PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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2PFV	S. cerevisiae Exo70 with additional residues to 2.1 Angrstrom resolution 分子名称: Exocyst complex component EXO70 著者 Moore, B.A, Robinson, H.H, Xu, Z. 登録日 2007-04-05 公開日 2007-05-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of mouse Exo70 reveals unique features of the mammalian exocyst. J.Mol.Biol., 371, 2007
4JDS	SETD7 in complex with inhibitor PF-5426 and S-adenosyl-methionine 分子名称: Histone-lysine N-methyltransferase SETD7, N-[(2R)-3-(3-cyanophenyl)-1-oxo-1-(pyrrolidin-1-yl)propan-2-yl]-8-fluoro-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide, S-ADENOSYLMETHIONINE, ... 著者 Dong, A, Wu, H, Zeng, H, Park, H, El Bakkouri, M, Barsyte, D, Vedadi, M, Tatlock, J, Owen, D, Bunnage, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2013-02-25 公開日 2013-03-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 SETD7 in complex with inhibitor PF-5426 and S-adenosyl-methionine to be published
4JEA	Crystal structure of an engineered Zn-RIDC1 construct with four interfacial disulfide bonds 分子名称: PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ZINC ION, ... 著者 Tezcan, F.A, Medina-Morales, A.M, Perez, A, Brodin, J.D. 登録日 2013-02-26 公開日 2013-08-21 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 In Vitro and Cellular Self-Assembly of a Zn-Binding Protein Cryptand via Templated Disulfide Bonds. J.Am.Chem.Soc., 135, 2013
3EJS	Golgi alpha-Mannosidase II in complex with 5-substituted swainsonine analog: (5S)-5-[2'-(4-tert-butylphenyl)ethyl]-swainsonine 分子名称: (1S,2R,5S,8R,8aR)-5-[2-(4-tert-butylphenyl)ethyl]octahydroindolizine-1,2,8-triol, (4R)-2-METHYLPENTANE-2,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kuntz, D.A, Shea, K, Rose, D.R. 登録日 2008-09-18 公開日 2009-10-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural Investigation of the Binding of 5-Substituted Swainsonine Analogues to Golgi alpha-Mannosidase II. Chembiochem, 11, 2010
4JFL	Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with 6-({(1S,5R)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-2-oxo-3,9-diazabicyclo[3.3.1]non-9-yl}sulfonyl)-1,3-benzothiazol-2(3H)-one 分子名称: 6-({(1S,5R)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-2-oxo-3,9-diazabicyclo[3.3.1]non-9-yl}sulfonyl)-1,3-benzothiazol-2(3H)-one, Peptidyl-prolyl cis-trans isomerase FKBP5 著者 Wang, Y, Kirschner, A, Fabian, A, Gopalakrishnan, R, Kress, C, Hoogeland, B, Koch, U, Kozany, C, Bracher, A, Hausch, F. 登録日 2013-02-28 公開日 2013-08-28 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control. J.Med.Chem., 56, 2013
3PV5	Structure of Legionella fallonii DegQ (N189G/P190G variant) 分子名称: DegQ 著者 Wrase, R, Scott, H, Hilgenfeld, R, Hansen, G. 登録日 2010-12-06 公開日 2011-06-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Legionella HtrA homologue DegQ is a self-compartmentizing protease that forms large 12-meric assemblies. Proc.Natl.Acad.Sci.USA, 108, 2011
3E8V	Crystal structure of a possible transglutaminase-family protein proteolytic fragment from Bacteroides fragilis 分子名称: Possible transglutaminase-family protein, UNKNOWN LIGAND 著者 Bonanno, J.B, Rutter, M, Bain, K.T, Hu, S, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2008-08-20 公開日 2008-09-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of a possible transglutaminase-family protein proteolytic fragment from Bacteroides fragilis To be Published
3PVW	Bovine GRK2 in complex with Gbetagamma subunits and a selective kinase inhibitor (CMPD103A) 分子名称: Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... 著者 Thal, D.M, Tesmer, J.J. 登録日 2010-12-07 公開日 2011-06-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Molecular Mechanism of Selectivity among G Protein-Coupled Receptor Kinase 2 Inhibitors. Mol.Pharmacol., 80, 2011
4JGS	Crystal structure of the xmrv tm retroviral fusion core 分子名称: CHLORIDE ION, MLV-related proviral Env polyprotein 著者 Cook, J.D, Aydin, H, Lee, J.E. 登録日 2013-03-02 公開日 2013-10-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of Beta- and gammaretrovirus fusion proteins reveal a role for electrostatic stapling in viral entry. J.Virol., 88, 2014
3E93	Crystal Structure of P38 Kinase in Complex with A Biaryl Amide Inhibitor 分子名称: 4-methyl-N-(3-morpholin-4-ylphenyl)-3-(3-piperidin-4-yl-1,2-benzisoxazol-6-yl)benzamide, GLYCEROL, Mitogen-activated protein kinase 14 著者 Somers, D.O, Patel, S. 登録日 2008-08-21 公開日 2008-09-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Kinase array design, back to front: Biaryl amides Bioorg.Med.Chem.Lett., 18, 2008
2PQU	Crystal structure of KH1 domain of human PCBP2 complexed to single-stranded 12-mer telomeric dna 分子名称: 12-mer C-rich strand of human telomeric DNA, Poly(rC)-binding protein 2 著者 James, T.L, Lee, J. 登録日 2007-05-02 公開日 2007-06-12 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 X-ray crystallographic and NMR studies of protein-protein and protein-nucleic acid interactions involving the KH domains from human poly(C)-binding protein-2. Rna, 13, 2007
