6ZEG
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![BU of 6zeg by Molmil](/molmil-images/mine/6zeg) | Structure of PP1-IRSp53 chimera [PP1(7-304) + linker (G/S)x9 + IRSp53(449-465)] bound to Phactr1 (516-580) | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE, MANGANESE (II) ION, ... | 著者 | Mouilleron, S, Treisman, R, Fedoryshchak, R, Lee, R, Butler, A.M, Prechova, M. | 登録日 | 2020-06-16 | 公開日 | 2020-09-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme. Elife, 9, 2020
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6ZFX
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![BU of 6zfx by Molmil](/molmil-images/mine/6zfx) | hSARM1 GraFix-ed | 分子名称: | (~{E})-4-methylnon-4-enedial, NAD(+) hydrolase SARM1 | 著者 | Sporny, M, Guez-Haddad, J, Khazma, T, Yaron, A, Dessau, M, Mim, C, Isupov, M.N, Zalk, R, Hons, M, Opatowsky, Y. | 登録日 | 2020-06-18 | 公開日 | 2020-11-18 | 最終更新日 | 2022-11-09 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Structural basis for SARM1 inhibition and activation under energetic stress. Elife, 9, 2020
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7OF2
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![BU of 7of2 by Molmil](/molmil-images/mine/7of2) | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with GTPBP6. | 分子名称: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | 著者 | Hillen, H.S, Lavdovskaia, E, Nadler, F, Hanitsch, E, Linden, A, Bohnsack, K.E, Urlaub, H, Richter-Dennerlein, R. | 登録日 | 2021-05-04 | 公開日 | 2021-06-02 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling. Nat Commun, 12, 2021
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2XI4
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![BU of 2xi4 by Molmil](/molmil-images/mine/2xi4) | Torpedo californica Acetylcholinesterase in Complex with Aflatoxin B1 (Orthorhombic Space Group) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, AFLATOXIN B1, ... | 著者 | Sanson, B, Colletier, J.P, Xu, Y, Lang, P.T, Jiang, H, Silman, I, Sussman, J.L, Weik, M. | 登録日 | 2010-06-28 | 公開日 | 2011-03-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Backdoor Opening Mechanism in Acetylcholinesterase Based on X-Ray Crystallography and Molecular Dynamics Simulations. Protein Sci., 20, 2011
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1MFQ
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![BU of 1mfq by Molmil](/molmil-images/mine/1mfq) | Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle | 分子名称: | 7S RNA of human SRP, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Kuglstatter, A, Oubridge, C, Nagai, K. | 登録日 | 2002-08-13 | 公開日 | 2002-09-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Induced structural changes of 7SL RNA during the assembly of human
signal recognition particle Nat.Struct.Biol., 9, 2002
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2XBG
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![BU of 2xbg by Molmil](/molmil-images/mine/2xbg) | |
1GR0
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![BU of 1gr0 by Molmil](/molmil-images/mine/1gr0) | myo-inositol 1-phosphate synthase from Mycobacterium tuberculosis in complex with NAD and zinc. | 分子名称: | CACODYLATE ION, INOSITOL-3-PHOSPHATE SYNTHASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Norman, R.A, Murray-Rust, J, McDonald, N.Q, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2001-12-10 | 公開日 | 2002-03-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of Inositol 1-Phosphate Synthase from Mycobacterium Tuberculosis, a Key Enzyme in Phosphatidylinositol Synthesis Structure, 10, 2002
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1I8K
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![BU of 1i8k by Molmil](/molmil-images/mine/1i8k) | CRYSTAL STRUCTURE OF DSFV MR1 IN COMPLEX WITH THE PEPTIDE ANTIGEN OF THE MUTANT EPIDERMAL GROWTH FACTOR RECEPTOR, EGFRVIII, AT LIQUID NITROGEN TEMPERATURE | 分子名称: | EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV HEAVY CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY MR1SCFV LIGHT CHAIN, EPIDERMAL GROWTH FACTOR RECEPTOR, ... | 著者 | Landry, R.C, Klimowicz, A.C, Lavictoire, S.J, Borisova, S, Kottachchi, D.T, Lorimer, I.A, Evans, S.V. | 登録日 | 2001-03-14 | 公開日 | 2002-03-14 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Antibody recognition of a conformational epitope in a peptide antigen: Fv-peptide complex of an antibody fragment specific for the mutant EGF receptor, EGFRvIII. J.Mol.Biol., 308, 2001
