PDB: 2035 件ウェブページステータス検索Chemie searchBIRD

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5K9C	Crystal structure of human dihydroorotate dehydrogenase with ML390 分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, ACETATE ION, CHLORIDE ION, ... 著者 Lewis, T.A, Sykes, D.B, Law, J.M, Munoz, B, Scadden, D.T, Rustiguel, J.K, Nonato, M.C, Schreiber, S.L. 登録日 2016-05-31 公開日 2016-10-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Med Chem Lett, 7, 2016
5K4Z	M. thermoresistible IMPDH in complex with IMP and Compound 6 分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, ~{N}-(4-fluorophenyl)-4-(2~{H}-indazol-6-ylsulfamoyl)-3,5-dimethyl-1~{H}-pyrrole-2-carboxamide 著者 Pacitto, A, Ascher, D.B, Blundell, T.L. 登録日 2016-05-22 公開日 2016-10-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis. ACS Infect Dis, 3, 2017
5K4X	M. thermoresistible IMPDH in complex with IMP and Compound 1 分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, ~{N}-(2~{H}-indazol-6-yl)-3,5-dimethyl-1~{H}-pyrazole-4-sulfonamide 著者 Pacitto, A, Ascher, D.B, Blundell, T.L. 登録日 2016-05-22 公開日 2016-10-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis. ACS Infect Dis, 3, 2017
5K0Y	m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face 分子名称: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ... 著者 Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y. 登録日 2016-05-17 公開日 2016-07-13 最終更新日 2018-04-18 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition. Mol.Cell, 63, 2016
5JZL	The Structure of Monomeric Ultra Stable Green Fluorescent Protein 分子名称: CHLORIDE ION, Green fluorescent protein, SODIUM ION 著者 Gunn, N.J, Yong, K.J, Scott, D.J, Griffin, M.D.W. 登録日 2016-05-17 公開日 2017-12-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Novel Ultra-Stable, Monomeric Green Fluorescent Protein For Direct Volumetric Imaging of Whole Organs Using CLARITY. Sci Rep, 8, 2018
5JZK	The Structure of Ultra Stable Green Fluorescent Protein 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... 著者 Yong, K.J, Gunn, N.J, Scott, D.J, Griffin, M.D.W. 登録日 2016-05-17 公開日 2017-12-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Novel Ultra-Stable, Monomeric Green Fluorescent Protein For Direct Volumetric Imaging of Whole Organs Using CLARITY. Sci Rep, 8, 2018
5JUU	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. 登録日 2016-05-10 公開日 2016-10-05 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
5JUT	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure IV (almost non-rotated 40S subunit) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. 登録日 2016-05-10 公開日 2016-10-05 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
5JUS	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure III (mid-rotated 40S subunit) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. 登録日 2016-05-10 公開日 2016-10-05 最終更新日 2023-04-05 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
5JUP	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure II (mid-rotated 40S subunit) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. 登録日 2016-05-10 公開日 2016-10-05 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
5JUO	Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure I (fully rotated 40S subunit) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. 登録日 2016-05-10 公開日 2016-10-05 最終更新日 2019-11-27 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
5JPQ	Cryo-EM structure of the 90S pre-ribosome 分子名称: 18S ribosomal RNA, Bms1, Emg1, ... 著者 Turk, M, Cheng, J, Berninghausen, O, Kornprobst, M, Flemming, D, Kos-Braun, I.C, Kos, M, Thoms, M, Hurt, E, Beckmann, R. 登録日 2016-05-04 公開日 2016-07-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.3 Å) 主引用文献 Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome. Cell, 166, 2016
5JG4	Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila 分子名称: CITRATE ANION, GLYCEROL, PHOSPHATE ION, ... 著者 Beyrakhova, K, van Straaten, K, Cygler, M. 登録日 2016-04-19 公開日 2016-05-04 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila. J.Biol.Chem., 291, 2016
