PDB: 13258 件ウェブページステータス検索Chemie searchBIRD

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6AX3	Complex structure of JMJD5 and Symmetric Dimethyl-Arginine (SDMA) 分子名称: 2-OXOGLUTARIC ACID, Lysine-specific demethylase 8, N3, ... 著者 Lee, S, Liu, H, Wang, Y, Dai, S, Zhang, G. 登録日 2017-09-06 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. Sci Rep, 8, 2018
5Y39	Crystal structure of Ragulator complex (p18 76-145) 分子名称: Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... 著者 Zhang, T, Ding, J. 登録日 2017-07-28 公開日 2017-12-06 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1 Nat Commun, 8, 2017
5UFS	X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with triamcinolone acetonide and SHP coregulator fragment 分子名称: Ancestral Glucocorticoid Receptor2, SHP NR Box 1 Peptide, Triamcinolone acetonide 著者 Weikum, E.R, Ortlund, E.A. 登録日 2017-01-05 公開日 2017-04-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.118 Å) 主引用文献 Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner. Mol. Pharmacol., 92, 2017
5YDE	Crystal structure of a disease-related gene, hCDC73(1-111) 分子名称: Parafibromin 著者 Sun, W, Kuang, X.L, Liu, Y.P, Tian, L.F, Yan, X.X, Xu, W.Q. 登録日 2017-09-13 公開日 2017-12-20 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.023 Å) 主引用文献 Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome Sci Rep, 7, 2017
6B9X	Crystal structure of Ragulator 分子名称: Hepatitis B virus x interacting protein, Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, ... 著者 SU, M.-Y, Hurley, J.H. 登録日 2017-10-11 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex. Mol. Cell, 68, 2017
6B76	Crystal Structure of human NAMPT in complex with NVP-LVR596 分子名称: (1S,2S)-N-{4-[(1S)-1-(propanoylamino)ethyl]phenyl}-2-(pyridin-3-yl)cyclopropane-1-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION 著者 Weihofen, W.A, Thigale, S. 登録日 2017-10-03 公開日 2018-10-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Identification and structure based design of cellularly active cyclo-propyl carboxamide Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors To Be Published
5YBC	X-ray structure of native ETS-domain domain of Ergp55 分子名称: GLYCEROL, Transcriptional regulator ERG 著者 Saxena, A.K, Gangwar, S.P. 登録日 2017-09-04 公開日 2018-09-19 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence Acta Crystallogr F Struct Biol Commun, 74, 2018
7E0Z	Crystal structure of PKAc-PLN complex 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PLN, ... 著者 Qin, J, Yuchi, Z. 登録日 2021-01-28 公開日 2022-04-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.162 Å) 主引用文献 Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy. Elife, 11, 2022
7E12	Crystal structure of PKAc-A11E complex 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, THR-ARG-SER-GLU-ILE-ARG-ARG-ALA-SER-THR-ILE-GLU, ... 著者 Qin, J, Lin, L, Yuchi, Z. 登録日 2021-01-28 公開日 2022-04-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.796 Å) 主引用文献 Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy. Elife, 11, 2022
7E11	Crystal structure of PKAc-PLN R9C complex 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PLN, ... 著者 Qin, J, Lin, L, Yuchi, Z. 登録日 2021-01-28 公開日 2022-04-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.43 Å) 主引用文献 Structures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy. Elife, 11, 2022
2XKO	Crystal structure of the complex of NtcA with its transcriptional co- activator PipX 分子名称: 2-OXOGLUTARIC ACID, GLOBAL NITROGEN REGULATOR, PIPX 著者 Llacer, J.L, Castells, M.A, Rubio, V. 登録日 2010-07-11 公開日 2010-08-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural Basis for the Regulation of Ntca-Dependent Transcription by Proteins Pipx and Pii. Proc.Natl.Acad.Sci.USA, 107, 2010
5TUT	UbcH5a-Ub isopeptide conjugate 分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 D1 著者 Sanchez, J.G, Wagner, J.M, Pornillos, O. 登録日 2016-11-07 公開日 2017-11-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.604 Å) 主引用文献 UbcH5a-Ub isopeptide conjugate To be Published
8F36	Ubx Homeodomain NMR solution structure 分子名称: Homeotic protein ultrabithorax 著者 Beasley, S.A, Loss, J.W, Mekkaoui, F, Advocate, M.R, Spratt, D.E. 登録日 2022-11-09 公開日 2023-04-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Ubx Homeodomain NMR solution structure To Be Published
