8TBW
 
 | | Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) peptide KLSHQPVLL | | 分子名称: | Beta-2-microglobulin, HLA-A*02:01 alpha chain, NITRATE ION, ... | | 著者 | Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M. | | 登録日 | 2023-06-29 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.081 Å) | | 主引用文献 | Accurate modeling of peptide-MHC structures with AlphaFold.
Structure, 32, 2024
|
|
4U1K
 | | HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | | 著者 | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | | 登録日 | 2014-07-15 | | 公開日 | 2015-04-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
|
|
7ZT5
 | |
7N5P
 | | 6218 TCR in complex with H2-Db PA224-233 with a cysteine mutant | | 分子名称: | Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ... | | 著者 | Szeto, C, Gras, S. | | 登録日 | 2021-06-06 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
Nat Commun, 13, 2022
|
|
7YXB
 | | MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange | | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, CLIP peptide, ... | | 著者 | Roske, Y, Abualrous, E.T, Freund, C. | | 登録日 | 2022-02-15 | | 公開日 | 2023-02-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | | 主引用文献 | MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
Nat.Chem.Biol., 19, 2023
|
|
7WT5
 | | Crystal structure of HLA-A*2450 complexed with 8-mer model peptide | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 8-mer model peptide, ... | | 著者 | Asa, M, Morita, D, Sugita, M. | | 登録日 | 2022-02-03 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.0950768 Å) | | 主引用文献 | Crystal structures of N-myristoylated lipopeptide-bound HLA class I complexes indicate reorganization of B-pocket architecture upon ligand binding.
J.Biol.Chem., 298, 2022
|
|
2R0Z
 | |
3QQ4
 | | Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides | | 分子名称: | Beta-2-microglobulin, MHC class I antigen, VP35 | | 著者 | Zhang, N, Qi, J, Gao, F, Pan, X, Chen, R, Li, Q, Chen, Z, Li, X, Xia, C, Gao, G.F. | | 登録日 | 2011-02-15 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | | 主引用文献 | Crystal structure of swine major histocompatibility complex class I SLA-1 0401 and identification of 2009 pandemic swine-origin influenza A H1N1 virus cytotoxic T lymphocyte epitope peptides.
J.Virol., 85, 2011
|
|
4ZDH
 | | Crystal structure of JKA6 TCR | | 分子名称: | Alpha chain of A6 T-cell receptor,T-cell receptor alpha chain C region, Beta chain of JKF6 T-cell receptor,Protein TRBV28 | | 著者 | Singh, N.K, Hossain, M, Baker, B.M. | | 登録日 | 2015-04-17 | | 公開日 | 2016-05-04 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.0984 Å) | | 主引用文献 | Crystal structure of JKA6 TCR
To Be Published
|
|
7R7X
 | | Crystal structure of HLA-B*5701 complex with an HIV-1 Gag-derived epitope QW9 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, GLN-ALA-SER-GLN-GLU-VAL-LYS-ASN-TRP, ... | | 著者 | Li, X.L, Tan, K.M, Walker, B.D, Wang, J.H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-06-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Molecular basis of differential HLA class I-restricted T cell recognition of a highly networked HIV peptide.
Nat Commun, 14, 2023
|
|
5D2N
 | | Crystal structure of C25-NLV-HLA-A2 complex | | 分子名称: | ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, C25 alpha, ... | | 著者 | Mariuzza, R.A, Yang, X. | | 登録日 | 2015-08-05 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.
J.Biol.Chem., 290, 2015
|
|
1MH5
 | | The Structure Of The Complex Of The Fab Fragment Of The Esterolytic Antibody MS6-164 and A Transition-State Analog | | 分子名称: | IMMUNOGLOBULIN MS6-164, N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE, SULFATE ION | | 著者 | Ruzheinikov, S.N, Muranova, T.A, Sedelnikova, S.E, Partridge, L.J, Blackburn, G.M, Murray, I.A, Kakinuma, H, Takashi, N, Shimazaki, K, Sun, J, Nishi, Y, Rice, D.W. | | 登録日 | 2002-08-19 | | 公開日 | 2003-09-23 | | 最終更新日 | 2011-11-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
J.Mol.Biol., 332, 2003
|
|
2AJY
 | |
4G8F
 | | Crystal Structure of clone42 TCR | | 分子名称: | alpha chain clone 42 TCR, beta chain clone 42 TCR | | 著者 | Gras, S, Bhati, M, Rossjohn, J. | | 登録日 | 2012-07-23 | | 公開日 | 2013-05-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A conserved human T cell population targets mycobacterial antigens presented by CD1b.
