PDB: 37932 件ウェブページステータス検索Chemie searchBIRD

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7A4H	Aquifex aeolicus lumazine synthase-derived nucleocapsid variant NC-2 (180-mer) 分子名称: Antitermination protein N,6,7-dimethyl-8-ribityllumazine synthase,6,7-dimethyl-8-ribityllumazine synthase 著者 Tetter, S, Hilvert, D. 登録日 2020-08-19 公開日 2021-06-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein. Science, 372, 2021
7A4G	Aquifex aeolicus lumazine synthase-derived nucleocapsid variant NC-1 (180-mer) 分子名称: Antitermination protein N,6,7-dimethyl-8-ribityllumazine synthase,6,7-dimethyl-8-ribityllumazine synthase 著者 Tetter, S, Hilvert, D. 登録日 2020-08-19 公開日 2021-06-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Evolution of a virus-like architecture and packaging mechanism in a repurposed bacterial protein. Science, 372, 2021
5QGM	PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with OX-160 分子名称: 1-(4'-methoxy[1,1'-biphenyl]-2-yl)pyrrolidin-2-one, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Krojer, T, Talon, R, Fairhead, M, Diaz Saez, L, Bradley, A.R, Aimon, A, Collins, P, Brandao-Neto, J, Douangamath, A, Ruda, G.F, Szommer, T, Srikannathasan, V, Elkins, J, Spencer, J, London, N, Nelson, A, Brennan, P.E, Huber, K, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2018-05-15 公開日 2019-03-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
5QH0	PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with NUOOA000180 分子名称: 2-(3-hydroxyphenyl)-N-(pyridin-3-yl)acetamide, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Krojer, T, Talon, R, Fairhead, M, Diaz Saez, L, Bradley, A.R, Aimon, A, Collins, P, Brandao-Neto, J, Douangamath, A, Ruda, G.F, Szommer, T, Srikannathasan, V, Elkins, J, Spencer, J, London, N, Nelson, A, Brennan, P.E, Huber, K, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2018-05-15 公開日 2019-03-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
7UX2	cryo-EM structure of the Raptor-TFEB-Rag-Ragulator complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Cui, Z, Hurley, J. 登録日 2022-05-04 公開日 2022-11-30 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023
7UXC	cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex with symmetry expansion 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Cui, Z, Hurley, J. 登録日 2022-05-05 公開日 2022-11-30 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023
7UXH	cryo-EM structure of the mTORC1-TFEB-Rag-Ragulator complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Cui, Z, Hurley, J. 登録日 2022-05-05 公開日 2022-11-30 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. Nature, 614, 2023
7UFJ	Structure of human MR1-ethylvanillin in complex with human MAIT A-F7 TCR 分子名称: 3-ethoxy-4-hydroxybenzaldehyde, ACETATE ION, Beta-2-microglobulin, ... 著者 Wang, C.J, Rossjohn, J, Le Nours, J. 登録日 2022-03-22 公開日 2022-12-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Quantitative affinity measurement of small molecule ligand binding to Major Histocompatibility Complex class-I related protein 1 MR1. J.Biol.Chem., 298, 2022
8J6K	Crystal structure of pro-interleukin-18 and caspase-4 complex 分子名称: Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ... 著者 Sun, Q, Hou, Y.J, Ding, J. 登録日 2023-04-26 公開日 2023-11-29 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.12 Å) 主引用文献 Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome. Nature, 624, 2023
5QGL	PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with FMOPL000275a 分子名称: 3,4,5-trimethoxybenzoic acid, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Krojer, T, Talon, R, Fairhead, M, Diaz Saez, L, Bradley, A.R, Aimon, A, Collins, P, Brandao-Neto, J, Douangamath, A, Ruda, G.F, Szommer, T, Srikannathasan, V, Elkins, J, Spencer, J, London, N, Nelson, A, Brennan, P.E, Huber, K, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2018-05-15 公開日 2019-03-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
5QGX	PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with NUOOA000155 分子名称: ACETATE ION, DIMETHYL SULFOXIDE, N-(3-chlorophenyl)-2-(4-methoxyphenyl)acetamide, ... 著者 Krojer, T, Talon, R, Fairhead, M, Diaz Saez, L, Bradley, A.R, Aimon, A, Collins, P, Brandao-Neto, J, Douangamath, A, Ruda, G.F, Szommer, T, Srikannathasan, V, Elkins, J, Spencer, J, London, N, Nelson, A, Brennan, P.E, Huber, K, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2018-05-15 公開日 2019-03-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) To Be Published
5QHA	PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with PCM-0102951 分子名称: ACETATE ION, N-[1-(2,3-dihydro-1,4-benzodioxin-6-yl)cyclopentyl]acetamide, Peroxisomal coenzyme A diphosphatase NUDT7 著者 Krojer, T, Talon, R, Fairhead, M, Diaz Saez, L, Bradley, A.R, Aimon, A, Collins, P, Brandao-Neto, J, Douangamath, A, Ruda, G.F, Szommer, T, Srikannathasan, V, Elkins, J, Spencer, J, London, N, Nelson, A, Brennan, P.E, Huber, K, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2018-09-21 公開日 2019-03-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 PanDDA analysis group deposition To Be Published
