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6FES
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BU of 6fes by Molmil
Crystal structure of novel repeat protein BRIC2 fused to DARPin D12
分子名称: 1,2-ETHANEDIOL, D12_BRIC2, a synthetic protein,D12_BRIC2, ...
著者ElGamacy, M, Coles, M, Ernst, P, Zhu, H, Hartmann, M.D, Plueckthun, A, Lupas, A.
登録日2018-01-03
公開日2018-09-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture.
ACS Synth Biol, 7, 2018
6FF6
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BU of 6ff6 by Molmil
Crystal structure of novel repeat protein BRIC1
分子名称: BRIC1
著者ElGamacy, M, Coles, M, Ernst, P, Zhu, H, Hartmann, M.D, Plueckthun, A, Lupas, A.N.
登録日2018-01-03
公開日2018-09-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture.
ACS Synth Biol, 7, 2018
4MKM
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BU of 4mkm by Molmil
Repeat domains 1 & 2 of Clostridium perfringens Cpe0147
分子名称: CALCIUM ION, Putative surface anchored protein
著者Kwon, H, Squire, C.J, Young, P.G, Baker, E.N.
登録日2013-09-05
公開日2013-12-04
最終更新日2014-02-12
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Autocatalytically generated Thr-Gln ester bond cross-links stabilize the repetitive Ig-domain shaft of a bacterial cell surface adhesin.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MQV
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BU of 4mqv by Molmil
Crystal complex of Rpa32c and Smarcal1 N-terminus
分子名称: Replication protein A 32 kDa subunit, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
著者Xie, S, Qian, C.M.
登録日2013-09-16
公開日2014-07-02
最終更新日2014-12-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of RPA32 bound to the N-terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins
Febs J., 281, 2014
4WVM
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BU of 4wvm by Molmil
Stonustoxin structure
分子名称: Stonustoxin subunit alpha, Stonustoxin subunit beta
著者Ellisdon, A.M, Panjikar, S, Whisstock, J.C, McGowan, S.
登録日2014-11-06
公開日2015-12-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Stonefish toxin defines an ancient branch of the perforin-like superfamily.
Proc.Natl.Acad.Sci.USA, 112, 2015
8GK8
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BU of 8gk8 by Molmil
R21A Staphylococcus aureus pyruvate carboxylase
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ACETYL COENZYME *A, COENZYME A, ...
著者Laseke, A.J, St.Maurice, M.
登録日2023-03-17
公開日2023-08-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Allosteric Site at the Biotin Carboxylase Dimer Interface Mediates Activation and Inhibition in Staphylococcus aureus Pyruvate Carboxylase.
Biochemistry, 62, 2023
3EWI
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BU of 3ewi by Molmil
Structural analysis of the C-terminal domain of murine CMP-Sialic acid Synthetase
分子名称: N-acylneuraminate cytidylyltransferase
著者Oschlies, M, Dickmanns, A, Stummeyer, K, Gerardy-Schahn, R, Ficner, R, Muenster-Kuehnel, A.K.
登録日2008-10-15
公開日2009-08-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A C-terminal phosphatase module conserved in vertebrate CMP-sialic acid synthetases provides a tetramerization interface for the physiologically active enzyme.
J.Mol.Biol., 393, 2009
1YG2
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BU of 1yg2 by Molmil
Structure of the Vibrio cholerae virulence activator AphA
分子名称: gene activator AphA
著者De Silva, R.S, Kovacikova, G, Lin, W, Taylor, R.T, Skorupski, K, Kull, F.J.
登録日2005-01-04
公開日2005-01-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the virulence gene activator AphA from Vibrio cholerae reveals it is a novel member of the winged helix transcription factor superfamily
J.Biol.Chem., 280, 2005
2MW7
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BU of 2mw7 by Molmil
Solution NMR structure of a novel cysteine framework containing Conus peptide Mo3964
分子名称: Mo3964
著者Sarma, S.P, Kancherla, A.
登録日2014-10-29
公開日2015-09-23
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Disulfide Stabilized beta-Sandwich Defines the Structure of a New Cysteine Framework M-Superfamily Conotoxin
Acs Chem.Biol., 10, 2015
2M89
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BU of 2m89 by Molmil
Solution structure of the Aha1 dimer from Colwellia psychrerythraea
分子名称: Aha1 domain protein
著者Rossi, P, Sgourakis, N.G, Shi, L, Liu, G, Barbieri, C.M, Lee, H, Grant, T.D, Luft, J.R, Xiao, R, Acton, T.B, Montelione, G.T, Snell, E.H, Baker, D, Lange, O.A, Northeast Structural Genomics Consortium (NESG)
登録日2013-05-09
公開日2013-09-04
最終更新日2024-05-01
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta.
Proteins, 83, 2015
1BO1
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BU of 1bo1 by Molmil
PHOSPHATIDYLINOSITOL PHOSPHATE KINASE TYPE II BETA
分子名称: PROTEIN (PHOSPHATIDYLINOSITOL PHOSPHATE KINASE IIBETA)
著者Rao, V.D, Misra, S, Boronenkov, I.V, Anderson, R.A, Hurley, J.H.
登録日1998-08-02
公開日1998-10-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation.
Cell(Cambridge,Mass.), 94, 1998
8C6Z
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BU of 8c6z by Molmil
necrotic enteritis associated Clostridium p. chitinase F8UNI4 in complex with inhibitor bisdionin C
分子名称: 1,1'-PROPANE-1,3-DIYLBIS(3,7-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE), CADMIUM ION, COBALT (II) ION, ...
著者Bloch, Y, Savvides, S.N.
登録日2023-01-12
公開日2023-05-31
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Contribution and structural characterization of Chitinases to Clostridium perfringens Pathogenesis in Broilers
To Be Published
5C6M
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BU of 5c6m by Molmil
Crystal structure of deoxyribose-phosphate aldolase from Shewanella halifaxensis
分子名称: CHLORIDE ION, Deoxyribose-phosphate aldolase, SODIUM ION
著者Weiergraeber, O.H, Dick, M, Bramski, J, Pietruszka, J.
登録日2015-06-23
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Trading off stability against activity in extremophilic aldolases.
Sci Rep, 6, 2016
5XLV
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BU of 5xlv by Molmil
Mycobacterium tuberculosis Pantothenate kinase mutant F254A
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Pantothenate kinase, ...
著者Paul, A, Kumar, P, Surolia, A, Vijayan, M.
登録日2017-05-11
公開日2018-05-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biochemical and structural studies of mutants indicate concerted movement of the dimer interface and ligand-binding region of Mycobacterium tuberculosis pantothenate kinase
Acta Crystallogr F Struct Biol Commun, 73, 2017
1H2F
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BU of 1h2f by Molmil
BACILLUS STEAROTHERMOPHILUS PHOE (previously known as yhfr) in complex with trivanadate
分子名称: PHOSPHATASE, PHOSPHATE ION, TRIVANADATE
著者Rigden, D.J, Littlejohn, J.E, Jedrzejas, M.J.
登録日2002-08-08
公開日2002-08-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Phosphate and Trivanadate Complexes of Bacillus Stearothermophilus Phosphatase Phoe: Structural and Functional Analysis in the Cofactor-Dependent Phosphoglycerate Mutase Superfamily
J.Mol.Biol., 325, 2003
5C5Y
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BU of 5c5y by Molmil
Crystal structure of deoxyribose-phosphate aldolase from Colwellia psychrerythraea (hexagonal form)
分子名称: Deoxyribose-phosphate aldolase, GLYCEROL, UNKNOWN LIGAND
著者Weiergraeber, O.H, Dick, M, Pietruszka, J.
登録日2015-06-22
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Trading off stability against activity in extremophilic aldolases.
Sci Rep, 6, 2016
6P77
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BU of 6p77 by Molmil
2.5 Angstrom structure of Caci_6494 from Catenulispora Acidiphila
分子名称: Aromatic-ring-hydroxylating dioxygenase beta subunit, GLYCEROL, TETRAETHYLENE GLYCOL, ...
著者Vuksanovic, N, Silvaggi, N.R.
登録日2019-06-05
公開日2020-06-17
最終更新日2020-09-02
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structural characterization of three noncanonical NTF2-like superfamily proteins: implications for polyketide biosynthesis.
