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3FRW
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Crystal structure of putative TrpR protein from Ruminococcus obeum
分子名称: ACETATE ION, Putative Trp repressor protein
著者Osipiuk, J, Keigher, L, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-01-08
公開日2009-01-20
最終更新日2020-01-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献X-ray crystal structure of putative TrpR protein from Ruminococcus obeum.
To be Published
4JFJ
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Increasing the Efficiency Efficiency of Ligands for the FK506-Binding Protein 51 by Conformational Control: Complex of FKBP51 with compound (1S,6R)-10-(1,3-benzothiazol-6-ylsulfonyl)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-3,10-diazabicyclo[4.3.1]decan-2-one
分子名称: (1S,6R)-10-(1,3-benzothiazol-6-ylsulfonyl)-3-[2-(3,4-dimethoxyphenoxy)ethyl]-3,10-diazabicyclo[4.3.1]decan-2-one, Peptidyl-prolyl cis-trans isomerase FKBP5
著者Wang, Y, Kirschner, A, Fabian, A, Gopalakrishnan, R, Kress, C, Hoogeland, B, Koch, U, Kozany, C, Bracher, A, Hausch, F.
登録日2013-02-28
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control.
J.Med.Chem., 56, 2013
4JG6
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RSK2 CTD bound to 2-cyano-3-(1H-indazol-5-yl)acrylamide
分子名称: (2S)-2-cyano-3-(1H-indazol-5-yl)propanamide, Ribosomal protein S6 kinase alpha-3, SODIUM ION
著者Miller, R.M, Paavilainen, V.O, Krishnan, S, Serafimova, I.M, Taunton, J.
登録日2013-02-28
公開日2013-04-10
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Electrophilic fragment-based design of reversible covalent kinase inhibitors.
J.Am.Chem.Soc., 135, 2013
3OXF
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BU of 3oxf by Molmil
Human lysine methyltransferase Smyd3 in complex with AdoHcy (Form I)
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, SET and MYND domain-containing protein 3, ZINC ION
著者Xu, S, Wu, J, Sun, B, Zhong, C, Ding, J.
登録日2010-09-21
公開日2011-02-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding.
Nucleic Acids Res., 39, 2011
4NXM
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BU of 4nxm by Molmil
Crystal Structure of the 30S ribosomal subunit from a GidB (RsmG) mutant of Thermus thermophilus (HB8)
分子名称: 16S rRNA, MAGNESIUM ION, ZINC ION, ...
著者Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G.
登録日2013-12-09
公開日2014-05-21
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献A structural basis for streptomycin resistance
To be Published
4JGE
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BU of 4jge by Molmil
Crystal structure of red fluorescent gene-engineered variant with improved folding - lanRFP_delS83 (Branchiostoma lanceolatum)
分子名称: GLYCEROL, Red fluorescent protein blFP-R5
著者Pletnev, V.Z, Pletneva, N.V, Pletnev, S.V.
登録日2013-03-01
公開日2013-09-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structure of the red fluorescent protein from a lancelet (Branchiostoma lanceolatum): a novel GYG chromophore covalently bound to a nearby tyrosine.
Acta Crystallogr.,Sect.D, 69, 2013
2NZ5
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BU of 2nz5 by Molmil
Structure and Function Studies of Cytochrome P450 158A1 from Streptomyces coelicolor A3(2)
分子名称: Cytochrome P450 CYP158A1, PROTOPORPHYRIN IX CONTAINING FE, naphthalene-1,2,4,5,7-pentol
著者Zhao, B, Lamb, D.C, Kelly, S.L, Waterman, M.R.
登録日2006-11-22
公開日2007-07-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2.
Biochemistry, 46, 2007
2NZT
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Crystal structure of human hexokinase II
分子名称: 6-O-phosphono-beta-D-glucopyranose, Hexokinase-2, UNKNOWN ATOM OR ION, ...
著者Rabeh, W.M, Zhu, H, Nedyalkova, L, Tempel, W, Wasney, G, Landry, R, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2006-11-25
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation.
Biosci.Rep., 38, 2018
4JH3
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Crystal Structure of FosB from Bacillus cereus with Zinc and Fosfomycin
分子名称: FORMIC ACID, FOSFOMYCIN, GLYCEROL, ...
著者Thompson, M.K, Harp, J, Keithly, M.E, Jagessar, K, Cook, P.D, Armstrong, R.N.
登録日2013-03-04
公開日2013-10-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Chemical Aspects of Resistance to the Antibiotic Fosfomycin Conferred by FosB from Bacillus cereus.
Biochemistry, 52, 2013
4O2I
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BU of 4o2i by Molmil
The crystal structure of non-LEE encoded type III effector C from Citrobacter rodentium
分子名称: Non-LEE encoded type III effector C, ZINC ION
著者Chang, C, Xu, X, Cui, H, Savchenko, A, Adkins, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP)
登録日2013-12-17
公開日2014-01-15
最終更新日2014-05-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of non-LEE encoded type III effector C from Citrobacter rodentium
To be Published
3FQC
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BU of 3fqc by Molmil
Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3,4,5-trimethoxyphenyl)pent-1-ynyl]-6-methylpyrimidine (UCP115A)
分子名称: 6-methyl-5-[3-methyl-3-(3,4,5-trimethoxyphenyl)but-1-yn-1-yl]pyrimidine-2,4-diamine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Trimethoprim-sensitive dihydrofolate reductase
著者Anderson, A.C, Frey, K.M, Liu, J, Lombardo, M.N.
登録日2009-01-07
公開日2009-03-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of wild-type and mutant methicillin-resistant Staphylococcus aureus dihydrofolate reductase reveal an alternate conformation of NADPH that may be linked to trimethoprim resistance.
J.Mol.Biol., 387, 2009
4JHI
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BU of 4jhi by Molmil
Crystal Structure of Medicago truncatula Nodulin 13 (MtN13) in complex with N6-benzyladenine
分子名称: MtN13 protein, N-BENZYL-9H-PURIN-6-AMINE, SODIUM ION
著者Ruszkowski, M, Sikorski, M, Jaskolski, M.
登録日2013-03-05
公開日2013-12-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The landscape of cytokinin binding by a plant nodulin.
Acta Crystallogr.,Sect.D, 69, 2013
3OP5
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BU of 3op5 by Molmil
Human vaccinia-related kinase 1
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Serine/threonine-protein kinase VRK1, ...
著者Allerston, C.K, Uttarkar, S, Savitsky, P, Elkins, J.M, Filippakopoulos, P, Krojer, T, Rellos, P, Fedorov, O, Eswaran, J, Brenner, B, Keates, T, Das, S, King, O, Chalk, R, Berridge, G, von Delft, F, Gileadi, O, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2010-08-31
公開日2010-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations.
Sci Rep, 7, 2017
4JHS
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BU of 4jhs by Molmil
Crystal structure of a C-terminal two domain fragment of human beta-2-glycoprotein 1
分子名称: Beta-2-glycoprotein 1, SULFATE ION
著者Bonanno, J.B, Toro, R, Gizzi, A, Chan, M.K, Garrett-Thomson, S.C, Patel, H, Lim, S, Matikainen, B, Celikgil, A, Garforth, S, Hillerich, B, Seidel, R, Rand, J.H, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
登録日2013-03-05
公開日2013-04-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a C-terminal two domain fragment of human beta-2-glycoprotein 1
To be Published
3FQN
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BU of 3fqn by Molmil
Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes
分子名称: Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ...
著者Petersen, J, Rossjohn, J.
登録日2009-01-07
公開日2009-03-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes
Proc.Natl.Acad.Sci.Usa, 106, 2009
4O3Z
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BU of 4o3z by Molmil
Crystal structure of the vaccine antigen Transferrin Binding Protein B (TbpB) mutant Tyr-95-Ala from Actinobacillus pleuropneumoniae H87
分子名称: ACETATE ION, GLYCEROL, Outer membrane protein; transferrin-binding protein
著者Calmettes, C, Yu, R.H, Schryvers, A.B, Moraes, T.F.
登録日2013-12-18
公開日2015-01-14
最終更新日2015-03-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Nonbinding site-directed mutants of transferrin binding protein B exhibit enhanced immunogenicity and protective capabilities.
Infect.Immun., 83, 2015
4NX8
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Structure of a PTP-like phytase from Bdellovibrio bacteriovorus
分子名称: GLYCEROL, MAGNESIUM ION, Protein-tyrosine phosphatase 2
著者Gruninger, R.J, Lovering, A.L.
