1NUJ
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![BU of 1nuj by Molmil](/molmil-images/mine/1nuj) | THE LEADZYME STRUCTURE BOUND TO MG(H20)6(II) AT 1.8 A RESOLUTION | 分子名称: | 5'-R(*CP*GP*GP*AP*CP*CP*GP*AP*GP*CP*CP*AP*G)-3', 5'-R(*GP*CP*UP*GP*GP*GP*AP*GP*UP*CP*C)-3', MAGNESIUM ION | 著者 | Wedekind, J.E, Mckay, D.B. | 登録日 | 2003-01-31 | 公開日 | 2003-08-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the leadzyme at 1.8 A resolution: metal ion binding and the implications
for catalytic mechanism and allo site ion regulation. BIOCHEMISTRY, 42, 2003
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1NW9
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![BU of 1nw9 by Molmil](/molmil-images/mine/1nw9) | STRUCTURE OF CASPASE-9 IN AN INHIBITORY COMPLEX WITH XIAP-BIR3 | 分子名称: | Baculoviral IAP repeat-containing protein 4, ZINC ION, caspase 9, ... | 著者 | Shiozaki, E.N, Chai, J, Rigotti, D.J, Riedl, S.J, Li, P, Srinivasula, S.M, Alnemri, E.S, Fairman, R, Shi, Y. | 登録日 | 2003-02-05 | 公開日 | 2003-03-25 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mechanism of XIAP-Mediated Inhibition of Caspase-9 Mol.Cell, 11, 2003
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6UJB
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![BU of 6ujb by Molmil](/molmil-images/mine/6ujb) | Integrin alpha-v beta-8 in complex with the Fabs C6D4 and 11D12v2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C6D4 heavy chain Fab, ... | 著者 | Campbell, M.G, Cormier, A, Cheng, Y, Nishimura, S.L. | 登録日 | 2019-10-02 | 公開日 | 2020-02-05 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | 主引用文献 | Cryo-EM Reveals Integrin-Mediated TGF-beta Activation without Release from Latent TGF-beta. Cell, 180, 2020
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6UJS
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1BCB
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![BU of 1bcb by Molmil](/molmil-images/mine/1bcb) | INTRAMOLECULAR TRIPLEX, NMR, 10 STRUCTURES | 分子名称: | DNA (5'-D(*AP*GP*AP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*TP*CP*T)-3') | 著者 | Asensio, J.L, Brown, T, Lane, A.N. | 登録日 | 1998-04-29 | 公開日 | 1998-08-12 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Comparison of the solution structures of intramolecular DNA triple helices containing adjacent and non-adjacent CG.C+ triplets. Nucleic Acids Res., 26, 1998
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6UJN
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![BU of 6ujn by Molmil](/molmil-images/mine/6ujn) | P-glycoprotein mutant-C952A-with BDE100 | 分子名称: | 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1 | 著者 | Aller, S.G, Le, C.A. | 登録日 | 2019-10-03 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.98 Å) | 主引用文献 | Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj, 7, 2020
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2K9E
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![BU of 2k9e by Molmil](/molmil-images/mine/2k9e) | |
1FV1
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![BU of 1fv1 by Molmil](/molmil-images/mine/1fv1) | STRUCTURAL BASIS FOR THE BINDING OF AN IMMUNODOMINANT PEPTIDE FROM MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES | 分子名称: | GLYCEROL, MAJOR HISTOCOMPATIBILITY COMPLEX ALPHA CHAIN, MAJOR HISTOCOMPATIBILITY COMPLEX BETA CHAIN, ... | 著者 | Li, H, Mariuzza, A.R, Li, Y, Martin, R. | 登録日 | 2000-09-18 | 公開日 | 2000-09-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins. J.Mol.Biol., 304, 2000
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2K6D
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1HUI
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![BU of 1hui by Molmil](/molmil-images/mine/1hui) | INSULIN MUTANT (B1, B10, B16, B27)GLU, DES-B30, NMR, 25 STRUCTURES | 分子名称: | INSULIN | 著者 | Olsen, H.B, Ludvigsen, S, Kaarsholm, N.C. | 登録日 | 1996-03-29 | 公開日 | 1997-03-12 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of an engineered insulin monomer at neutral pH. Biochemistry, 35, 1996
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2KA9
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![BU of 2ka9 by Molmil](/molmil-images/mine/2ka9) | Solution structure of PSD-95 PDZ12 complexed with cypin peptide | 分子名称: | Disks large homolog 4, cypin peptide | 著者 | Wang, W.N, Weng, J.W, Zhang, X, Liu, M.L, Zhang, M.J. | 登録日 | 2008-11-03 | 公開日 | 2009-06-23 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Creating conformational entropy by increasing interdomain mobility in ligand binding regulation: a revisit to N-terminal tandem PDZ domains of PSD-95 J.Am.Chem.Soc., 131, 2009
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6VBH
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![BU of 6vbh by Molmil](/molmil-images/mine/6vbh) | Human XPG endonuclease catalytic domain | 分子名称: | DNA repair protein complementing XP-G cells,Flap endonuclease 1, SULFATE ION | 著者 | Tsutakawa, S.E, Arvai, A.S, Tainer, J.A. | 登録日 | 2019-12-18 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.995 Å) | 主引用文献 | Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations. Proc.Natl.Acad.Sci.USA, 117, 2020
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1B4O
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6USZ