1H2U	Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppG 分子名称: 20 KDA NUCLEAR CAP BINDING PROTEIN, 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, 80 KDA NUCLEAR CAP BINDING PROTEIN, ... 著者 Mazza, C, Segref, A, Mattaj, I.W, Cusack, S. 登録日 2002-08-16 公開日 2002-10-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Large-Scale Induced Fit Recognition of an M(7)Gpppg CAP Analogue by the Human Nuclear CAP-Binding Complex Embo J., 21, 2002
1NZA	Divalent cation tolerance protein (Cut A1) from thermus thermophilus HB8 分子名称: CHLORIDE ION, Divalent cation tolerance protein, GLYCEROL, ... 著者 Bagautdinov, B, Miyano, M, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-02-17 公開日 2003-03-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The structures of the CutA1 proteins from Thermus thermophilus and Pyrococcus horikoshii: characterization of metal-binding sites and metal-induced assembly. Acta Crystallogr.,Sect.F, 70, 2014
1O0F	RNASE A in complex with 3',5'-ADP 分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Ribonuclease pancreatic 著者 Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. 登録日 2003-02-21 公開日 2003-12-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors PROTEIN SCI., 12, 2003
1O0M	Ribonuclease A in complex with uridine-2'-phosphate 分子名称: PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER, Ribonuclease pancreatic 著者 Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. 登録日 2003-02-24 公開日 2003-12-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors PROTEIN SCI., 12, 2003
5NGT	Crystal structure of human MTH1 in complex with inhibitor 7-(furan-2-yl)-5-methyl-1,3-benzoxazol-2-amine 分子名称: 7,8-dihydro-8-oxoguanine triphosphatase, 7-(furan-2-yl)-5-methyl-1,3-benzoxazol-2-amine, SULFATE ION 著者 Gustafsson, R, Rudling, A, Almlof, I, Homan, E, Scobie, M, Warpman Berglund, U, Helleday, T, Carlsson, J, Stenmark, P. 登録日 2017-03-20 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space. J. Med. Chem., 60, 2017
1H2T	Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppG 分子名称: 20 KDA NUCLEAR CAP BINDING PROTEIN, 7N-METHYL-8-HYDROGUANOSINE-5'-MONOPHOSPHATE, 80 KDA NUCLEAR CAP BINDING PROTEIN, ... 著者 Mazza, C, Segref, A, Mattaj, I.W, Cusack, S. 登録日 2002-08-16 公開日 2002-10-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Large-Scale Induced Fit Recognition of an M(7)Gpppg CAP Analogue by the Human Nuclear CAP-Binding Complex Embo J., 21, 2002
8CCI	Crystal structure of Mycobacterium smegmatis thioredoxin reductase 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, MAGNESIUM ION, ... 著者 Fuesser, F.T, Koch, O, Kuemmel, D. 登録日 2023-01-27 公開日 2023-07-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Novel starting points for fragment-based drug design against mycobacterial thioredoxin reductase identified using crystallographic fragment screening. Acta Crystallogr D Struct Biol, 79, 2023
7U21	Human Class I MHC HLA-A2 in complex with AVGSYVYSV peptide 分子名称: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... 著者 Weiss, L.I, Baker, B.M. 登録日 2022-02-22 公開日 2022-06-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Physicochemical Heuristics for Identifying High Fidelity, Near-Native Structural Models of Peptide/MHC Complexes. Front Immunol, 13, 2022
7A0S	50S Deinococcus radiodurans ribosome bounded with mycinamicin I 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Breiner, E, Eyal, Z, Matzov, D, Halfon, Y, Cimicata, G, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. 登録日 2020-08-10 公開日 2021-08-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Ribosome-binding and anti-microbial studies of the mycinamicins, 16-membered macrolide antibiotics from Micromonospora griseorubida. Nucleic Acids Res., 49, 2021
8DS8	Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide 分子名称: Histone H3.1, Trinucleotide repeat-containing gene 18 protein 著者 Song, J.K, Lu, J.W. 登録日 2022-07-21 公開日 2023-08-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons. Nature, 623, 2023
7R72	State E1 nucleolar 60S ribosome biogenesis intermediate - Spb4 local model 分子名称: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... 著者 Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. 登録日 2021-06-24 公開日 2022-11-09 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
7R7A	State E1 nucleolar 60S ribosome biogenesis intermediate - Composite model 分子名称: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... 著者 Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. 登録日 2021-06-24 公開日 2022-11-09 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
1H2V	Structure of the human nuclear cap-binding-complex (CBC) 分子名称: 20 KDA NUCLEAR CAP BINDING PROTEIN, 80 KDA NUCLEAR CAP BINDING PROTEIN 著者 Mazza, C, Segref, A, Mattaj, I.W, Cusack, S. 登録日 2002-08-16 公開日 2002-10-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Large-Scale Induced Fit Recognition of an M(7)Gpppg CAP Analogue by the Human Nuclear CAP-Binding Complex Embo J., 21, 2002

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