6FES
Crystal structure of novel repeat protein BRIC2 fused to DARPin D12
Summary for 6FES
| Entry DOI | 10.2210/pdb6fes/pdb |
| Descriptor | D12_BRIC2, a synthetic protein,D12_BRIC2, a synthetic protein, SULFATE ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
| Functional Keywords | novel fold, computational design, corrugated repeat, de novo protein |
| Biological source | synthetic construct More |
| Total number of polymer chains | 4 |
| Total formula weight | 165545.37 |
| Authors | ElGamacy, M.,Coles, M.,Ernst, P.,Zhu, H.,Hartmann, M.D.,Plueckthun, A.,Lupas, A. (deposition date: 2018-01-03, release date: 2018-09-05, Last modification date: 2024-01-17) |
| Primary citation | ElGamacy, M.,Coles, M.,Ernst, P.,Zhu, H.,Hartmann, M.D.,Pluckthun, A.,Lupas, A.N. An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture. ACS Synth Biol, 7:2226-2235, 2018 Cited by PubMed: 30148951DOI: 10.1021/acssynbio.8b00224 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
Download full validation report
