Crystal Structure of Human Epidermal Growth Factor

Summary for 1JL9

DescriptorEPIDERMAL GROWTH FACTOR (2 entities in total)
Functional Keywordsdimerization, growth factor, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein P01133
Total number of polymer chains2
Total molecular weight11917.35
Lu, H.S.,Chai, J.J.,Li, M.,Huang, B.R.,He, C.H.,Bi, R.C. (deposition date: 2001-07-16, release date: 2001-10-24, Last modification date: 2011-07-13)
Primary citation
Lu, H.S.,Chai, J.J.,Li, M.,Huang, B.R.,He, C.H.,Bi, R.C.
Crystal structure of human epidermal growth factor and its dimerization
J.Biol.Chem., 276:34913-34917, 2001
PubMed: 11438527 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M102874200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26017 4.8% 21.3% 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25