4XI7

Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with Jagged1 N-box peptide

Summary for 4XI7

• Entry DOI: 10.2210/pdb4xi7/pdb
• Related: 4XFX 4XIB
• Descriptor: E3 ubiquitin-protein ligase MIB1, Jagged 1 N-box peptide, ZINC ION, ... (5 entities in total)
• Functional Keywords: e3 ligase, notch signaling, ligase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 43751.54

Authors

McMillan, B.J.,Blacklow, S.C. (deposition date: 2015-01-06, release date: 2015-03-18, Last modification date: 2024-02-28)

• Primary citation: McMillan, B.J.,Schnute, B.,Ohlenhard, N.,Zimmerman, B.,Miles, L.,Beglova, N.,Klein, T.,Blacklow, S.C.; A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.; Mol.Cell, 57:912-924, 2015; PubMed: 25747658; DOI: 10.1016/j.molcel.2015.01.019

Experimental method

X-RAY DIFFRACTION (2.051 Å)