Acta Crystallogr.,Sect.F, 76, 2020
2KJD
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BU of 2kjd by Molmil
Solution structure of extended PDZ2 domain from NHERF1 (150-270)
分子名称: Sodium/hydrogen exchange regulatory cofactor NHE-RF1
著者Bhattacharya, S, Cowburn, D, Bu, Z.
登録日2009-05-27
公開日2009-12-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A dynamic intramolecular conformational switch autoregulates the scaffolding protein NHERF1
To be Published
5BQ9
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BU of 5bq9 by Molmil
Crystal structure of uncharacterized protein lpg1496 Legionella pneumophila subsp. pneumophila
分子名称: Uncharacterized protein
著者Chang, C, Morar, M, Evdokimova, E, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2015-05-28
公開日2015-06-10
最終更新日2016-01-27
実験手法X-RAY DIFFRACTION (2.2785 Å)
主引用文献Crystal structure of the Legionella pneumophila lem10 effector reveals a new member of the HD protein superfamily.
Proteins, 83, 2015
1H2E
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BU of 1h2e by Molmil
BACILLUS STEAROTHERMOPHILUS PHOE (previously known as yhfr) in complex with phosphate
分子名称: 1,2-ETHANEDIOL, PHOSPHATASE, PHOSPHATE ION
著者Rigden, D.J, Littlejohn, J.E, Jedrzejas, M.J.
登録日2002-08-08
公開日2002-08-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Structures of Phosphate and Trivanadate Complexes of Bacillus Stearothermophilus Phosphatase Phoe: Structural and Functional Analysis in the Cofactor-Dependent Phosphoglycerate Mutase Superfamily
J.Mol.Biol., 325, 2003
2KXO
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BU of 2kxo by Molmil
Solution NMR structure of the cell division regulator MinE protein from Neisseria gonorrhoeae
分子名称: Cell division topological specificity factor
著者Ghasriani, H, Goto, N.K, Ducat, T.
登録日2010-05-11
公開日2010-10-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Appropriation of the MinD protein-interaction motif by the dimeric interface of the bacterial cell division regulator MinE.
Proc.Natl.Acad.Sci.USA, 107, 2010
3CXO
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BU of 3cxo by Molmil
Crystal structure of L-rhamnonate dehydratase from Salmonella typhimurium complexed with Mg and 3-deoxy-L-rhamnonate
分子名称: (2R,4S)-2,4,7-trihydroxyheptanoic acid, 3,6-dideoxy-L-arabino-hexonic acid, MAGNESIUM ION, ...
著者Fedorov, A.A, Fedorov, E.V, Rakus, J.F, Hubbard, B.K, Gerlt, J.A, Almo, S.C.
登録日2008-04-24
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Evolution of enzymatic activities in the enolase superfamily: L-rhamnonate dehydratase.
Biochemistry, 47, 2008
1X9G
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BU of 1x9g by Molmil
PUTATIVE MAR1 RIBONUCLEASE FROM LEISHMANIA DONOVANI
分子名称: PUTATIVE MAR1
著者Caruthers, J, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日2004-08-20
公開日2004-09-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily.
Protein Sci., 14, 2005
4X0R
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BU of 4x0r by Molmil
Crystal structure of human MxB stalk domain
分子名称: Interferon-induced GTP-binding protein Mx2
著者Yu, X.-F, Xie, W.
登録日2014-11-23
公開日2014-12-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.905 Å)
主引用文献Structural insight into the assembly of human anti-HIV dynamin-like protein MxB/Mx2.
Biochem.Biophys.Res.Commun., 456, 2015
4OC7
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BU of 4oc7 by Molmil
Retinoic acid receptor alpha in complex with (E)-3-(3'-allyl-6-hydroxy-[1,1'-biphenyl]-3-yl)acrylic acid and a fragment of the coactivator TIF2
分子名称: (2E)-3-[6-hydroxy-3'-(prop-2-en-1-yl)biphenyl-3-yl]prop-2-enoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
著者Leysen, S, Scheepstra, M, Brunsveld, L, Milroy, L.G, Ottmann, C.
登録日2014-01-08
公開日2014-10-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A natural-product switch for a dynamic protein interface.
Angew.Chem.Int.Ed.Engl., 53, 2014

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