6VBH
Human XPG endonuclease catalytic domain
Summary for 6VBH
Entry DOI | 10.2210/pdb6vbh/pdb |
Descriptor | DNA repair protein complementing XP-G cells,Flap endonuclease 1, SULFATE ION (3 entities in total) |
Functional Keywords | metalloprotein, replication, dna damage, dna repair, nucloetide excision repair, xpg, xeroderma pigmentosum, 5' nuclease, hydrolase-dna complex, dna binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 41561.82 |
Authors | Tsutakawa, S.E.,Arvai, A.S.,Tainer, J.A. (deposition date: 2019-12-18, release date: 2020-06-17, Last modification date: 2023-10-11) |
Primary citation | Tsutakawa, S.E.,Sarker, A.H.,Ng, C.,Arvai, A.S.,Shin, D.S.,Shih, B.,Jiang, S.,Thwin, A.C.,Tsai, M.S.,Willcox, A.,Her, M.Z.,Trego, K.S.,Raetz, A.G.,Rosenberg, D.,Bacolla, A.,Hammel, M.,Griffith, J.D.,Cooper, P.K.,Tainer, J.A. Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations. Proc.Natl.Acad.Sci.USA, 117:14127-14138, 2020 Cited by PubMed: 32522879DOI: 10.1073/pnas.1921311117 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.995 Å) |
Structure validation
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