PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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5ZE2	Hairpin Complex, RAG1/2-hairpin 12RSS/23RSS complex in 5mM Mn2+ for 2 min at 4'C 分子名称: 1,2-ETHANEDIOL, DNA (30-MER), DNA (31-MER), ... 著者 Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. 登録日 2018-02-25 公開日 2018-04-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
6FY4	Structure of human NAD(P) H:quinone oxidoreductase in complex with N-(2-bromophenyl)pyrrolidine-1-sulfonamide 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N-(2-bromophenyl)pyrrolidine-1-sulfonamide, NAD(P)H dehydrogenase [quinone] 1 著者 Gruber, K, Hromic, A. 登録日 2018-03-10 公開日 2019-03-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 A small molecule chaperone rescues the stability and activity of a cancer-associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro. Febs Lett., 594, 2020
5WAD	ADC-7 in complex with boronic acid transition state inhibitor CR161 分子名称: Beta-lactamase, PHOSPHATE ION, phosphonooxy-[[[6-(1~{H}-1,2,3,4-tetrazol-5-yl)pyridin-3-yl]sulfonylamino]methyl]borinic acid 著者 Powers, R.A, Wallar, B.J. 登録日 2017-06-26 公開日 2017-12-06 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C beta-Lactamase. ACS Infect Dis, 4, 2018
5WET	Crystal Structure of H2-Dd with disulfide-linked 6mer peptide 分子名称: Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ... 著者 Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. 登録日 2017-07-10 公開日 2017-10-18 最終更新日 2017-12-13 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358, 2017
5WEU	Crystal Structure of H2-Dd with disulfide-linked 10mer peptide 分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, Envelope glycoprotein gp160, ... 著者 Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. 登録日 2017-07-10 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.584 Å) 主引用文献 Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358, 2017
5WFX	Structural basis for the interaction of 14-3-3beta with Tricarboxylic Acid Cycle intermediate Malate 分子名称: 14-3-3 protein beta/alpha 著者 Hou, Z.Q. 登録日 2017-07-12 公開日 2018-05-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.651 Å) 主引用文献 Structural basis for the interaction of 14-3-3 beta withTricarboxylic Acid Cycle intermediate Malate To Be Published
6B3E	Crystal structure of human CDK12/CyclinK in complex with an inhibitor 分子名称: 1,2-ETHANEDIOL, 2-[(2S)-1-(6-{[(4,5-difluoro-1H-benzimidazol-2-yl)methyl]amino}-9-ethyl-9H-purin-2-yl)piperidin-2-yl]ethan-1-ol, Cyclin-K, ... 著者 Ferguson, A.D. 登録日 2017-09-21 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Structure-Based Design of Selective Noncovalent CDK12 Inhibitors. ChemMedChem, 13, 2018
6GKO	Mouse thymidylate synthase cocrystallized with dUMP and soaked in phenolphthalein 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, DIMETHYL SULFOXIDE, ... 著者 Maj, P, Wilk, P, Jarmula, A, Weiss, M.S, Rode, W. 登録日 2018-05-21 公開日 2019-06-05 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.839 Å) 主引用文献 Thymidylate synthase fragment screening To Be Published
4DNY	Crystal structure of enterohemorrhagic E. coli StcE(132-251) 分子名称: IODIDE ION, Metalloprotease stcE 著者 Yu, A.C.Y, Strynadka, N.C.J. 登録日 2012-02-09 公開日 2012-05-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Structural Insight into the Bacterial Mucinase StcE Essential to Adhesion and Immune Evasion during Enterohemorrhagic E. coli Infection. Structure, 20, 2012
6GFA	Structure of Nucleotide binding domain of HSP110, ATP and Mg2+ complexed 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 105 kDa, MAGNESIUM ION 著者 Gonzalez, D, Gotthard, G, Gozzi, G.J, Seigneuric, R, Neiers, F, Briand, L, Garrido, C. 登録日 2018-04-29 公開日 2019-05-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Selecting the first chemical molecule inhibitor of HSP110 for colorectal cancer therapy. Cell Death Differ., 27, 2020
5WPM	KRas G12V, bound to GppNHp and miniprotein 225-11(A30R) 分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Lee, S.-J, Shim, S.Y, McGee, J.H, Verdine, G.L. 登録日 2017-08-05 公開日 2018-01-03 最終更新日 2018-03-14 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Exceptionally high-affinity Ras binders that remodel its effector domain. J. Biol. Chem., 293, 2018
5WGB	Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and E. coli ACP1 protein at 2.75A 分子名称: Acyl carrier protein, Cysteine desulfurase, mitochondrial, ... 著者 Boniecki, M.T, Cygler, M. 登録日 2017-07-13 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex. Nat Commun, 8, 2017
