1JI0
 
 | | Crystal Structure Analysis of the ABC transporter from Thermotoga maritima | | 分子名称: | ABC transporter, ADENOSINE-5'-TRIPHOSPHATE | | 著者 | Zhang, R, Joachimiak, A, Edwards, A, Savchenko, A, Beasley, S, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2001-06-28 | | 公開日 | 2002-08-14 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The 2.0 A Crystal Structure of ABC Transporter from Thermotoga maritima
TO BE PUBLISHED
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2DK2
 | | Solution structure of RRM domain in heterogeneous nuclear ribonucleoprotein R (hnRNP R) | | 分子名称: | Heterogeneous nuclear ribonucleoprotein R | | 著者 | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-06 | | 公開日 | 2006-10-06 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of RRM domain in heterogeneous nuclear ribonucleoprotein R (hnRNP R)
To be Published
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2DGT
 | | Solution structure of the second RNA binding domain in RNA-binding protein 30 | | 分子名称: | RNA-binding protein 30 | | 著者 | Abe, C, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-03-15 | | 公開日 | 2006-09-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the second RNA binding domain in RNA-binding protein 30
To be Published
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2W05
 | | Structure of CDK2 in complex with an imidazolyl pyrimidine, compound 5b | | 分子名称: | CELL DIVISION PROTEIN KINASE 2, N-(2-METHOXYETHYL)-4-({4-[2-METHYL-1-(1-METHYLETHYL)-1H-IMIDAZOL-5-YL]PYRIMIDIN-2-YL}AMINO)BENZENESULFONAMIDE | | 著者 | Anderson, M, Andrews, D.M, Barker, A.J, Brassington, C.A, Breed, J, Byth, K.F, Culshaw, J.D, Finlay, M.R, Fisher, E, Green, C.P, Heaton, D.W, Nash, I.A, Newcombe, N.J, Oakes, S.E, Pauptit, R.A, Roberts, A, Stanway, J.J, Thomas, A.P, Tucker, J.A, Weir, H.M. | | 登録日 | 2008-08-08 | | 公開日 | 2008-10-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Imidazoles: Sar and Development of a Potent Class of Cyclin-Dependent Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
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2DKM
 | | Solution structures of the fn3 domain of human collagen alpha-1(XX) chain | | 分子名称: | Collagen alpha-1(XX) chain | | 著者 | Sato, M, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-12 | | 公開日 | 2006-10-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures of the fn3 domain of human collagen alpha-1(XX) chain
To be Published
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2DH9
 | | Solution structure of the C-terminal RNA binding domain in Heterogeneous nuclear ribonucleoprotein M | | 分子名称: | Heterogeneous nuclear ribonucleoprotein M | | 著者 | Ochi, T, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-03-23 | | 公開日 | 2006-09-23 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the C-terminal RNA binding domain in Heterogeneous nuclear ribonucleoprotein M
To be Published
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3HMM
 | | Structure of Alk5 + GW855857 | | 分子名称: | 2-(6-methylpyridin-2-yl)-N-pyridin-4-ylquinazolin-4-amine, TGF-beta receptor type-1 | | 著者 | Smith, W, Janson, C. | | 登録日 | 2009-05-29 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors
Bioorg.Med.Chem.Lett., 19, 2009
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3A7H
 | | Human MST3 kinase in complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Serine/threonine kinase 24 (STE20 homolog, yeast) | | 著者 | Ko, T.P, Jeng, W.Y, Liu, C.I, Lai, M.D, Wang, A.H.J. | | 登録日 | 2009-09-26 | | 公開日 | 2010-02-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structures of human MST3 kinase in complex with adenine, ADP and Mn2+.
Acta Crystallogr.,Sect.D, 66, 2010
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1JK1
 | | Zif268 D20A Mutant Bound to WT DNA Site | | 分子名称: | 5'-D(*AP*GP*CP*GP*TP*GP*GP*GP*CP*GP*G)-3', 5'-D(*TP*CP*CP*GP*CP*CP*CP*AP*CP*GP*C)-3', ZIF268, ... | | 著者 | Miller, J.C, Pabo, C.O. | | 登録日 | 2001-07-11 | | 公開日 | 2001-10-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Rearrangement of side-chains in a Zif268 mutant highlights the complexities of zinc finger-DNA recognition.
J.Mol.Biol., 313, 2001
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2DMT
 | | Solution structure of the homeobox domain of Homeobox protein BarH-like 1 | | 分子名称: | Homeobox protein BarH-like 1 | | 著者 | Ohnishi, S, Yoneyama, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-04-24 | | 公開日 | 2006-10-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the homeobox domain of Homeobox protein BarH-like 1
To be Published
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2DIS
 | | Solution structure of the RRM domain of unnamed protein product | | 分子名称: | unnamed protein product | | 著者 | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2006-03-30 | | 公開日 | 2006-09-30 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the RRM domain of unnamed protein product
To be Published
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1JBE
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2DPX
 | | Crystal Structure of human Rad GTPase | | 分子名称: | GTP-binding protein RAD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | | 著者 | Yanuar, A, Sakurai, S, Kitano, K, Hakoshima, T. | | 登録日 | 2006-05-18 | | 公開日 | 2006-08-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of human Rad GTPase of the RGK-family
Genes Cells, 11, 2006
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1JBP
 | | Crystal Structure of the Catalytic Subunit of cAMP-dependent Protein Kinase Complexed with a Substrate Peptide, ADP and Detergent | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR, MUSCLE/BRAIN FORM, ... | | 著者 | Madhusudan, Trafny, E.A, Xuong, N.H, Adams, J.A, Ten Eyck, L.F, Taylor, S.S, Sowadski, J.M. | | 登録日 | 2001-06-06 | | 公開日 | 2001-06-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | cAMP-dependent protein kinase: crystallographic insights into substrate recognition and phosphotransfer.