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1I39
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![BU of 1i39 by Molmil](/molmil-images/mine/1i39) | RNASE HII FROM ARCHAEOGLOBUS FULGIDUS | 分子名称: | RIBONUCLEASE HII | 著者 | Chapados, B.R, Chai, Q, Hosfield, D.J, Qiu, J, Shen, B, Tainer, J.A. | 登録日 | 2001-02-13 | 公開日 | 2001-04-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication. J.Mol.Biol., 307, 2001
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6Z01
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![BU of 6z01 by Molmil](/molmil-images/mine/6z01) | DNA Topoisomerase | 分子名称: | CHLORIDE ION, DNA topoisomerase I | 著者 | Takahashi, T.S, Gadelle, D, Forterre, P, Mayer, C, Petrella, S. | 登録日 | 2020-05-07 | 公開日 | 2021-11-17 | 最終更新日 | 2023-05-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states. Nat Commun, 13, 2022
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6Z03
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![BU of 6z03 by Molmil](/molmil-images/mine/6z03) | DNA Topoisomerase | 分子名称: | DNA topoisomerase I | 著者 | Takahashi, T.S, Gadelle, D, Forterre, P, Mayer, C, Petrella, S. | 登録日 | 2020-05-07 | 公開日 | 2021-11-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states. Nat Commun, 13, 2022
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1L9H
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![BU of 1l9h by Molmil](/molmil-images/mine/1l9h) | Crystal structure of bovine rhodopsin at 2.6 angstroms RESOLUTION | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEPTANE-1,2,3-TRIOL, MERCURY (II) ION, ... | 著者 | Okada, T, Fujiyoshi, Y, Silow, M, Navarro, J, Landau, E.M, Shichida, Y. | 登録日 | 2002-03-23 | 公開日 | 2002-05-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography. Proc.Natl.Acad.Sci.USA, 99, 2002
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1D62
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![BU of 1d62 by Molmil](/molmil-images/mine/1d62) | |
7OYL
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![BU of 7oyl by Molmil](/molmil-images/mine/7oyl) | Phosphoglucose isomerase of Aspergillus fumigatus in complexed with Glucose-6-phosphate | 分子名称: | 6-O-phosphono-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | 著者 | Raimi, O.G, Yan, K, Fang, W, van Aalten, D.M.F. | 登録日 | 2021-06-24 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis. Mbio, 13, 2022
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2WWY
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![BU of 2wwy by Molmil](/molmil-images/mine/2wwy) | Structure of human RECQ-like helicase in complex with a DNA substrate | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*DA DG DC DG DT DC DG DA DG DA DT DC DCP)-3', ATP-DEPENDENT DNA HELICASE Q1, ... | 著者 | Pike, A.C.W, Zhang, Y, Schnecke, C, Chaikuad, A, Krojer, T, Cooper, C.D.O, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2009-10-30 | 公開日 | 2009-12-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Recq1 Helicase-Driven DNA Unwinding, Annealing, and Branch Migration: Insights from DNA Complex Structures Proc.Natl.Acad.Sci.USA, 112, 2015
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1LKT
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1LJZ
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![BU of 1ljz by Molmil](/molmil-images/mine/1ljz) | NMR structure of an AChR-peptide (Torpedo Californica, alpha-subunit residues 182-202) in complex with alpha-Bungarotoxin | 分子名称: | Acetylcholine receptor protein, alpha-Bungarotoxin | 著者 | Samson, A.O, Scherf, T, Eisenstein, M, Chill, J.H, Anglister, J. | 登録日 | 2002-04-23 | 公開日 | 2002-07-17 | 最終更新日 | 2013-07-24 | 実験手法 | SOLUTION NMR | 主引用文献 | The mechanism for acetylcholine receptor inhibition by alpha-neurotoxins and species-specific resistance to alpha-bungarotoxin revealed by NMR. Neuron, 35, 2002
