2M8S

NMR Structure of the Cytoplasmic Tail of the Membrane Form of Heparin-binding EGF-like Growth Factor (proHB-EGF-CT) Complexed with the Ubiquitin Homology Domain of Bcl-2-associated Athanogene 1 from Mus musculus (mBAG-1-UBH)

Summary for 2M8S

• Entry DOI: 10.2210/pdb2m8s/pdb
• NMR Information: BMRB: 18416
• Descriptor: BAG family molecular chaperone regulator 1, Proheparin-binding EGF-like growth factor (2 entities in total)
• Functional Keywords: mbag-1, prohb-egf-ct, chaperone-membrane protein complex, chaperone/membrane protein
• Biological source: Mus musculus (mouse); More
• Cellular location: Isoform 1: Nucleus. Isoform 2: Cytoplasm: Q60739; Heparin-binding EGF-like growth factor: Secreted, extracellular space. Proheparin-binding EGF-like growth factor: Cell membrane; Single-pass type I membrane protein: Q99075
• Total number of polymer chains: 2
• Total formula weight: 13682.59

Authors

Huang, H.W.,Yu, C. (deposition date: 2013-06-03, release date: 2014-04-16)

• Primary citation: Hung, K.W.,Huang, H.W.,Cho, C.C.,Chang, S.C.,Yu, C.; Nuclear Magnetic Resonance Structure of the Cytoplasmic Tail of Heparin Binding EGF-like Growth Factor (proHB-EGF-CT) Complexed with the Ubiquitin Homology Domain of Bcl-2-Associated Athanogene 1 from Mus musculus (mBAG-1-UBH).; Biochemistry, 53:1935-1946, 2014; PubMed: 24628338; DOI: 10.1021/bi5003019

Experimental method

SOLUTION NMR