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4LJP
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BU of 4ljp by Molmil
Structure of an active ligase (HOIP-H889A)/ubiquitin transfer complex
分子名称: E3 ubiquitin-protein ligase RNF31, Polyubiquitin-C, ZINC ION
著者Rana, R.R, Stieglitz, B, Koliopoulos, M.G, Morris-Davies, A.C, Christodoulou, E, Howell, S, Brown, N.R, Rittinger, K.
登録日2013-07-05
公開日2013-10-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Nature, 503, 2013
2MA9
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BU of 2ma9 by Molmil
HIV-1 Vif SOCS-box and Elongin BC solution structure
分子名称: Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, Virion infectivity factor
著者Lu, Z, Bergeron, J.R, Atkinson, R.A, Schaller, T, Veselkov, D.A, Oregioni, A, Yang, Y, Matthews, S.J, Malim, M.H, Sanderson, M.R.
登録日2013-07-01
公開日2013-12-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction.
OPEN BIOLOGY, 3, 2013
4BVU
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BU of 4bvu by Molmil
Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate
分子名称: PROTEIN KINASE OSPG, UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2 D3
著者Pruneda, J.N, LeTrong, I, Stenkamp, R.E, Klevit, R.E, Brzovic, P.S.
登録日2013-06-28
公開日2014-01-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis.
Embo J., 33, 2014
4LDT
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BU of 4ldt by Molmil
The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ...
著者Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C.
登録日2013-06-25
公開日2013-08-14
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
Nat.Struct.Mol.Biol., 20, 2013
4LCD
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BU of 4lcd by Molmil
Structure of an Rsp5xUbxSna3 complex: Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
分子名称: E3 ubiquitin-protein ligase RSP5, Protein SNA3, Ubiquitin
著者Kamadurai, H.B, Miller, D, Schulman, B.A.
登録日2013-06-21
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3.
Elife, 2, 2013
2M8S
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BU of 2m8s by Molmil
NMR Structure of the Cytoplasmic Tail of the Membrane Form of Heparin-binding EGF-like Growth Factor (proHB-EGF-CT) Complexed with the Ubiquitin Homology Domain of Bcl-2-associated Athanogene 1 from Mus musculus (mBAG-1-UBH)
分子名称: BAG family molecular chaperone regulator 1, Proheparin-binding EGF-like growth factor
著者Huang, H.W, Yu, C.
登録日2013-06-03
公開日2014-04-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Structure of the Cytoplasmic Tail of Heparin Binding EGF-like Growth Factor (proHB-EGF-CT) Complexed with the Ubiquitin Homology Domain of Bcl-2-Associated Athanogene 1 from Mus musculus (mBAG-1-UBH).
Biochemistry, 53, 2014
4KZZ
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BU of 4kzz by Molmil
Rabbit 40S ribosomal subunit in complex with mRNA, initiator tRNA and eIF1A
分子名称: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
著者Lomakin, I.B, Steitz, T.A.
登録日2013-05-30
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (7.0305 Å)
主引用文献The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4KZX
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BU of 4kzx by Molmil
Rabbit 40S ribosomal subunit in complex with eIF1.
分子名称: 18S ribosomal RNA, 40S Ribosomal protein S9, 40S ribosomal protein RACK1, ...
著者Lomakin, I.B, Steitz, T.A.
登録日2013-05-30
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (7.809 Å)
主引用文献The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4KZY
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BU of 4kzy by Molmil
Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A.
分子名称: 18S Ribosomal RNA, 40S Ribosomal Protein RACK1, 40S Ribosomal Protein S10, ...
著者Lomakin, I.B, Steitz, T.A.
登録日2013-05-30
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (7.01 Å)
主引用文献The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Nature, 500, 2013
4BOZ
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BU of 4boz by Molmil
Structure of OTUD2 OTU domain in complex with K11-linked di ubiquitin
分子名称: GLYCEROL, UBIQUITIN THIOESTERASE OTU1, UBIQUITIN-C
著者Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2013-05-22
公開日2013-07-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4BOS
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BU of 4bos by Molmil
Structure of OTUD2 OTU domain in complex with Ubiquitin K11-linked peptide
分子名称: MAGNESIUM ION, NITRATE ION, OTUD2, ...
著者Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2013-05-22
公開日2013-07-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
4KSK
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BU of 4ksk by Molmil
Gumby/Fam105B in complex with ubiquitin
分子名称: Polyubiquitin-C, Protein FAM105B, SULFATE ION
著者Ceccarelli, D.F, Juang, Y.-C, Sicheri, F.
登録日2013-05-17
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
4KSL
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BU of 4ksl by Molmil
Gumby/Fam105B in complex with linear di-ubiquitin
分子名称: Polyubiquitin-C, Protein FAM105B
著者Juang, Y.-C, Ceccarelli, D.F, Sicheri, F.
