PDB: 46984 件ウェブページステータス検索Chemie searchBIRD

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6OSK	RF1 accommodated 70S complex at 60 ms 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. 登録日 2019-05-01 公開日 2019-06-26 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
6OGF	70S termination complex with RF2 bound to the UGA codon. Partially rotated ribosome with RF2 bound (Structure III). 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. 登録日 2019-04-02 公開日 2019-09-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
6ORE	Release complex 70S 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Fu, Z. 登録日 2019-04-30 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
3K1F	Crystal structure of RNA Polymerase II in complex with TFIIB 分子名称: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... 著者 Kostrewa, D, Zeller, M.E, Armache, K.-J, Seizl, M, Leike, K, Thomm, M, Cramer, P. 登録日 2009-09-27 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (4.3 Å) 主引用文献 RNA polymerase II-TFIIB structure and mechanism of transcription initiation. Nature, 462, 2009
5LKS	Structure-function insights reveal the human ribosome as a cancer target for antibiotics 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Myasnikov, A.G, Natchiar, S.K, Nebout, M, Hazemann, I, Imbert, V, Khatter, H, Peyron, J.-F, Klaholz, B.P. 登録日 2016-07-23 公開日 2017-04-26 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure-function insights reveal the human ribosome as a cancer target for antibiotics. Nat Commun, 7, 2016
5LI0	70S ribosome from Staphylococcus aureus 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Khusainov, I, Vicens, Q, Bochler, A, Grosse, F, Myasnikov, A, Menetret, J.F, Chicher, J, Marzi, S, Romby, P, Yusupova, G, Yusupov, M, Hashem, Y. 登録日 2016-07-13 公開日 2016-12-28 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structure of the 70S ribosome from human pathogen Staphylococcus aureus. Nucleic Acids Res., 44, 2016
7JQB	SARS-CoV-2 Nsp1 and rabbit 40S ribosome complex 分子名称: 40S ribosomal protein S21, 40S ribosomal protein S24, 40S ribosomal protein S26, ... 著者 Yuan, S, Xiong, Y. 登録日 2020-08-10 公開日 2020-12-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. Mol.Cell, 80, 2020
7JQL	Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-001, mRNA, and deacylated P-site tRNA at 3.00A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M. 登録日 2020-08-11 公開日 2020-08-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens. J.Med.Chem., 63, 2020
5LMT	Structure of bacterial 30S-IF1-IF3-mRNA-tRNA translation pre-initiation complex(state-3) 分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Hussain, T, Llacer, J.L, Wimberly, B.T, Ramakrishnan, V. 登録日 2016-08-01 公開日 2016-10-05 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (4.15 Å) 主引用文献 Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation. Cell, 167, 2016
3J1N	Cryo-EM map of a yeast minimal preinitiation complex interacting with the Mediator Head module 分子名称: DNA-directed RNA polymerase II subunit RPABC1, DNA-directed RNA polymerase II subunit RPABC2, DNA-directed RNA polymerase II subunit RPABC3, ... 著者 Asturias, F.J, Imasaki, T. 登録日 2012-03-29 公開日 2013-03-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (16 Å) 主引用文献 Interaction of the mediator head module with RNA polymerase II. Structure, 20, 2012
8G38	Time-resolved cryo-EM study of the 70S recycling by the HflX:3rd Intermediate 分子名称: 16S, 23S, 30S ribosomal protein S10, ... 著者 Bhattacharjee, S, Brown, P.Z, Frank, J. 登録日 2023-02-07 公開日 2023-12-06 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
7DVQ	Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... 著者 Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. 登録日 2021-01-14 公開日 2021-03-31 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Structure of the activated human minor spliceosome. Science, 371, 2021
8G2U	Time-resolved cryo-EM study of the 70S recycling by the HflX:control-apo-70S at 900ms 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Bhattacharjee, S, Brown, P.Z, Frank, J. 登録日 2023-02-06 公開日 2023-12-06 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
6OSQ	RF1 accommodated state bound Release complex 70S at long incubation time point 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. 登録日 2019-05-02 公開日 2019-06-26 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
8G34	Time-resolved cryo-EM study of the 70S recycling by the HflX:1st intermediate 分子名称: 16S, 23S, 30S ribosomal protein S10, ... 著者 Bhattacharjee, S, Brown, P.Z, Frank, J. 登録日 2023-02-06 公開日 2023-12-06 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
5LEJ	The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a 30-bp operator PrfA-box motif 分子名称: DNA (30-MER), Listeriolysin regulatory protein 著者 Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E. 登録日 2016-06-29 公開日 2016-12-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
6OGI	70S termination complex with RF2 bound to the UAG codon. Rotated ribosome conformation (Structure V) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Demo, G, Loveland, A.B, Xu, C, Korostelev, A.A. 登録日 2019-04-02 公開日 2019-09-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Extensive ribosome and RF2 rearrangements during translation termination. Elife, 8, 2019
5LRS	The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione and a 30-bp operator PrfA-box motif 分子名称: DNA (30-MER), GLUTATHIONE, Listeriolysin positive regulatory factor A 著者 Hall, M, Grundstrom, C, Begum, A, Lindberg, M, Sauer, U.H, Almqvist, F, Johansson, J, Sauer-Eriksson, A.E. 登録日 2016-08-19 公開日 2016-12-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
6OUO	RF2 accommodated state bound 70S complex at long incubation time 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Fu, Z, Indrisiunaite, G, Kaledhonkar, S, Shah, B, Sun, M, Chen, B, Grassucci, R.A, Ehrenberg, M, Frank, J. 登録日 2019-05-05 公開日 2019-06-19 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy. Nat Commun, 10, 2019
7K93	DENV2 NS1 in complex with neutralizing 2B7 single chain Fab variable region (scFv) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 single chain fab variable region, Non-structural protein 1 著者 Akey, D.L, Smith, J.L. 登録日 2020-09-28 公開日 2020-12-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction. Science, 371, 2021
6P5J	Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 2) 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
5K0I	mpges1 bound to an inhibitor 分子名称: 1,5-anhydro-2,3,4-trideoxy-3-{[(4S)-3,3-dimethyl-1-(8-methylquinolin-2-yl)piperidine-4-carbonyl]amino}-D-erythro-hexitol, GLUTATHIONE, Prostaglandin E synthase, ... 著者 Luz, J.G, Kuklish, S.L. 登録日 2016-05-17 公開日 2016-09-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
7JQM	Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-002, mRNA, and deacylated P-site tRNA at 3.05A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M. 登録日 2020-08-11 公開日 2020-08-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens. J.Med.Chem., 63, 2020
7K5I	SARS-COV-2 nsp1 in complex with human 40S ribosome 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Wang, L, Shi, M, Wu, H. 登録日 2020-09-16 公開日 2020-10-14 最終更新日 2021-03-17 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 SARS-CoV-2 Nsp1 suppresses host but not viral translation through a bipartite mechanism. Biorxiv, 2020
5LMR	Structure of bacterial 30S-IF1-IF3-mRNA-tRNA translation pre-initiation complex(state-2B) 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Hussain, T, Llacer, J.L, Wimberly, B.T, Ramakrishnan, V. 登録日 2016-08-01 公開日 2016-10-05 最終更新日 2019-10-02 実験手法 ELECTRON MICROSCOPY (4.45 Å) 主引用文献 Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation. Cell, 167, 2016

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