PDB: 19228 件ウェブページステータス検索Chemie searchBIRD

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2JDS	Structure of cAMP-dependent protein kinase complexed with A-443654 分子名称: (2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE, CAMP-DEPENDENT PROTEIN KINASE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA 著者 Davies, T.G, Verdonk, M.L, Graham, B, Saalau-Bethell, S, Hamlett, C.C.F, McHardy, T, Collins, I, Garrett, M.D, Workman, P, Woodhead, S.J, Jhoti, H, Barford, D. 登録日 2007-01-12 公開日 2007-02-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A Structural Comparison of Inhibitor Binding to Pkb, Pka and Pka-Pkb Chimera J.Mol.Biol., 367, 2007
2JKK	Focal Adhesion Kinase catalytic domain in complex with bis-anilino pyrimidine inhibitor 分子名称: 2-({5-CHLORO-2-[(2-METHOXY-4-MORPHOLIN-4-YLPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)-N-METHYLBENZAMIDE, FOCAL ADHESION KINASE 1, SULFATE ION 著者 Lietha, D, Eck, M.J. 登録日 2008-08-28 公開日 2008-09-09 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of the Fak Kinase in Complex with Tae226 and Related Bis-Anilino Pyrimidine Inhibitors Reveal a Helical Dfg Conformation. Plos One, 3, 2008
2GNF	Protein kinase A fivefold mutant model of Rho-kinase with Y-27632 分子名称: (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, ... 著者 Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. 登録日 2006-04-10 公開日 2006-05-23 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity J.Biol.Chem., 281, 2006
2GP5	Crystal structure of catalytic core domain of jmjd2A complexed with alpha-Ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, Jumonji domain-containing protein 2A, ... 著者 Chen, Z, Zang, J, Whetstine, J, Hong, X, Davrazou, F, Kutateladze, T.G, Simpson, M, Dai, S, Hagman, J, Shi, Y, Zhang, G. 登録日 2006-04-16 公開日 2006-05-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structural insights into histone demethylation by JMJD2 family members Cell(Cambridge,Mass.), 125, 2006
2GNG	Protein kinase A fivefold mutant model of Rho-kinase 分子名称: cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, alpha-catalytic subunit 著者 Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. 登録日 2006-04-10 公開日 2006-05-23 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity J.Biol.Chem., 281, 2006
2H6F	Protein Farnesyltransferase Complexed with a Farnesylated DDPTASACVLS Peptide Product at 1.5A Resolution 分子名称: ACETIC ACID, FARNESYL, Protein farnesyltransferase beta subunit, ... 著者 Terry, K.L, Beese, L.S. 登録日 2006-05-31 公開日 2006-08-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Conversion of protein farnesyltransferase to a geranylgeranyltransferase. Biochemistry, 45, 2006
2H6G	W102T Protein Farnesyltransferase Mutant Complexed with a Geranylgeranylated DDPTASACVLS Peptide Product at 1.85A Resolution 分子名称: GERAN-8-YL GERAN, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ... 著者 Terry, K.L, Beese, L.S. 登録日 2006-05-31 公開日 2006-08-29 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Conversion of protein farnesyltransferase to a geranylgeranyltransferase. Biochemistry, 45, 2006
4HI4	Crystal structure of the 5-coordinate ferric heme-binding PAS domain of Aer2 from P. aeruginosa 分子名称: Aerotaxis transducer Aer2, CHLORIDE ION, GLYCEROL, ... 著者 Airola, M.V, Crane, B.R. 登録日 2012-10-11 公開日 2013-01-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling. J.Mol.Biol., 425, 2013
2HA3	Crystal structure of mouse acetylcholinesterase complexed with choline 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, CHOLINE ION, ... 著者 Bourne, Y, Radic, Z, Sulzenbacher, G, Kim, E, Taylor, P, Marchot, P. 登録日 2006-06-12 公開日 2006-07-18 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding J.Biol.Chem., 281, 2006
2GNK	GLNK, A SIGNAL PROTEIN FROM E. COLI 分子名称: ADENOSINE-5'-TRIPHOSPHATE, PROTEIN (NITROGEN REGULATORY PROTEIN) 著者 Xu, Y, Cheah, E, Carr, P.D, van Heeswijk, W.C, Westerhoff, H.V, Vasudevan, S.G, Ollis, D.L. 登録日 1998-07-14 公開日 1999-07-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 GlnK, a PII-homologue: structure reveals ATP binding site and indicates how the T-loops may be involved in molecular recognition. J.Mol.Biol., 282, 1998
2GNI	PKA fivefold mutant model of Rho-kinase with inhibitor Fasudil (HA1077) 分子名称: 5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, ... 著者 Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. 登録日 2006-04-10 公開日 2006-05-23 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity J.Biol.Chem., 281, 2006
4IAK	Low temperature X-ray structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBONATE ION, STRONTIUM ION, ... 著者 Gerlits, O, Kovalevsky, A. 登録日 2012-12-06 公開日 2013-06-12 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
4IAY	Room temperature X-ray Structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, STRONTIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Gerlits, O, Kovalevsky, A. 登録日 2012-12-07 公開日 2013-06-12 最終更新日 2013-12-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
