3OXF

Human lysine methyltransferase Smyd3 in complex with AdoHcy (Form I)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	SET and MYND domain-containing protein 3	polymer	436	50249.3	2	UniProt (Q9H7B4) Pfam (PF00856) Pfam (PF01753) In PDB	Homo sapiens (human)	Zinc finger MYND domain-containing protein 1
2	A, B	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
3	A, B	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
4		water	water		18.0	24	Chemie (HOH)

Sequence modifications

A, B: 1 - 428 (UniProt: Q9H7B4)

PDB	External Database	Details
Asn 13	Lys 13	SEE REMARK 999
Arg 140	Lys 140	SEE REMARK 999
Leu 429	-	expression tag
Glu 430	-	expression tag
His 431	-	expression tag
His 432	-	expression tag
His 433	-	expression tag
His 434	-	expression tag
His 435	-	expression tag
His 436	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	100498.5
Non-Polymers*	Number of molecules	8
	Total formula weight	1161.3
All*	Total formula weight	101659.8

*Water molecules are not included.