1H2T

Structure of the human nuclear cap-binding-complex (CBC) in complex with a cap analogue m7GpppG

Summary for 1H2T

Related1H6K 1H2U 1H2V
Descriptor80 KDA NUCLEAR CAP BINDING PROTEIN, 20 KDA NUCLEAR CAP BINDING PROTEIN, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywordsm7gcap, cap-binding-complex, rnp domain, mif4g domain, rna maturation, rna export, nuclear protein, rna-binding
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total molecular weight102685.84
Authors
Mazza, C.,Segref, A.,Mattaj, I.W.,Cusack, S. (deposition date: 2002-08-16, release date: 2002-10-17, Last modification date: 2019-04-03)
Primary citation
Mazza, C.,Segref, A.,Mattaj, I.W.,Cusack, S.
Large-Scale Induced Fit Recognition of an M(7)Gpppg CAP Analogue by the Human Nuclear CAP-Binding Complex
Embo J., 21:5548-, 2002
PubMed: 12374755 (PDB entries with the same primary citation)
DOI: 10.1093/EMBOJ/CDF538
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.26210 0.2% 2.1% 12.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25