登録日2013-05-17
公開日2013-06-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
4BKT
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BU of 4bkt by Molmil
von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide
分子名称: (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ARGININE, GLUTAMIC ACID, ...
著者Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A.
登録日2013-04-29
公開日2013-11-27
最終更新日2017-07-12
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions?
Acs Med.Chem.Lett., 5, 2014
4BKS
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BU of 4bks by Molmil
von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-1-ethanoyl-N-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide
分子名称: (2S,4R)-1-ethanoyl-N-[[4-(1,3-oxazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ...
著者Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A.
登録日2013-04-29
公開日2013-11-27
最終更新日2014-01-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions?
Acs Med.Chem.Lett., 5, 2014
4K95
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BU of 4k95 by Molmil
Crystal Structure of Parkin
分子名称: E3 ubiquitin-protein ligase parkin, ZINC ION
著者Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K.
登録日2013-04-19
公開日2013-05-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (6.499 Å)
主引用文献Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
4K7U
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BU of 4k7u by Molmil
Crystal structure of Zn2.3-hUb (human ubiquitin) adduct from a solution 70 mM zinc acetate/1.3 mM hUb
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G.
登録日2013-04-17
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Conformational selection of ubiquitin quaternary structures driven by zinc ions.
Chemistry, 19, 2013
4K7W
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BU of 4k7w by Molmil
Crystal structure of Zn3-hUb(human ubiquitin) adduct from a solution 100 mM zinc acetate/1.3 mM hUb
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ZINC ION, ...
著者Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G.
登録日2013-04-17
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Conformational selection of ubiquitin quaternary structures driven by zinc ions.
Chemistry, 19, 2013
4K7S
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BU of 4k7s by Molmil
Crystal structure of Zn2-hUb (human ubiquitin) adduct from a solution 35 mM zinc acetate/1.3 mM hUb
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ZINC ION, ...
著者Fermani, S, Falini, G, Calvaresi, M, Bottoni, A, Arnesano, F, Natile, G.
登録日2013-04-17
公開日2013-05-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Conformational selection of ubiquitin quaternary structures driven by zinc ions.
Chemistry, 19, 2013
4K1R
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BU of 4k1r by Molmil
Crystal structure of Schizosaccharomyces pombe sst2 catalytic domain and Ubiquitin
分子名称: 1,2-ETHANEDIOL, AMSH-like protease sst2, CHLORIDE ION, ...
著者Shrestha, R.K, Das, C.
登録日2013-04-05
公開日2014-04-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.632 Å)
主引用文献Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product.
Biochemistry, 53, 2014
4JQW
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BU of 4jqw by Molmil
Crystal Structure of a Complex of NOD1 CARD and Ubiquitin
分子名称: Nucleotide-binding oligomerization domain-containing protein 1, PHOSPHATE ION, Polyubiquitin-C
著者Ver Heul, A.M, Gakhar, L, Piper, R.C, Ramaswamy, S.
登録日2013-03-20
公開日2014-03-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a complex of NOD1 CARD and ubiquitin
Plos One, 9, 2014
4JIO
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BU of 4jio by Molmil
Bro1 V domain and ubiquitin
分子名称: BRO1, Ubiquitin
著者Pashkova, N, Gakhar, L, Piper, R.C.
登録日2013-03-06
公開日2013-06-19
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The yeast alix homolog bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes.
Dev.Cell, 25, 2013
4JGH
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BU of 4jgh by Molmil
Structure of the SOCS2-Elongin BC complex bound to an N-terminal fragment of Cullin5
分子名称: Cullin-5, Suppressor of cytokine signaling 2, Transcription elongation factor B polypeptide 1, ...
著者Kim, Y.K, Kwak, M.J, Ku, B, Suh, H.Y, Joo, K, Lee, J, Jung, J.U, Oh, B.H.
登録日2013-03-01
公開日2013-08-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
Acta Crystallogr.,Sect.D, 69, 2013
3ZNZ
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BU of 3znz by Molmil
Crystal structure of OTULIN OTU domain (C129A) in complex with Met1- di ubiquitin
分子名称: POLYUBIQUITIN-C, PROTEIN FAM105B, SULFATE ION
著者Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D.
登録日2013-02-18
公開日2013-06-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3ZNI
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BU of 3zni by Molmil
Structure of phosphoTyr363-Cbl-b - UbcH5B-Ub - ZAP-70 peptide complex
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL-B, ...
著者Dou, H, Buetow, L, Sibbet, G.J, Cameron, K, Huang, D.T.
登録日2013-02-14
公開日2013-07-10
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Essentiality of a Non-Ring Element in Priming Donor Ubiquitin for Catalysis by a Monomeric E3.
Nat.Struct.Mol.Biol., 20, 2013

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