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![BU of 6usz by Molmil](/molmil-images/mine/6usz) | Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Vigers, G.P, Smith, D.J. | 登録日 | 2019-10-28 | 公開日 | 2020-04-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Identification of the Clinical Development CandidateMRTX849, a Covalent KRASG12CInhibitor for the Treatment of Cancer. J.Med.Chem., 63, 2020
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1BHL
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![BU of 1bhl by Molmil](/molmil-images/mine/1bhl) | CACODYLATED CATALYTIC DOMAIN OF HIV-1 INTEGRASE | 分子名称: | HIV-1 INTEGRASE | 著者 | Maignan, S, Guilloteau, J.P, Zhou-Liu, Q, Clement-Mella, C, Mikol, V. | 登録日 | 1998-06-10 | 公開日 | 1998-10-14 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases. J.Mol.Biol., 282, 1998
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1AQQ
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![BU of 1aqq by Molmil](/molmil-images/mine/1aqq) | AG-SUBSTITUTED METALLOTHIONEIN FROM SACCHAROMYCES CEREVISIAE, NMR, 10 STRUCTURES | 分子名称: | AG-METALLOTHIONEIN, SILVER ION | 著者 | Peterson, C.W, Narula, S.S, Armitage, I.M. | 登録日 | 1997-07-31 | 公開日 | 1997-12-24 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | 3D solution structure of copper and silver-substituted yeast metallothioneins. FEBS Lett., 379, 1996
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2KTT
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![BU of 2ktt by Molmil](/molmil-images/mine/2ktt) | Solution Structure of a Covalently Bound Pyrrolo[2,1-c][1,4]benzodiazepine-Benzimidazole Hybrid to a 10mer DNA Duplex | 分子名称: | (11aS)-7-methoxy-8-(3-{4-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]phenoxy}propoxy)-1,2,3,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 5'-D(*AP*AP*CP*AP*AP*TP*TP*GP*TP*T)-3' | 著者 | Rettig, M, Weingarth, M, Langel, W, Kamal, A, Kumar, P.P, Weisz, K. | 登録日 | 2010-02-08 | 公開日 | 2010-03-09 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a covalently bound pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole hybrid to a 10mer DNA duplex. Biochemistry, 48, 2009
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6VAL
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7DTO
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![BU of 7dto by Molmil](/molmil-images/mine/7dto) | |
1BZ7
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![BU of 1bz7 by Molmil](/molmil-images/mine/1bz7) | FAB FRAGMENT FROM MURINE ASCITES | 分子名称: | PROTEIN (ANTIBODY R24 (HEAVY CHAIN)), PROTEIN (ANTIBODY R24 (LIGHT CHAIN)) | 著者 | Kaminski, M.J, Mackenzie, C.R, Mooibroek, M.J, Dahms, T.E.S, Hirama, T, Houghton, A.N, Chapman, P.B, Evans, S.V. | 登録日 | 1998-11-06 | 公開日 | 1999-11-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The role of homophilic binding in anti-tumor antibody R24 recognition of molecular surfaces. Demonstration of an intermolecular beta-sheet interaction between vh domains. J.Biol.Chem., 274, 1999
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2LQW
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1C1X
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![BU of 1c1x by Molmil](/molmil-images/mine/1c1x) | L-PHENYLALANINE DEHYDROGENASE STRUCTURE IN TERNARY COMPLEX WITH NAD+ AND L-3-PHENYLLACTATE | 分子名称: | ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, ISOPROPYL ALCOHOL, L-PHENYLALANINE DEHYDROGENASE, ... | 著者 | Vanhooke, J.L, Thoden, J.B. | 登録日 | 1999-07-22 | 公開日 | 2000-08-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Rhodococcus L-phenylalanine dehydrogenase: kinetics, mechanism, and structural basis for catalytic specificity. Biochemistry, 39, 2000
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1H0A
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![BU of 1h0a by Molmil](/molmil-images/mine/1h0a) | Epsin ENTH bound to Ins(1,4,5)P3 | 分子名称: | 1,4-DIETHYLENE DIOXIDE, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, EPSIN | 著者 | Ford, M.G.J, McMahon, H.T, Evans, P.R. | 登録日 | 2002-06-12 | 公開日 | 2002-10-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Curvature of Clathrin-Coated Pits Driven by Epsin Nature, 419, 2002
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7E3D
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![BU of 7e3d by Molmil](/molmil-images/mine/7e3d) | Crystal structure of human acetylcholinesterase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Acetylcholinesterase | 著者 | Dileep, K.V, Ihara, K, Mishima-Tsumagari, C, Kukimoto-Niino, M, Yonemochi, M, Hanada, K, Shirouzu, M, Zhang, K.Y.J. | 登録日 | 2021-02-08 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of human acetylcholinesterase in complex with tacrine: Implications for drug discovery Int.J.Biol.Macromol., 210, 2022
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1BK4
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![BU of 1bk4 by Molmil](/molmil-images/mine/1bk4) | CRYSTAL STRUCTURE OF RABBIT LIVER FRUCTOSE-1,6-BISPHOSPHATASE AT 2.3 ANGSTROM RESOLUTION | 分子名称: | MAGNESIUM ION, PROTEIN (FRUCTOSE-1,6-BISPHOSPHATASE), SULFATE ION | 著者 | Ghosh, D, Weeks, C.M, Erman, M, Roszak, A.W, Kaiser, R, Jornvall, H. | 登録日 | 1998-07-14 | 公開日 | 1998-07-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of rabbit liver fructose 1,6-bisphosphatase at 2.3 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
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