登録日2013-12-08
公開日2014-07-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Structural and biochemical analysis of a unique phosphatase from Bdellovibrio bacteriovorus reveals its structural and functional relationship with the protein tyrosine phosphatase class of phytase.
Plos One, 9, 2014
4O4G
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Crystal Structure of HIV-1 Reverse Transcriptase in complex with 4-((4-(mesitylamino)-1,3,5-triazin-2-yl)amino)benzonitrile (JLJ527), a non-nucleoside inhibitor
分子名称: 4-({4-[(2,4,6-trimethylphenyl)amino]-1,3,5-triazin-2-yl}amino)benzonitrile, HIV-1 reverse transcriptase, p51 subunit, ...
著者Mislak, A.C, Frey, K.M.
登録日2013-12-18
公開日2014-11-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.712 Å)
主引用文献A mechanistic and structural investigation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase.
Biochim.Biophys.Acta, 1840, 2014
4JC8
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Crystal Structure of HOPS component Vps33 from Chaetomium thermophilum
分子名称: HOPS component Vps33
著者Baker, R.W, Jeffrey, P.D, Hughson, F.M.
登録日2013-02-21
公開日2013-05-08
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*
Plos One, 8, 2013
4JI6
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BU of 4ji6 by Molmil
Crystal Structure of 30S ribosomal subunit from Thermus thermophilus
分子名称: 16S rRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN S10, ...
著者Demirci, H, Wang, L, Murphy IV, F, Murphy, E, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T.
登録日2013-03-05
公開日2013-11-06
最終更新日2013-12-04
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献The central role of protein S12 in organizing the structure of the decoding site of the ribosome.
Rna, 19, 2013
4NDH
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Human Aprataxin (Aptx) bound to DNA, AMP, and Zn - product complex
分子名称: 5'-D(P*GP*TP*TP*CP*TP*AP*GP*AP*AP*C)-3', ADENOSINE MONOPHOSPHATE, Aprataxin, ...
著者Schellenberg, M.J, Tumbale, P.S, Williams, R.S.
登録日2013-10-26
公開日2013-12-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.848 Å)
主引用文献Aprataxin resolves adenylated RNA-DNA junctions to maintain genome integrity.
Nature, 506, 2013
4JEH
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Crystal Structure of Munc18a and Syntaxin1 lacking N-peptide complex
分子名称: Syntaxin-1A, Syntaxin-binding protein 1
著者Colbert, K.N, Hattendorf, D.A, Weiss, T.M, Burkhardt, P, Fasshauer, D, Weis, W.I.
登録日2013-02-27
公開日2013-07-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Syntaxin1a variants lacking an N-peptide or bearing the LE mutation bind to Munc18a in a closed conformation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JF3
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Crystal structure of the mpmv tm retroviral fusion core
分子名称: CHLORIDE ION, Envelope glycoprotein
著者Cook, J.D, Aydin, H, Lee, J.E.
登録日2013-02-27
公開日2013-10-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of Beta- and gammaretrovirus fusion proteins reveal a role for electrostatic stapling in viral entry.
J.Virol., 88, 2014
3FUT
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Apo-form of T. thermophilus 16S rRNA A1518 and A1519 methyltransferase (KsgA) in space group P21212
分子名称: Dimethyladenosine transferase
著者Demirci, H, Belardinelli, R, Seri, E, Gregory, S.T, Gualerzi, C, Dahlberg, A.E, Jogl, G.
登録日2009-01-14
公開日2009-03-31
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Structural rearrangements in the active site of the Thermus thermophilus 16S rRNA methyltransferase KsgA in a binary complex with 5'-methylthioadenosine.
J.Mol.Biol., 388, 2009
3OU9
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Crystal structure of gamma-carbonic anhydrase W19F mutant from Methanosarcina thermophila
分子名称: BICARBONATE ION, Carbonic anhydrase, ZINC ION
著者Domsic, J.F, Robbins, A.H, McKenna, R.
登録日2010-09-14
公開日2011-10-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of gamma-carbonic anhydrase W19F mutant from Methanosarcina thermophila
TO BE PUBLISHED

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件を2024-07-17に公開中

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