8F37	AbdA Homeodomain NMR Solution Structure 分子名称: Homeobox protein abdominal-A 著者 Beasley, S.A, Simons, R.A, Advocate, M.R, Mekkaoui, F, Spratt, D.E. 登録日 2022-11-09 公開日 2023-04-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 AbdA Homeodomain NMR solution structure To Be Published
5YJ8	Identification of a small molecule inhibitor for the Tudor domain of TDRD3 分子名称: 5-(aminomethyl)-1,3-dimethyl-benzimidazol-2-one, SULFATE ION, Tudor domain-containing protein 3 著者 Liu, J, Ruan, K. 登録日 2017-10-09 公開日 2018-05-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.762 Å) 主引用文献 Structural plasticity of the TDRD3 Tudor domain probed by a fragment screening hit. FEBS J., 285, 2018
2XPB	DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION 分子名称: 5-[BENZYL(METHYL)CARBAMOYL]-2-(3-CHLOROPHENYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, DODECAETHYLENE GLYCOL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 著者 Potter, A, Oldfield, V, Nunns, C, Fromont, C, Ray, S, Northfield, C.J, Bryant, C.J, Scrace, S.F, Robinson, D, Matossova, N, Baker, L, Dokurno, P, Surgenor, A.E, Davis, B.E, Richardson, C.M, Murray, J.B, Moore, J.D. 登録日 2010-08-25 公開日 2011-01-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of Cell-Active Phenyl-Imidazole Pin1 Inhibitors by Structure-Guided Fragment Evolution. Bioorg.Med.Chem.Lett., 20, 2010
5U2M	Crystal structure of human NAMPT with A-1293201 分子名称: N-[4-({[(3S)-oxolan-3-yl]methyl}carbamoyl)phenyl]-1,3-dihydro-2H-isoindole-2-carboxamide, Nicotinamide phosphoribosyltransferase, SULFATE ION 著者 Longenecker, K.L, Raich, D, Korepanova, A.V. 登録日 2016-11-30 公開日 2017-06-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors. Mol. Cancer Ther., 16, 2017
6VBU	Structure of the bovine BBSome complex 分子名称: BBS1 domain-containing protein, Bardet-Biedl syndrome 18 protein, Bardet-Biedl syndrome 2 protein homolog, ... 著者 Singh, S.K, Gui, M, Koh, F, Yip, M.C.J, Brown, A. 登録日 2019-12-19 公開日 2020-01-29 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure and activation mechanism of the BBSome membrane protein trafficking complex. Elife, 9, 2020
8EQG	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAA(DU)GGAAGTGGG) 分子名称: DNA (5'-D(*AP*AP*DU*AP*AP*AP*TP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-10-07 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EKV	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGATGTGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*TP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*AP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-22 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8EM9	Human PU.1 ETS-Domain (165-270) Bound to d(AATAGGAGAAGTAGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*GP*GP*AP*GP*AP*AP*GP*TP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*TP*AP*CP*TP*TP*CP*TP*CP*CP*TP*A)-3'), Transcription factor PU.1 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-27 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.341 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
8ENG	Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGCGGAAGTGGG) with Hemi-methylated CpG (forward strand) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*G*(5CM)P*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-29 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023
2XYI	Crystal Structure of Nurf55 in complex with a H4 peptide 分子名称: DI(HYDROXYETHYL)ETHER, HISTONE H4, PROBABLE HISTONE-BINDING PROTEIN CAF1, ... 著者 Stirnimann, C.U, Nowak, A.J, Mueller, C.W. 登録日 2010-11-17 公開日 2011-05-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Chromatin-Modifying Complex Component Nurf55/P55 Associates with Histones H3, H4 and Polycomb Repressive Complex 2 Subunit Su(Z)12 Through Partially Overlapping Binding Sites. J.Biol.Chem., 286, 2011
6VGD	Crystal structure of the DNA binding domain (DBD) of human FLI1 and the complex of the DBD of human Runx2 with core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC 分子名称: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... 著者 Hou, C, Tsodikov, O.V. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
8EK3	Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAATGGGG) 分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), SODIUM ION, ... 著者 Terrell, J.R, Poon, G.M.K. 登録日 2022-09-19 公開日 2023-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 DNA selection by the master transcription factor PU.1. Cell Rep, 42, 2023

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