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5YJ8

Identification of a small molecule inhibitor for the Tudor domain of TDRD3

Summary for 5YJ8
Entry DOI10.2210/pdb5yj8/pdb
DescriptorTudor domain-containing protein 3, 5-(aminomethyl)-1,3-dimethyl-benzimidazol-2-one, SULFATE ION, ... (4 entities in total)
Functional Keywordstranscriptional coactivator, complex, inhibitor, transcription-inhibitor complex, transcription/inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight7434.38
Authors
Liu, J.,Ruan, K. (deposition date: 2017-10-09, release date: 2018-05-02, Last modification date: 2023-11-22)
Primary citationLiu, J.,Zhang, S.,Liu, M.,Liu, Y.,Nshogoza, G.,Gao, J.,Ma, R.,Yang, Y.,Wu, J.,Zhang, J.,Li, F.,Ruan, K.
Structural plasticity of the TDRD3 Tudor domain probed by a fragment screening hit.
FEBS J., 285:2091-2103, 2018
Cited by
PubMed: 29645362
DOI: 10.1111/febs.14469
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.762 Å)
Structure validation

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