3OXF

Human lysine methyltransferase Smyd3 in complex with AdoHcy (Form I)

Summary for 3OXF

• Entry DOI: 10.2210/pdb3oxf/pdb
• Related: 3OXG
• Descriptor: SET and MYND domain-containing protein 3, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... (4 entities in total)
• Functional Keywords: smyd proteins, mynd, set domain, histone lysine methyltransferase, histone methylation, h3k4, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : Q9H7B4
• Total number of polymer chains: 2
• Total formula weight: 101659.80

Authors

Xu, S.,Wu, J.,Sun, B.,Zhong, C.,Ding, J. (deposition date: 2010-09-21, release date: 2011-02-23, Last modification date: 2023-11-01)

• Primary citation: Xu, S.,Wu, J.,Sun, B.,Zhong, C.,Ding, J.; Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding.; Nucleic Acids Res., 39:4438-4449, 2011; PubMed: 21266482; DOI: 10.1093/nar/gkr019

Experimental method

X-RAY DIFFRACTION (2.82 Å)