Nat.Immunol., 14, 2013
|
|
3MV8
 | | Crystal Structure of the TK3-Gln55His TCR in complex with HLA-B*3501/HPVG | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | | 著者 | Gras, S, Chen, Z, Miles, J.J, Liu, Y.C, Bell, M.J, Sullivan, L.C, Kjer-Nielsen, L, Brennan, R.M, Burrows, J.M, Neller, M.A, Khanna, R, Purcell, A.W, Brooks, A.G, McCluskey, J, Rossjohn, J, Burrows, S.R. | | 登録日 | 2010-05-03 | | 公開日 | 2010-06-09 | | 最終更新日 | 2011-07-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Allelic polymorphism in the T cell receptor and its impact on immune responses
J.Exp.Med., 207, 2010
|
|
5WLG
 | | Crystal Structure of H-2Db with the GAP501 peptide (SQL) | | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GAP50 peptide, ... | | 著者 | Gras, S, Farenc, C, Josephs, T, Rossjohn, J. | | 登録日 | 2017-07-26 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene.
Immunity, 47, 2017
|
|
2D4D
 | | The Crystal Structure of human beta2-microglobulin, L39W W60F W95F Mutant | | 分子名称: | Beta-2-microglobulin, SODIUM ION | | 著者 | Iwata, K, Matsuura, T, Nakagawa, A, Goto, Y. | | 登録日 | 2005-10-17 | | 公開日 | 2006-08-08 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis
J.Biol.Chem., 281, 2006
|
|
4OGY
 | | Crystal structure of Fab DX-2930 in complex with human plasma kallikrein at 2.1 Angstrom resolution | | 分子名称: | 1,2-ETHANEDIOL, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN, ... | | 著者 | Edwards, T.E, Clifton, M.C, Abendroth, J, Nixon, A, Ladner, R. | | 登録日 | 2014-01-16 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Inhibition of plasma kallikrein by a highly specific active site blocking antibody.
J.Biol.Chem., 289, 2014
|
|
2RCS
 | | IMMUNOGLOBULIN 48G7 GERMLINE FAB-AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY | | 分子名称: | IMMUNOGLOBULIN 48G7 GERMLINE FAB | | 著者 | Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C. | | 登録日 | 1997-05-14 | | 公開日 | 1997-11-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
|
|
8HSO
 | |
3RWG
 | | Rhesus macaque MHC class I molecule Mamu-B*17-MW9 | | 分子名称: | 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Wu, Y, Gao, F, Liu, J, Qi, J.X, Price, D.A, Gao, G.F. | | 登録日 | 2011-05-09 | | 公開日 | 2012-03-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of diverse peptide accommodation by the rhesus macaque MHC class I molecule Mamu-B*17: insights into immune protection from simian immunodeficiency virus
J.Immunol., 187, 2011
|
|
6UGX
 | | Crystal structure of the Fc fragment of PF06438179/GP1111 an infliximab biosimilar in a primative orthorhombic crystal form, Lot A | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Mayclin, S.J, Edwards, T.E. | | 登録日 | 2019-09-26 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar.
BioDrugs, 34, 2020
|
|
3MRI
 | | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide G4M-V5W variant | | 分子名称: | 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Reiser, J.-B, Le Gorrec, M, Chouquet, A, Debeaupuis, E, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | | 登録日 | 2010-04-29 | | 公開日 | 2011-05-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide G4M-V5W variant
To be Published
|
|
4UQ3
 | | Crystal structure of HLA-A0201 in complex with an azobenzene- containing peptide | | 分子名称: | AZOBENZENE-CONTAINING PEPTIDE, BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Thong, S.Y, Yap, J.W, Lim, P.Y, Verhelst, S.H, Lescar, J, Meijers, R, Grotenbreg, G.M. | | 登録日 | 2014-06-19 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides.
Angew. Chem. Int. Ed. Engl., 53, 2014
|
|
3E6H
 | | MHC CLASS I H-2Dd heavy chain complexed with Beta-2 Microglobulin and a variant peptide, PI10, from the human immunodeficiency virus (BaL) envelope glycoprotein 120 | | 分子名称: | Envelope glycoprotein 10-residue peptide, H-2 class I histocompatibility antigen, D-D alpha chain, ... | | 著者 | Wang, R, Natarajan, K, Robinson, H, Margulies, D.H. | | 登録日 | 2008-08-15 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity
J.Immunol., 183, 2009
|
|
