8EK3

Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAAGCGGAATGGGG)

Summary for 8EK3

• Entry DOI: 10.2210/pdb8ek3/pdb
• Related: 8E3K 8E3R 8E4H 8E5Y 8EBH 8EE9 8EJ6 8EJ8
• Descriptor: DNA (5'-D(*AP*AP*TP*AP*AP*GP*CP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*GP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1, ... (5 entities in total)
• Functional Keywords: transcription factor, protein-dna complex, ets family, ets, pu.1, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 22256.94

Authors

Terrell, J.R.,Poon, G.M.K. (deposition date: 2022-09-19, release date: 2023-07-05, Last modification date: 2023-10-25)

• Primary citation: Terrell, J.R.,Taylor, S.J.,Schneider, A.L.,Lu, Y.,Vernon, T.N.,Xhani, S.,Gumpper, R.H.,Luo, M.,Wilson, W.D.,Steidl, U.,Poon, G.M.K.; DNA selection by the master transcription factor PU.1.; Cell Rep, 42:112671-112671, 2023; PubMed: 37352101; DOI: 10.1016/j.celrep.2023.112671

Experimental method

X-RAY DIFFRACTION (1.38 Å)