6XD0

Dengue serotype 3 RNA-dependent RNA polymerase bound to NITD-434

Summary for 6XD0

Entry DOI	10.2210/pdb6xd0/pdb
Descriptor	RNA-dependent RNA polymerase, ZINC ION, GLYCEROL, ... (6 entities in total)
Functional Keywords	dengue rdrp, transferase
Biological source	Dengue virus 3
Total number of polymer chains	1
Total formula weight	74699.54
Authors	Arora, R.,Benson, T.E.,Liew, C.W.,Lescar, J. (deposition date: 2020-06-09, release date: 2020-09-23, Last modification date: 2021-10-06)
Primary citation	Arora, R.,Liew, C.W.,Soh, T.S.,Otoo, D.A.,Seh, C.C.,Yue, K.,Nilar, S.,Wang, G.,Yokokawa, F.,Noble, C.G.,Chen, Y.L.,Shi, P.Y.,Lescar, J.,Smith, T.M.,Benson, T.E.,Lim, S.P. Two RNA Tunnel Inhibitors Bind in Highly Conserved Sites in Dengue Virus NS5 Polymerase: Structural and Functional Studies. J.Virol., 94:-, 2020 Cited by PubMed: 32907977 DOI: 10.1128/JVI.01130-20 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.012 Å)

Structure validation