6BAB	The structure of human CamKII with bound inhibitor 分子名称: Calcium/calmodulin-dependent protein kinase type II subunit delta, L(+)-TARTARIC ACID, N-[(2S)-2-(diethylamino)propyl]-2-(3-hydroxyazetidin-1-yl)-6-[5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-3-yl]pyridine-4-carboxamide 著者 Somoza, J.R, Villasenor, A.G. 登録日 2017-10-12 公開日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 TBD To Be Published
5WSV	Crystal structure of Myosin VIIa IQ5 in complex with Ca2+-CaM 分子名称: CALCIUM ION, Calmodulin, SULFATE ION, ... 著者 Li, J, Chen, Y, Deng, Y, Lu, Q, Zhang, M. 登録日 2016-12-08 公開日 2017-06-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Ca(2+)-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single alpha Helix Lever Arm Extension Structure, 25, 2017
5WJ4	Crystal structure of redox-sensitive green fluorescent protein Clover mutant roClover1 分子名称: Green fluorescent protein 著者 Liu, C, Campbell, B.C, Petsko, G.A. 登録日 2017-07-21 公開日 2018-01-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.631 Å) 主引用文献 Crystal Structure of Green Fluorescent Protein Clover and Design of Clover-Based Redox Sensors. Structure, 26, 2018
6ANY	Structure of BmVAL-1 分子名称: Bm4233, isoform b, SULFATE ION, ... 著者 Asojo, O.A. 登録日 2017-08-14 公開日 2018-03-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of Brugia malayi venom allergen-like protein-1 (BmVAL-1), a vaccine candidate for lymphatic filariasis. Int. J. Parasitol., 48, 2018
2OKJ	The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67) 分子名称: 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase 1 著者 Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C. 登録日 2007-01-17 公開日 2007-03-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Nat.Struct.Mol.Biol., 14, 2007
5WJ2	Crystal structure of the green fluorescent protein Clover 分子名称: Green fluorescent protein 著者 Liu, C, Campbell, B.C, Petsko, G.A. 登録日 2017-07-21 公開日 2018-01-17 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.409 Å) 主引用文献 Crystal Structure of Green Fluorescent Protein Clover and Design of Clover-Based Redox Sensors. Structure, 26, 2018
6DAB	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6DAL	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, GLYCEROL, Nalpha-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl}-N-[2-(pyridin-3-yl)ethyl]-D-phenylalaninamide, ... 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
5ZE1	Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in 2mM Mn2+ for 10 min at 4'C 分子名称: 1,2-ETHANEDIOL, DNA, HMGB1 A-B box, ... 著者 Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. 登録日 2018-02-25 公開日 2018-04-25 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
6GTB	17beta-hydroxysteroid dehydrogenase 14 variant T205 in complex with FB211 分子名称: 1,2-ETHANEDIOL, 17-beta-hydroxysteroid dehydrogenase 14, 3-[6-(3-hydroxyphenyl)pyridin-2-yl]benzoic acid, ... 著者 Bertoletti, N, Marchais-Oberwinkler, S, Heine, A, Klebe, G. 登録日 2018-06-18 公開日 2019-09-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.619 Å) 主引用文献 X-ray Crystallographic Fragment screening and Hit Optimization To Be Published
5CQ5	Crystal structure of the bromodomain of bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) in complex with 2,3-Ethylenedioxybenzoic Acid (SGC - Diamond I04-1 fragment screening) 分子名称: 1,2-ETHANEDIOL, 2,3-dihydro-1,4-benzodioxine-5-carboxylic acid, Bromodomain adjacent to zinc finger domain protein 2B 著者 Bradley, A, Pearce, N, Krojer, T, Ng, J, Talon, R, Vollmar, M, Jose, B, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2015-07-21 公開日 2015-09-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.961 Å) 主引用文献 Crystal structure of the second bromodomain of bromodomain adjancent to zinc finger domain protein 2B (BAZ2B) in complex with 2,3-Ethylenedioxybenzoic Acid (SGC - Diamond I04-1 fragment screening) To be published
6DFP	Crystal Structure of a Tripartite Toxin Component VCA0883 from Vibrio cholerae 分子名称: VCA0883 著者 Kim, Y, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2018-05-15 公開日 2018-05-23 最終更新日 2022-07-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins. J.Bacteriol., 204, 2022
6GX5	Narrow Pick Filament from Pick's disease brain 分子名称: Microtubule-associated protein tau 著者 Falcon, B, Zhang, W, Murzin, A.G, Murshudov, G, Garringer, H.J, Vidal, R, Crowther, R.A, Ghetti, B, Scheres, S.H.W, Goedert, M. 登録日 2018-06-26 公開日 2018-09-12 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structures of filaments from Pick's disease reveal a novel tau protein fold. Nature, 561, 2018

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