankyrase 2 in complex with a selective inhibitor 分子名称: 4-[(3aR,4S,7R,7aS)-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... 著者 Narwal, M, Lehtio, L. 登録日 2011-10-21 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis of selective inhibition of human tankyrases. J.Med.Chem., 55, 2012
4V2C	mouse FLRT2 LRR domain in complex with rat Unc5D Ig1 domain 分子名称: FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2, PROTEIN UNC5D 著者 Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R. 登録日 2014-10-08 公開日 2014-11-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development Neuron, 84, 2014
4UTN	Crystal structure of zebrafish Sirtuin 5 in complex with succinylated CPS1-peptide 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, ... 著者 Pannek, M, Gertz, M, Steegborn, C. 登録日 2014-07-21 公開日 2014-08-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Chemical Probing of the Human Sirtuin 5 Active Site Reveals its Substrate Acyl Specificity and Peptide-Based Inhibitors. Angew.Chem.Int.Ed.Engl., 53, 2014

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