5LRS

The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with glutathione and a 30-bp operator PrfA-box motif

Summary for 5LRS

Entry DOI	10.2210/pdb5lrs/pdb
Related	2beo
Descriptor	Listeriolysin positive regulatory factor A, DNA (30-MER), GLUTATHIONE, ... (5 entities in total)
Functional Keywords	transcription regulator, dna binding, activation, glutathione, listeria monocytogenes, transcription
Biological source	Listeria monocytogenes More
Total number of polymer chains	4
Total formula weight	73715.38
Authors	Hall, M.,Grundstrom, C.,Begum, A.,Lindberg, M.,Sauer, U.H.,Almqvist, F.,Johansson, J.,Sauer-Eriksson, A.E. (deposition date: 2016-08-19, release date: 2016-12-07, Last modification date: 2024-01-17)
Primary citation	Hall, M.,Grundstrom, C.,Begum, A.,Lindberg, M.J.,Sauer, U.H.,Almqvist, F.,Johansson, J.,Sauer-Eriksson, A.E. Structural basis for glutathione-mediated activation of the virulence regulatory protein PrfA in Listeria. Proc. Natl. Acad. Sci. U.S.A., 113:14733-14738, 2016 Cited by PubMed: 27930316 DOI: 10.1073/pnas.1614028114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation