3PX4

Crystal Structure of Bacillus DNA Polymerase I Large Fragment Bound to DNA and ddCTP-dA Mismatch (wobble) in Ajar Conformation

Summary for 3PX4

• Entry DOI: 10.2210/pdb3px4/pdb
• Related: 3PV8 3PX0 3PX6
• Descriptor: DNA polymerase I, DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), DNA (5'-D(*CP*AP*TP*AP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ... (7 entities in total)
• Functional Keywords: dna polymerase i, protein-dna complex, transferase-dna complex, cytosine-adenine, closed conformation, transferase/dna
• Biological source: Geobacillus kaustophilus
• Total number of polymer chains: 6
• Total formula weight: 149452.12

Authors

Wang, W.,Beese, L.S. (deposition date: 2010-12-09, release date: 2011-10-19, Last modification date: 2023-09-13)

• Primary citation: Wang, W.,Hellinga, H.W.,Beese, L.S.; Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis.; Proc.Natl.Acad.Sci.USA, 108:17644-17648, 2011; PubMed: 22006298; DOI: 10.1073/pnas.1114496108

Experimental method

X-RAY DIFFRACTION (1.582 Å)