PDB: 226262 件ウェブページステータス検索Chemie searchBIRD

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8HIM	A cryo-EM structure of B. oleracea RNA polymerase V elongation complex at 2.73 Angstrom 分子名称: DNA (34-MER), DNA-directed RNA polymerase IV and V subunit 2, DNA-directed RNA polymerase V largest subunit, ... 著者 Hu, H, Xie, G, Du, X, Du, J. 登録日 2022-11-21 公開日 2023-03-22 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structure and mechanism of the plant RNA polymerase V. Science, 379, 2023
2RUD	Solution structure of the peptidyl prolyl cis-trans isomerase domain of C113D mutant human Pin1 with sulfate ion 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Xu, N, Tamari, Y, Tochio, N, Tate, S. 登録日 2014-03-25 公開日 2014-12-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif. Biochemistry, 53, 2014
8HB3	Crystal structure of NAD-II riboswitch (two strands) with NR 分子名称: Nicotinamide riboside, RNA (31-MER), RNA (5'-R(*AP*GP*AP*GP*CP*GP*UP*UP*GP*CP*GP*UP*CP*CP*GP*AP*AP*AP*GP*UP*(CBV)P*GP*CP*C)-3') 著者 Peng, X, Lilley, D.M.J, Huang, L. 登録日 2022-10-27 公開日 2023-03-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 Crystal structures of the NAD+-II riboswitch reveal two distinct ligand-binding pockets. Nucleic Acids Res., 51, 2023
5SPV	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with REAL250003774401 分子名称: 2-[methyl-[(9-oxidanylidene-1$l^{4},7,8-triazabicyclo[4.3.0]nona-1(6),2,4-trien-3-yl)carbonyl]amino]ethanoic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
2RRK	Solution structure of the E. coli ORF135 protein 分子名称: CTP pyrophosphohydrolase 著者 Kawasaki, K, Mishima, M. 登録日 2011-01-01 公開日 2012-01-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of the E. coli ORF135 protein To be Published
4URW	The crystal structure of H-Ras and SOS in complex with ligands 分子名称: 2-(2,6-DIMETHYLPHENYL)-4-(METHYLSULFANYL)-6-(PIPERAZIN-1-YL)-1,3,5-TRIAZINE, GTPASE HRAS, SON OF SEVENLESS HOMOLOG 1 著者 Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. 登録日 2014-07-02 公開日 2015-03-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
8HGW	Crystal structure of MehpH in complex with MBP 分子名称: 1-BUTANOL, Monoalkyl phthalate hydrolase, PHTHALIC ACID 著者 Zhang, Z.M, Wang, Y.J, Chen, Y.B. 登録日 2022-11-15 公開日 2023-03-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.80001163 Å) 主引用文献 Molecular insights into the catalytic mechanism of plasticizer degradation by a monoalkyl phthalate hydrolase. Commun Chem, 6, 2023
5SPQ	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with FRESH00014134848 - (R) isomer 分子名称: (3R)-1-[(4-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)acetyl]-3-methylpyrrolidine-3-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
4US6	New Crystal Form of Glucose Isomerase Grown in Short Peptide Supramolecular Hydrogels 分子名称: CALCIUM ION, GLYCEROL, MAGNESIUM ION, ... 著者 Gavira, J.A, Conejero-Muriel, M, Diaz-Mochon, J.J, Alvarez de Cienfuegos, L. 登録日 2014-07-03 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Influence of the Chirality of Short Peptide Supramolecular Hydrogels in Protein Crystallogenesis. Chem.Commun.(Camb.), 51, 2015
4V3O	Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. 分子名称: ACETATE ION, CALCIUM ION, YIII_M5_AII 著者 Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. 登録日 2014-10-20 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects Acta Crystallogr.,Sect.D, 72, 2016
8HGV	Crystal structure of monoalkyl phthalate hydrolase MehpH 分子名称: Monoethylhexylphthalate hydrolase 著者 Zhang, Z.M, Wang, Y.J, Chen, Y.B. 登録日 2022-11-15 公開日 2023-03-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.30006242 Å) 主引用文献 Molecular insights into the catalytic mechanism of plasticizer degradation by a monoalkyl phthalate hydrolase. Commun Chem, 6, 2023
5SPW	PanDDA analysis group deposition -- Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with FRESH00004674769 - (R,S,R) isomer 分子名称: (1R,5S,6R)-3-(7H-purin-6-yl)-3-azabicyclo[3.2.2]nonane-6-carboxylic acid, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-06-09 公開日 2022-07-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2. Proc.Natl.Acad.Sci.USA, 120, 2023
4US8	Aldehyde Oxidoreductase from Desulfovibrio gigas (MOP), soaked with benzaldehyde 分子名称: (MOLYBDOPTERIN-CYTOSINE DINUCLEOTIDE-S,S)-DIOXO-AQUA-MOLYBDENUM(V), ALDEHYDE OXIDOREDUCTASE, BICARBONATE ION, ... 著者 Correia, H.D, Romao, M.J, Santos-Silva, T. 登録日 2014-07-03 公開日 2014-10-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Aromatic Aldehydes at the Active Site of Aldehyde Oxidoreductase from Desulfovibrio Gigas: Reactivity and Molecular Details of the Enzyme-Substrate and Enzyme-Product Interaction. J.Biol.Inorg.Chem., 20, 2015
