1AZD
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![BU of 1azd by Molmil](/molmil-images/mine/1azd) | CONCANAVALIN FROM CANAVALIA BRASILIENSIS | 分子名称: | CALCIUM ION, CONBR, MANGANESE (II) ION | 著者 | Sanz-Aparicio, J, Hermoso, J, Grangeiro, T.B, Calvete, J.J, Cavada, B.S. | 登録日 | 1997-11-16 | 公開日 | 1998-04-29 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The crystal structure of Canavalia brasiliensis lectin suggests a correlation between its quaternary conformation and its distinct biological properties from Concanavalin A. FEBS Lett., 405, 1997
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6MAM
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![BU of 6mam by Molmil](/molmil-images/mine/6mam) | Cleaved Ebola GP in complex with a broadly neutralizing human antibody, ADI-15946 | 分子名称: | ADI-15946 Fab Heavy Chain, ADI-15946 Fab Light Chain, Envelope glycoprotein, ... | 著者 | West, B.R, Moyer, C.L, Fusco, M.L, Saphire, E.O. | 登録日 | 2018-08-28 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Structural basis of broad ebolavirus neutralization by a human survivor antibody. Nat. Struct. Mol. Biol., 26, 2019
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5KSU
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![BU of 5ksu by Molmil](/molmil-images/mine/5ksu) | Crystal structure of HLA-DQ2.5-CLIP1 at 2.73 resolution | 分子名称: | HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DQ alpha 1 chain, ... | 著者 | Nguyen, T.-B, Jayaraman, P, Bergseng, E, Madhusudhan, M.S, Kim, C.-Y, Sollid, L.M. | 登録日 | 2016-07-10 | 公開日 | 2017-04-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides. J. Biol. Chem., 292, 2017
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1AV2
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![BU of 1av2 by Molmil](/molmil-images/mine/1av2) | Gramicidin A/CsCl complex, active as a dimer | 分子名称: | CESIUM ION, CHLORIDE ION, GRAMICIDIN A, ... | 著者 | Burkhart, B.M, Li, N, Langs, D.A, Duax, W.L. | 登録日 | 1997-09-23 | 公開日 | 1998-07-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | The Conducting Form of Gramicidin a is a Right-Handed Double-Stranded Double Helix. Proc.Natl.Acad.Sci.USA, 95, 1998
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6PHF
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1ASZ
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![BU of 1asz by Molmil](/molmil-images/mine/1asz) | THE ACTIVE SITE OF YEAST ASPARTYL-TRNA SYNTHETASE: STRUCTURAL AND FUNCTIONAL ASPECTS OF THE AMINOACYLATION REACTION | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ASPARTYL-tRNA SYNTHETASE, T-RNA (75-MER) | 著者 | Cavarelli, J, Rees, B, Thierry, J.C, Moras, D. | 登録日 | 1995-01-19 | 公開日 | 1995-05-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction. EMBO J., 13, 1994
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5KUB
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8PJI
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![BU of 8pji by Molmil](/molmil-images/mine/8pji) | MLLT1 in complex with compound 10a | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Protein ENL, ... | 著者 | Raux, B, Diaz-Saez, L, Huber, K.V.M, Fedorov, O, Owen, D.R, Londregan, A.T, Bountra, C, Edwards, A, Arrowsmith, C. | 登録日 | 2023-06-23 | 公開日 | 2023-11-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3. Bioorg.Med.Chem.Lett., 98, 2023
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6MAK
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![BU of 6mak by Molmil](/molmil-images/mine/6mak) | HBO1 is required for the maintenance of leukaemia stem cells | 分子名称: | ACETYL COENZYME *A, BRD1 protein, Histone acetyltransferase KAT7, ... | 著者 | Ren, B, Peat, T.S, Monahan, B, Dawson, M, Street, I. | 登録日 | 2018-08-27 | 公開日 | 2019-12-25 | 最終更新日 | 2020-01-22 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | HBO1 is required for the maintenance of leukaemia stem cells. Nature, 577, 2020
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8PJ7
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![BU of 8pj7 by Molmil](/molmil-images/mine/8pj7) | MLLT3 in complex with compound PFI-6 | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... | 著者 | Raux, B, Diaz-Saez, L, Huber, K.V.M, Fedorov, O, Owen, D.R, Londregan, A.T, Bountra, C, Edwards, A, Arrowsmith, C. | 登録日 | 2023-06-22 | 公開日 | 2023-11-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Discovery of PFI-6, a small-molecule chemical probe for the YEATS domain of MLLT1 and MLLT3. Bioorg.Med.Chem.Lett., 98, 2023
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6P01
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8SDH
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7SQ5
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![BU of 7sq5 by Molmil](/molmil-images/mine/7sq5) | Designed trefoil knot protein, variant 3 | 分子名称: | Designed trefoil knot protein, variant 3, SODIUM ION | 著者 | Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. | 登録日 | 2021-11-04 | 公開日 | 2022-11-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | 主引用文献 | De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
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7SRK
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6VGI