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1I9X
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1D5F
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![BU of 1d5f by Molmil](/molmil-images/mine/1d5f) | STRUCTURE OF E6AP: INSIGHTS INTO UBIQUITINATION PATHWAY | 分子名称: | E6AP HECT CATALYTIC DOMAIN, E3 LIGASE | 著者 | Huang, L, Kinnucan, E, Wang, G, Beaudenon, S, Howley, P.M, Huibregtse, J.M, Pavletich, N.P. | 登録日 | 1999-10-07 | 公開日 | 1999-11-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade. Science, 286, 1999
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1LD7
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![BU of 1ld7 by Molmil](/molmil-images/mine/1ld7) | Co-crystal structure of Human Farnesyltransferase with farnesyldiphosphate and inhibitor compound 66 | 分子名称: | (20S)-19,20,22,23-TETRAHYDRO-19-OXO-5H,21H-18,20-ETHANO-12,14-ETHENO-6,10-METHENOBENZ[D]IMIDAZO[4,3-L][1,6,9,13]OXATRIA ZACYCLONOADECOSINE-9-CARBONITRILE, FARNESYL DIPHOSPHATE, ZINC ION, ... | 著者 | Taylor, J.S, Terry, K.L, Beese, L.S. | 登録日 | 2002-04-08 | 公開日 | 2002-06-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. J.Med.Chem., 45, 2002
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1LN6
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![BU of 1ln6 by Molmil](/molmil-images/mine/1ln6) | STRUCTURE OF BOVINE RHODOPSIN (Metarhodopsin II) | 分子名称: | RETINAL, RHODOPSIN | 著者 | Choi, G, Landin, J, Galan, J.F, Birge, R.R, Albert, A.D, Yeagle, P.L. | 登録日 | 2002-05-03 | 公開日 | 2002-07-10 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural studies of metarhodopsin II, the activated form of the G-protein coupled receptor, rhodopsin. Biochemistry, 41, 2002
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2Y2U
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![BU of 2y2u by Molmil](/molmil-images/mine/2y2u) | Nonaged form of Mouse Acetylcholinesterase inhibited by VX-Update | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ACETYLCHOLINESTERASE, ... | 著者 | Akfur, C, Artursson, E, Ekstrom, F. | 登録日 | 2010-12-16 | 公開日 | 2011-11-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Methylphosphonate Adducts of Acetylcholinesterase Investigated by Time Correlated Single Photon Counting and X-Ray Crystallography To be Published
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1CEK
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![BU of 1cek by Molmil](/molmil-images/mine/1cek) | THREE-DIMENSIONAL STRUCTURE OF THE MEMBRANE-EMBEDDED M2 CHANNEL-LINING SEGMENT FROM THE NICOTINIC ACETYLCHOLINE RECEPTOR BY SOLID-STATE NMR SPECTROSCOPY | 分子名称: | PROTEIN (ACETYLCHOLINE RECEPTOR M2) | 著者 | Marassi, F.M, Gesell, J.J, Kim, Y, Valente, A.P, Oblatt-Montal, M, Montal, M, Opella, S.J. | 登録日 | 1999-03-09 | 公開日 | 1999-03-11 | 最終更新日 | 2023-12-27 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy. Nat.Struct.Biol., 6, 1999
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6XDR
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![BU of 6xdr by Molmil](/molmil-images/mine/6xdr) | Escherichia coli transcription-translation complex B (TTC-B) containing an 27 nt long mRNA spacer, NusG, and fMet-tRNAs at E-site and P-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Wang, C, Su, M, Ebright, R.H. | 登録日 | 2020-06-11 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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6XD0
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![BU of 6xd0 by Molmil](/molmil-images/mine/6xd0) | Dengue serotype 3 RNA-dependent RNA polymerase bound to NITD-434 | 分子名称: | 2-[({2-[(2,6-dichlorophenyl)amino]phenyl}acetyl)amino]-2,3-dihydro-1H-indene-2-carboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Arora, R, Benson, T.E, Liew, C.W, Lescar, J. | 登録日 | 2020-06-09 | 公開日 | 2020-09-23 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.012 Å) | 主引用文献 | Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies. J.Virol., 94, 2020
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