8HHT	Crystal structure of the SARS-CoV-2 main protease in complex with Hit-1 分子名称: 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, ~{N}-[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(1,3-thiazol-2-ylmethylamino)butan-2-yl]benzamide 著者 Zeng, R, Xie, L.W, Huang, C, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J. 登録日 2022-11-17 公開日 2023-03-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A new generation M pro inhibitor with potent activity against SARS-CoV-2 Omicron variants. Signal Transduct Target Ther, 8, 2023
2RU0	Solution structure of actinomycesin 分子名称: Arthropod defensin 著者 Umetsu, Y, Gao, B, Zhu, S, Ohki, S. 登録日 2013-10-17 公開日 2014-10-22 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution structure of actinomycesin To be Published
8HJ0	GPR21(m5) and G15 complex 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Chen, B, Lin, X. 登録日 2022-11-22 公開日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Cryo-EM structures of orphan GPR21 signaling complexes. Nat Commun, 14, 2023
4UTL	XenA - reduced - Y183F variant in complex with coumarin 分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, COUMARIN, SULFATE ION, ... 著者 Werther, T, Dobbek, H. 登録日 2014-07-21 公開日 2015-08-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.229 Å) 主引用文献 Redox-dependent substrate-cofactor interactions in the Michaelis-complex of a flavin-dependent oxidoreductase Nat Commun, 8, 2017
8GYW	Cryo-EM structure of human CEPT1 complexed with CDP-choline 分子名称: Choline/ethanolaminephosphotransferase 1, MAGNESIUM ION, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM 著者 Qian, H.W, Wang, Z.H. 登録日 2022-09-24 公開日 2023-03-22 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1. Nat Commun, 14, 2023
4UY6	Crystal structure of Histidine and SAH bound Histidine-specific methyltransferase EgtD from Mycobacterium smegmatis 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HISTIDINE, HISTIDINE-SPECIFIC METHYLTRANSFERASE EGTD, ... 著者 Jeong, J.H, Kim, Y.G. 登録日 2014-08-29 公開日 2014-10-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural Insights Into the Histidine Trimethylation Activity of Egtd from Mycobacterium Smegmatis. Biochem.Biophys.Res.Commun., 452, 2014
2RQ2	The solution structure of the N-terminal fragment of big defensin 分子名称: Big defensin 著者 Kouno, T, Mizuguchi, M, Aizawa, T, Shinoda, H, Demura, M, Kawabata, S, Kawano, K. 登録日 2009-01-07 公開日 2009-08-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 A novel beta-defensin structure: big defensin changes its N-terminal structure to associate with the target membrane Biochemistry, 48, 2009
8HCQ	Cryo-EM structure of endothelin1-bound ETAR-Gq complex 分子名称: Endothelin-1, Endothelin-1 receptor,Oplophorus-luciferin 2-monooxygenase catalytic subunit chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Yuan, Q, Jiang, Y, Xu, H.E, Ji, Y, Duan, J. 登録日 2022-11-02 公開日 2023-03-22 最終更新日 2023-10-04 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structural basis of peptide recognition and activation of endothelin receptors. Nat Commun, 14, 2023
2RUT	Solution structures of the DNA-binding domain (ZF2) of immune-related zinc-finger protein ZFAT 分子名称: ZINC ION, Zinc finger protein ZFAT 著者 Tochio, N, Umehara, T, Kigawa, T, Yokoyama, S. 登録日 2015-01-26 公開日 2015-04-08 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT. J Struct Funct Genomics, 16, 2015
4V3R	Designed armadillo repeat protein with 5 internal repeats, 2nd generation C-cap and 3rd generation N-cap. 分子名称: MAGNESIUM ION, YIII_M5_AII 著者 Reichen, C, Madhurantakam, C, Pluckthun, A, Mittl, P. 登録日 2014-10-20 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structures of Designed Armadillo-Repeat Proteins Show Propagation of Inter-Repeat Interface Effects Acta Crystallogr.,Sect.D, 72, 2016
8GY1	Crystal structure of Ag+ binding to Dendrorhynchus zhejiangensis ferritin 分子名称: Ferritin, GLYCEROL, SILVER ION 著者 Ming, T.H, Su, X.R, Huo, C.H. 登録日 2022-09-21 公開日 2023-03-29 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Biochemical Characterization of Silver/Copper Binding by Dendrorhynchus zhejiangensis Ferritin. Polymers (Basel), 15, 2023
4UYE	BROMODOMAIN OF HUMAN BRPF1 WITH N-1,3-dimethyl-2-oxo-6-(piperidin-1- yl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl-2-methoxybenzamide 分子名称: 1,2-ETHANEDIOL, N-[1,3-dimethyl-2-oxo-6-(piperidin-1-yl)-2,3-dihydro-1H-benzimidazol-5-yl]-2-methoxybenzamide, PEREGRIN 著者 Chung, C, Bamborough, P, Demont, E. 登録日 2014-08-30 公開日 2014-09-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 1,3-Dimethyl Benzimidazolones are Potent, Selective Inhibitors of the Brpf1 Bromodomain. Acs Med.Chem.Lett., 5, 2014

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