3PNM	Crystal Structure of E.coli Dha kinase DhaK (H56A) 分子名称: PTS-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit dhaK 著者 Shi, R, McDonald, L, Matte, A, Cygler, M, Ekiel, I, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2010-11-19 公開日 2011-01-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and mechanistic insight into covalent substrate binding by Escherichia coli dihydroxyacetone kinase. Proc.Natl.Acad.Sci.USA, 108, 2011
3PX4	Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddCTP-dA Mismatch (wobble) in Ajar Conformation 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*AP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ... 著者 Wang, W, Beese, L.S. 登録日 2010-12-09 公開日 2011-10-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.582 Å) 主引用文献 Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis. Proc.Natl.Acad.Sci.USA, 108, 2011
3E46	Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington interacting protein 2) M172A mutant 分子名称: CALCIUM ION, Ubiquitin-conjugating enzyme E2-25 kDa 著者 Hughes, R.C, Wilson, R.C, Flatt, J.W, Meehan, E.J, Ng, J.D, Twigg, P.D. 登録日 2008-08-09 公開日 2008-08-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2). Acta Crystallogr.,Sect.F, 65, 2009
2ES4	Crystal structure of the Burkholderia glumae lipase-specific foldase in complex with its cognate lipase 分子名称: CALCIUM ION, IODIDE ION, Lipase, ... 著者 Pauwels, K, Wyns, L, Tommassen, J, Savvides, S.N, Van Gelder, P. 登録日 2005-10-25 公開日 2006-03-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure of a membrane-based steric chaperone in complex with its lipase substrate. Nat.Struct.Mol.Biol., 13, 2006
2GXB	Crystal Structure of The Za Domain bound to Z-RNA 分子名称: 5'-R(P*(DU)P*CP*GP*CP*GP*CP*G)-3', Double-stranded RNA-specific adenosine deaminase, SODIUM ION 著者 Athanasiadis, A, Placido, D, Rich, A. 登録日 2006-05-08 公開日 2007-05-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A Left-Handed RNA Double Helix Bound by the Zalpha Domain of the RNA-Editing Enzyme ADAR1. Structure, 15, 2007
4M11	Crystal Structure of Murine Cyclooxygenase-2 Complex with Meloxicam 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide, ... 著者 Xu, S, Banerjee, S, Hermanson, D.J, Marnett, L.J. 登録日 2013-08-02 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Oxicams Bind in a Novel Mode to the Cyclooxygenase Active Site via a Two-water-mediated H-bonding Network. J.Biol.Chem., 289, 2014
2GYY	Structure of aspartate semialdehyde dehydrogenase (ASADH) from Streptococcus pneumoniae 分子名称: Aspartate beta-semialdehyde dehydrogenase 著者 Faehnle, C.R, Le Coq, J, Liu, X, Viola, R.E. 登録日 2006-05-10 公開日 2006-08-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Examination of key intermediates in the catalytic cycle of aspartate-beta-semialdehyde dehydrogenase from a gram-positive infectious bacteria. J.Biol.Chem., 281, 2006
4J5U	X-ray crystal structure of a serine hydroxymethyltransferase with covalently bound PLP from Rickettsia rickettsii str. Sheila Smith 分子名称: Serine hydroxymethyltransferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-02-10 公開日 2013-03-13 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 X-ray crystal structure of a serine hydroxymethyltransferase with covalently bound PLP from Rickettsia rickettsii str. Sheila Smith TO BE PUBLISHED
4M2U	Carbonic Anhydrase II in complex with Dorzolamide 分子名称: (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, Carbonic anhydrase 2, ZINC ION 著者 Pinard, M.P, Boone, C.D, Rife, B.D, Supuran, C.T, Mckenna, R. 登録日 2013-08-05 公開日 2013-11-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases. Bioorg.Med.Chem., 21, 2013
4JIM	Native Crystal Structure of N10-Formyltetrahydrofolate Synthetase 分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Formate--tetrahydrofolate ligase, SULFATE ION 著者 Celeste, L.R, Lovelace, L.L, Lebioda, L. 登録日 2013-03-06 公開日 2013-03-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors. Protein Sci., 21, 2012
2ESK	Human Ubiquitin-Conjugating Enzyme (E2) UbcH5b, wild-type 分子名称: Ubiquitin-conjugating enzyme E2 D2 著者 Ozkan, E, Yu, H, Deisenhofer, J. 登録日 2005-10-26 公開日 2005-12-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases Proc.Natl.Acad.Sci.Usa, 102, 2005
2PMC	Crystal Structure of CheY-Mg(2+) in Complex with CheZ(C15) Peptide solved from a P1 Crystal 分子名称: Chemotaxis protein cheY, Chemotaxis protein cheZ, MAGNESIUM ION 著者 Guhaniyogi, J, Stock, A.M. 登録日 2007-04-20 公開日 2008-01-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.688 Å) 主引用文献 Interaction of CheY with the C-terminal peptide of CheZ. J.Bacteriol., 190, 2008
4JJ6	Crystal structure of a catalytic mutant of Axe2 (Axe2-H194A), an acetylxylan esterase from Geobacillus stearothermophilus 分子名称: Acetyl xylan esterase, CHLORIDE ION, GLYCEROL 著者 Lansky, S, Alalouf, O, Solomon, V, Alhassid, A, Belrahli, H, Govada, L, Chayan, N.E, Shoham, Y, Shoham, G. 登録日 2013-03-07 公開日 2014-03-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 To be published To be published
3EBU	Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability 分子名称: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase 著者 Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H. 登録日 2008-08-28 公開日 2010-03-02 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability . Biochemistry, 49, 2010

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