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![BU of 6vgi by Molmil](/molmil-images/mine/6vgi) | Crystal Structures of FLAP bound to MK-866 | 分子名称: | 3-[3-(tert-butylsulfanyl)-1-[(4-chlorophenyl)methyl]-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid, 5-lipoxygenase-activating protein, SULFATE ION | 著者 | Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H. | 登録日 | 2020-01-08 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP). Biochim Biophys Acta Gen Subj, 1865, 2020
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6EXO
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![BU of 6exo by Molmil](/molmil-images/mine/6exo) | Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor | 分子名称: | (3~{S},14~{E})-19-chloranyl-~{N}-(1-cyanocyclopropyl)-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(21),6(11),7,9,14,18(22),19-heptaene-3-carboxamide, 1,2-ETHANEDIOL, Cysteine protease | 著者 | Dietzel, U, Kisker, C. | 登録日 | 2017-11-08 | 公開日 | 2018-04-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors. J. Med. Chem., 61, 2018
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8Q7I
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4WY7
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![BU of 4wy7 by Molmil](/molmil-images/mine/4wy7) | Crystal structure of recombinant 4E10 expressed in Escherichia coli with epitope bound | 分子名称: | Envelope glycoprotein gp160, Fab 4E10 Heavy chain, Fab 4E10Light chain, ... | 著者 | Rujas, E, Morante, K, Tsumoto, K, Nieva, J.L, Caaveiro, J.M.M. | 登録日 | 2014-11-16 | 公開日 | 2015-03-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region. J.Biol.Chem., 290, 2015
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1C04
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![BU of 1c04 by Molmil](/molmil-images/mine/1c04) | IDENTIFICATION OF KNOWN PROTEIN AND RNA STRUCTURES IN A 5 A MAP OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI | 分子名称: | 23S RRNA FRAGMENT, RIBOSOMAL PROTEIN L11, RIBOSOMAL PROTEIN L14, ... | 著者 | Ban, N, Nissen, P, Capel, M, Moore, P.B, Steitz, T.A. | 登録日 | 1999-07-14 | 公開日 | 1999-08-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (5 Å) | 主引用文献 | Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit. Nature, 400, 1999
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7ZM6
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![BU of 7zm6 by Molmil](/molmil-images/mine/7zm6) | Nariva virus receptor binding protein | 分子名称: | Attachment protein | 著者 | Stelfox, A.J, Rissanen, I, Rambo, R, Lee, B, Bowden, T.A. | 登録日 | 2022-04-19 | 公開日 | 2023-09-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystal structure and solution state of the C-terminal head region of the narmovirus receptor binding protein. Mbio, 14, 2023
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4XAE
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![BU of 4xae by Molmil](/molmil-images/mine/4xae) | Structure of Feruloyl-CoA 6-hydroxylase (F6H) from Arabidopsis thaliana | 分子名称: | Feruloyl CoA ortho-hydroxylase 1, SODIUM ION | 著者 | Zhou, D, Kandavelu, P, Zhang, H, Wang, B.C, Rose, J, Yan, Y. | 登録日 | 2014-12-14 | 公開日 | 2015-06-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.769 Å) | 主引用文献 | Structural Insights into Substrate Specificity of Feruloyl-CoA 6'-Hydroxylase from Arabidopsis thaliana. Sci Rep, 5, 2015
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7T1E
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![BU of 7t1e by Molmil](/molmil-images/mine/7t1e) | Structure of monomeric and dimeric human CCL20 | 分子名称: | C-C motif chemokine 20, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Peterson, F.C, Riutta, S.J, Volkman, B.F. | 登録日 | 2021-12-01 | 公開日 | 2022-12-14 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.459 Å) | 主引用文献 | The Chemokine, CCL20, and Its Receptor, CCR6, in the Pathogenesis and Treatment of Psoriasis and Psoriatic Arthritis J Psoriasis Psoriatic Arthritis, 8, 2023
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8THM
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8D0Q
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![BU of 8d0q by Molmil](/molmil-images/mine/8d0q) | Human FUT9 bound to GDP-CF3-Fucose and H-Type 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Kadirvelraj, R, Wood, Z.A. | 登録日 | 2022-05-26 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9. Nat.Chem.Biol., 19, 2023
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6SMQ
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![BU of 6smq by Molmil](/molmil-images/mine/6smq) | Structure of the RagAB peptide importer in the 'open-closed' state | 分子名称: | (1R,4S,6R)-6-({[2-(ACETYLAMINO)-2-DEOXY-ALPHA-D-GLUCOPYRANOSYL]OXY}METHYL)-4-HYDROXY-1-{[(15-METHYLHEXADECANOYL)OXY]METHYL}-4-OXIDO-7-OXO-3,5-DIOXA-8-AZA-4-PHOSPHAHEPTACOS-1-YL 15-METHYLHEXADECANOATE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Lipoprotein RagB, ... | 著者 | White, J.B.R, Ranson, N.A, van den Berg, B. | 登録日 | 2019-08-22 | 公開日 | 2020-05-20 | 最終更新日 | 2020-08-05 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural and functional insights into oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis. Nat Microbiol, 5, 2020
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