5JBH	Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-IN conformation 分子名称: 16S ribosomal RNA, 30S ribosomal protein SX, 30S ribosomal protein eL41, ... 著者 Coureux, P.-D, Schmitt, E, Mechulam, Y. 登録日 2016-04-13 公開日 2016-12-07 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (5.34 Å) 主引用文献 Cryo-EM study of start codon selection during archaeal translation initiation. Nat Commun, 7, 2016
5JB3	Cryo-EM structure of a full archaeal ribosomal translation initiation complex in the P-REMOTE conformation 分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Coureux, P.-D, Schmitt, E, Mechulam, Y. 登録日 2016-04-13 公開日 2016-11-30 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (5.34 Å) 主引用文献 Cryo-EM study of start codon selection during archaeal translation initiation. Nat Commun, 7, 2016
5J3N	C-terminal domain of EcoR124I HsdR subunit fused with the pH-sensitive GFP variant ratiometric pHluorin 分子名称: Green fluorescent protein,HsdR 著者 Grinkevich, P, Iermak, I, Luedtke, N, Mesters, J.R, Ettrich, R, Ludwig, J. 登録日 2016-03-31 公開日 2017-04-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of a novel domain of the motor subunit of the Type I restriction enzyme EcoR124 involved in complex assembly and DNA binding. J. Biol. Chem., 293, 2018
5J2O	Crystal structure of the cyan fluorescence protein Cerulean S175G mutant 分子名称: Green fluorescent protein 著者 Park, S.-W, Kang, S, Yoon, T.-S. 登録日 2016-03-29 公開日 2016-04-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of the cyan fluorescent protein Cerulean-S175G Acta Crystallogr.,Sect.F, 72, 2016
5IT9	Structure of the yeast Kluyveromyces lactis small ribosomal subunit in complex with the cricket paralysis virus IRES. 分子名称: 18S ribosomal RNA, Cricket paralysis virus IRES RNA, MAGNESIUM ION, ... 著者 Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S. 登録日 2016-03-16 公開日 2016-05-18 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural characterization of ribosome recruitment and translocation by type IV IRES. Elife, 5, 2016
5IT7	Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2 分子名称: (2S)-1-amino-N,N,N-trimethyl-1-oxobutan-2-aminium, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S. 登録日 2016-03-16 公開日 2016-05-18 最終更新日 2018-11-21 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural characterization of ribosome recruitment and translocation by type IV IRES. Elife, 5, 2016
5IH6	Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A derivative 分子名称: 6-(3-bromophenyl)pteridine-2,4,7-triamine, Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, ... 著者 Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H. 登録日 2016-02-29 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol, 23, 2016
5IH5	Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A 分子名称: 6-(3-chlorophenyl)pteridine-2,4,7-triamine, Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, ... 著者 Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H. 登録日 2016-02-29 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol, 23, 2016
5IH4	Human Casein Kinase 1 isoform delta apo (kinase domain) 分子名称: Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, SULFATE ION, ... 著者 Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H. 登録日 2016-02-29 公開日 2016-04-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol, 23, 2016
5IDF	Cryo-EM structure of GluA2/3 AMPA receptor heterotetramer (model II) 分子名称: Glutamate receptor 2, Glutamate receptor 3 著者 Herguedas, B, Garcia-Nafria, J, Fernandez-Leiro, R, Greger, I.H. 登録日 2016-02-24 公開日 2016-03-16 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (10.31 Å) 主引用文献 Structure and organization of heteromeric AMPA-type glutamate receptors. Science, 352, 2016
5IDE	Cryo-EM structure of GluA2/3 AMPA receptor heterotetramer (model I) 分子名称: Glutamate receptor 2, Glutamate receptor 3 著者 Herguedas, B, Garcia-Nafria, J, Fernandez-Leiro, R, Greger, I.H. 登録日 2016-02-24 公開日 2016-03-16 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (8.25 Å) 主引用文献 Structure and organization of heteromeric AMPA-type glutamate receptors. Science, 352, 2016
5I4L	Crystal structure of Amicoumacin A bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Prokhorova, I.V, Yusupova, G, Yusupov, M. 登録日 2016-02-12 公開日 2016-06-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome. Sci Rep, 6, 2016

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