2GVL	Crystal Structure of Murine NMPRTase 分子名称: Nicotinamide phosphoribosyltransferase 著者 Khan, J.A, Tao, X, Tong, L. 登録日 2006-05-02 公開日 2006-07-25 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat.Struct.Mol.Biol., 13, 2006
2GRB	Crystal Structure of an RNA Quadruplex Containing Inosine-tetrad 分子名称: 5'-R(*(U33)P*GP*IP*GP*GP*U)-3', POTASSIUM ION, STRONTIUM ION 著者 Pan, B, Shi, K, Sundaralingam, M. 登録日 2006-04-24 公開日 2006-11-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of an RNA quadruplex containing inosine tetrad: implications for the roles of NH2 group in purine tetrads. J.Mol.Biol., 363, 2006
4IAF	Room temperature X-ray Structure OF cAMP dependent protein kinase A in complex with high Mg2+ concentration, ADP and phosphorylated peptide pSP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Gerlits, O, Kovalevsky, A. 登録日 2012-12-06 公開日 2013-06-12 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20. Biochemistry, 52, 2013
2H3B	Crystal Structure of Mouse Nicotinamide Phosphoribosyltransferase/Visfatin/Pre-B Cell Colony Enhancing Factor 1 分子名称: Nicotinamide phosphoribosyltransferase, SULFATE ION 著者 Wang, T, Zhang, X, Bheda, P, Revollo, J.R, Imai, S.I, Wolberger, C. 登録日 2006-05-22 公開日 2006-06-20 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of Nampt/PBEF/visfatin, a mammalian NAD(+) biosynthetic enzyme. Nat.Struct.Mol.Biol., 13, 2006
2HA0	Crystal structure of mouse acetylcholinesterase complexed with 4-ketoamyltrimethylammonium 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4-DIHYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM, Acetylcholinesterase, ... 著者 Bourne, Y, Radic, Z, Sulzenbacher, G, Kim, E, Taylor, P, Marchot, P. 登録日 2006-06-12 公開日 2006-07-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding J.Biol.Chem., 281, 2006
2JDT	Structure of PKA-PKB chimera complexed with ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY) ETHYLAMINO)ETHYL)AMIDE 分子名称: CAMP-DEPENDENT PROTEIN KINASE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE 著者 Davies, T.G, Verdonk, M.L, Graham, B, Saalau-Bethell, S, Hamlett, C.C.F, McHardy, T, Collins, I, Garrett, M.D, Workman, P, Woodhead, S.J, Jhoti, H, Barford, D. 登録日 2007-01-12 公開日 2007-02-13 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 A Structural Comparison of Inhibitor Binding to Pkb, Pka and Pka-Pkb Chimera J.Mol.Biol., 367, 2007
2JKM	Focal Adhesion Kinase catalytic domain in complex with bis-anilino pyrimidine inhibitor 分子名称: 2-{[5-CHLORO-2-({(1E,4R)-2-METHOXY-4-[(3R)-3-(METHYLAMINO)PYRROLIDIN-1-YL]CYCLOHEXA-2,5-DIEN-1-YLIDENE}AMINO)PYRIMIDIN-4-YL]AMINO}-N-(1-METHYLETHYL)BENZENESULFONAMIDE, FOCAL ADHESION KINASE 1 著者 Lietha, D, Eck, M.J. 登録日 2008-08-28 公開日 2008-09-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystal Structures of the Fak Kinase in Complex with Tae226 and Related Bis-Anilino Pyrimidine Inhibitors Reveal a Helical Dfg Conformation. Plos One, 3, 2008
2GNL	PKA threefold mutant model of Rho-kinase with inhibitor H-1152P 分子名称: (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE, cAMP-dependent protein kinase inhibitor alpha, cAMP-dependent protein kinase, ... 著者 Bonn, S, Herrero, S, Breitenlechner, C.B, Engh, R.A, Gassel, M, Bossemeyer, D. 登録日 2006-04-10 公開日 2006-05-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity J.Biol.Chem., 281, 2006
2GVJ	Crystal Structure of Human NMPRTase in complex with FK866 分子名称: (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide, Nicotinamide phosphoribosyltransferase 著者 Khan, J.A, Tao, X, Tong, L. 登録日 2006-05-02 公開日 2006-06-20 最終更新日 2016-11-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat.Struct.Mol.Biol., 13, 2006
2GYW	Crystal Structure of Mus musculus Acetylcholinesterase in Complex with Obidoxime 分子名称: 1,1'-(OXYDIMETHYLENE)BIS(4-FORMYLPYRIDINIUM)DIOXIME, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... 著者 Pang, Y.P, Boman, M, Artursson, E, Akfur, C, Lundberg, S. 登録日 2006-05-10 公開日 2006-08-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: Structural basis for differences in the ability to reactivate tabun conjugates. Biochem.Pharm., 72, 2006
2GYU	Crystal structure of Mus musculus Acetylcholinesterase in complex with HI-6 分子名称: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(AMINOCARBONYL)-1-[({2-[(E)-(HYDROXYIMINO)METHYL]PYRIDINIUM-1-YL}METHOXY)METHYL]PYRIDINIUM, ... 著者 Pang, Y.P, Boman, M, Artursson, E, Akfur, C, Lundberg, S. 登録日 2006-05-10 公開日 2006-08-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: Structural basis for differences in the ability to reactivate tabun conjugates. Biochem.Pharm., 72, 2006
4IB1	Structure of cAMP dependent protein kinase A in complex with high K+ concentration, ADP and phosphorylated peptide pSP20 分子名称: ADENOSINE-5'-DIPHOSPHATE, POTASSIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Gerlits, O, Kovalevsky, A. 登録日 2012-12-07 公開日 2013-12-11 最終更新日 2014-05-28 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Metal-Free cAMP-Dependent Protein Kinase Can Catalyze Phosphoryl Transfer. Biochemistry, 53, 2014

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