6ZEG

Structure of PP1-IRSp53 chimera [PP1(7-304) + linker (G/S)x9 + IRSp53(449-465)] bound to Phactr1 (516-580)

Summary for 6ZEG

Entry DOI	10.2210/pdb6zeg/pdb
Descriptor	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit,Brain-specific angiogenesis inhibitor 1-associated protein 2, Phosphatase and actin regulator, MANGANESE (II) ION, ... (7 entities in total)
Functional Keywords	pp1, phosphatase, phactr, rpel, hydrolase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	92762.42
Authors	Mouilleron, S.,Treisman, R.,Fedoryshchak, R.,Lee, R.,Butler, A.M.,Prechova, M. (deposition date: 2020-06-16, release date: 2020-09-30, Last modification date: 2024-01-24)
Primary citation	Fedoryshchak, R.O.,Prechova, M.,Butler, A.,Lee, R.,O'Reilly, N.,Flynn, H.R.,Snijders, A.P.,Eder, N.,Ultanir, S.,Mouilleron, S.,Treisman, R. Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme. Elife, 9:-, 2020 Cited by PubMed: 32975518 DOI: 10.7554/eLife.61509 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.09 Å)

Structure validation