Protein Sci., 3, 1994
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1WAV
 | | CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN | | 分子名称: | INSULIN, PHENOL, ZINC ION | | 著者 | Liang, D.-C, Ding, J.-H, Chang, W.-R, Wan, Z.-L. | | 登録日 | 1996-02-28 | | 公開日 | 1997-02-28 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular replacement study on form-B monoclinic crystal of insulin.
Sci.China, Ser.C: Life Sci., 39, 1996
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1JCA
 | | Non-standard Design of Unstable Insulin Analogues with Enhanced Activity | | 分子名称: | ZINC ION, insulin a, insulin b | | 著者 | Weiss, M.A, Wan, Z, Zhao, M, Chu, Y.-C, Nakagawa, S.H, Burke, G.T, Jia, W, Hellmich, R, Katsoyannis, P.G. | | 登録日 | 2001-06-08 | | 公開日 | 2001-06-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor.
J.Mol.Biol., 315, 2002
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1UVR
 | | Structure of human PDK1 kinase domain in complex with BIM-8 | | 分子名称: | 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, 3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, GLYCEROL, ... | | 著者 | Komander, D, Garrido-Franco, M, Kular, G.S, Schuttelkopf, A.W, Deak, M, Prakash, K.R, Bain, J, Elliot, M, Kozikowski, A.P, Alessi, D.R, Van Aalten, D.M.F. | | 登録日 | 2004-01-22 | | 公開日 | 2004-03-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1
Structure, 12, 2004
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2XK7
 | | Structure of Nek2 bound to aminopyrazine compound 23 | | 分子名称: | (3R,4R)-1-[3-amino-6-(3,4,5-trimethoxyphenyl)pyrazin-2-yl]-3-ethylpiperidine-4-carboxylic acid, CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2 | | 著者 | Mas-Droux, C, Bayliss, R. | | 登録日 | 2010-07-07 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.992 Å) | | 主引用文献 | Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: Sar and Structural Characterization.
J.Med.Chem., 53, 2010
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2DN1
 | | 1.25A resolution crystal structure of human hemoglobin in the oxy form | | 分子名称: | Hemoglobin alpha subunit, Hemoglobin beta subunit, OXYGEN MOLECULE, ... | | 著者 | Park, S.-Y, Yokoyama, T, Shibayama, N, Shiro, Y, Tame, J.R. | | 登録日 | 2006-04-25 | | 公開日 | 2006-05-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | 1.25 a resolution crystal structures of human haemoglobin in the oxy, deoxy and carbonmonoxy forms.
J.Mol.Biol., 360, 2006
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1JL9
 | | Crystal Structure of Human Epidermal Growth Factor | | 分子名称: | EPIDERMAL GROWTH FACTOR | | 著者 | Lu, H.S, Chai, J.J, Li, M, Huang, B.R, He, C.H, Bi, R.C. | | 登録日 | 2001-07-16 | | 公開日 | 2001-10-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of human epidermal growth factor and its dimerization
J.Biol.Chem., 276, 2001
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1TNI
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2XNG
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1JLT
 | | Vipoxin Complex | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, PHOSPHOLIPASE A2, ... | | 著者 | Banumathi, S, Rajashankar, K.R, Notzel, C, Aleksiev, B, Singh, T.P, Genov, N, Betzel, C. | | 登録日 | 2001-07-16 | | 公開日 | 2001-10-31 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of the neurotoxic complex vipoxin at 1.4 A resolution.
Acta Crystallogr.,Sect.D, 57, 2001
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1UU3
 | | Structure of human PDK1 kinase domain in complex with LY333531 | | 分子名称: | (9R)-9-[(DIMETHYLAMINO)METHYL]-6,7,10,11-TETRAHYDRO-9H,18H-5,21:12,17-DIMETHENODIBENZO[E,K]PYRROLO[3,4-H][1,4,13]OXADIA ZACYCLOHEXADECINE-18,20-DIONE, 3-PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE-1, GLYCEROL, ... | | 著者 | Komander, D, Kular, G.S, Schuttelkopf, A.W, Deak, M, Prakash, K.R, Bain, J, Elliot, M, Garrido-Franco, M, Kozikowski, A.P, Alessi, D.R, Van Aalten, D.M.F. | | 登録日 | 2003-12-15 | | 公開日 | 2004-03-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Interactions of Ly333531 and Other Bisindolyl Maleimide Inhibitors with Pdk1
Structure, 12, 2004
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1UXL
 | | I113T mutant of human SOD1 | | 分子名称: | COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ... | | 著者 | Hough, M.A, Grossmann, J.G, Antonyuk, S.V, Strange, R.W, Doucette, P.A, Rodriguez, J.A, Whitson, L.J, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S. | | 登録日 | 2004-02-25 | | 公開日 | 2004-03-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Dimer Destabilization in Superoxide Dismutase May Result in Disease-Causing Properties: Structures of Motor Neuron Disease Mutants
Proc.Natl.Acad.Sci.USA, 101, 2004
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