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1U7O
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Magnesium Dependent Phosphatase 1 (MDP-1)
分子名称: ACETATE ION, magnesium-dependent phosphatase-1
著者Peisach, E, Selengut, J.D, Dunaway-Mariano, D, Allen, K.N.
登録日2004-08-04
公開日2004-10-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray crystal structure of the hypothetical phosphotyrosine phosphatase MDP-1 of the haloacid dehalogenase superfamily
Biochemistry, 43, 2004
3RT1
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Maltodextarn bound activated state form of yeast glycogen synthase isoform 2
分子名称: 6-O-phosphono-alpha-D-glucopyranose, DI(HYDROXYETHYL)ETHER, PROTEIN (Glycogen [starch] synthase isoform 2), ...
著者Baskaran, S, Hurley, T.D.
登録日2011-05-02
公開日2011-08-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen.
J.Biol.Chem., 286, 2011
3N5F
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Crystal Structure of L-N-carbamoylase from Geobacillus stearothermophilus CECT43
分子名称: CACODYLATE ION, COBALT (II) ION, ISOPROPYL ALCOHOL, ...
著者Garcia-Pino, A, Martinez-Rodriguez, S, Gavira, J.A.
登録日2010-05-25
公開日2011-05-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Mutational and structural analysis of L-N-carbamoylase reveals new insights into a peptidase m20/m25/m40 family member.
J.Bacteriol., 194, 2012
4XSS
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BU of 4xss by Molmil
Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ...
著者Lawrence, C, Kong, G.K.-W, Menting, J.G, Lawrence, M.C.
登録日2015-01-22
公開日2015-06-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors.
Structure, 23, 2015
5XVN
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BU of 5xvn by Molmil
E. far Cas1-Cas2/prespacer binary complex
分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ...
著者Xiao, Y, Ng, S, Nam, K.H, Ke, A.
登録日2017-06-28
公開日2017-10-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
Nature, 550, 2017
4Y5Y
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Diabody 330 complex with EpoR
分子名称: Erythropoietin receptor, GLYCEROL, diabody 330 VH domain, ...
著者Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
登録日2015-02-12
公開日2015-03-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
3N8I
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Crystal structure of the A isoform of human cytoplasmic protein tyrosine phosphatase (HCPTP-A) in complex with 1-naphtylacetic acid
分子名称: Low molecular weight phosphotyrosine protein phosphatase, NAPHTHALEN-1-YL-ACETIC ACID
著者Homan, K.T, Balasubramaniam, D, Stauffacher, C.V.
登録日2010-05-28
公開日2011-12-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Characterization of a Secondary Binding Site on Low Molecular Weight Protein Tyrosine Phosphatases
To be Published
3FAK
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Structural and Functional Analysis of a Hormone-Sensitive Lipase like EstE5 from a Metagenome Library
分子名称: CHLORIDE ION, Esterase/lipase, SODIUM ION
著者Hwang, K.Y, Nam, K.H.
登録日2008-11-17
公開日2009-02-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional analysis of a novel EstE5 belonging to the subfamily of hormone-sensitive lipase
Biochem.Biophys.Res.Commun., 379, 2009
1YIC
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BU of 1yic by Molmil
THE OXIDIZED SACCHAROMYCES CEREVISIAE ISO-1-CYTOCHROME C, NMR, 20 STRUCTURES
分子名称: CYTOCHROME C, ISO-1, HEME C
著者Banci, L, Bertini, I, Bren, K.L, Gray, H.B, Sompornpisut, P, Turano, P.
登録日1997-02-18
公開日1997-07-23
最終更新日2021-11-03
実験手法SOLUTION NMR
主引用文献Solution structure of oxidized Saccharomyces cerevisiae iso-1-cytochrome c.
Biochemistry, 36, 1997
4KC3
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BU of 4kc3 by Molmil
Cytokine/receptor binary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor-like 1, Interleukin-33
著者Liu, X, Wang, X.Q.
登録日2013-04-24
公開日2013-08-28
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.2702 Å)
主引用文献Structural insights into the interaction of IL-33 with its receptors.
Proc.Natl.Acad.Sci.USA, 110, 2013
3F1N
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Crystal structure of a high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains, with internally bound ethylene glycol.
分子名称: 1,2-ETHANEDIOL, Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1
著者Scheuermann, T.H, Tomchick, D.R, Machius, M, Guo, Y, Bruick, R.K, Gardner, K.H.
登録日2008-10-28
公開日2009-01-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.479 Å)
主引用文献Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Proc.Natl.Acad.Sci.USA, 106, 2009
1EE2
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BU of 1ee2 by Molmil
THE STRUCTURE OF STEROID-ACTIVE ALCOHOL DEHYDROGENASE AT 1.54 A RESOLUTION
分子名称: ALCOHOL DEHYDROGENASE, CHOLIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Adolph, H.W.
登録日2000-01-30
公開日2000-10-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural basis for substrate specificity differences of horse liver alcohol dehydrogenase isozymes.
Biochemistry, 39, 2000
3ICB
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BU of 3icb by Molmil
THE REFINED STRUCTURE OF VITAMIN D-DEPENDENT CALCIUM-BINDING PROTEIN FROM BOVINE INTESTINE. MOLECULAR DETAILS, ION BINDING, AND IMPLICATIONS FOR THE STRUCTURE OF OTHER CALCIUM-BINDING PROTEINS
分子名称: CALCIUM ION, CALCIUM-BINDING PROTEIN, SULFATE ION
著者Szebenyi, D.M.E, Moffat, K.
登録日1986-09-09
公開日1986-10-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The refined structure of vitamin D-dependent calcium-binding protein from bovine intestine. Molecular details, ion binding, and implications for the structure of other calcium-binding proteins.
J.Biol.Chem., 261, 1986
1PJL
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BU of 1pjl by Molmil
Crystal structure of human m-NAD-ME in ternary complex with NAD and Lu3+
分子名称: LUTETIUM (III) ION, NAD-dependent malic enzyme, mitochondrial, ...
著者Yang, Z, Batra, R, Floyd, D.L, Hung, H.-C, Chang, G.-G, Tong, L.
登録日2003-06-03
公開日2003-06-17
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Potent and competitive inhibition of malic enzymes by lanthanide ions
Biochem.Biophys.Res.Commun., 274, 2000
1QZC
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BU of 1qzc by Molmil
Coordinates of S12, SH44, LH69 and SRL separately fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S12
著者Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J.
登録日2003-09-16
公開日2003-11-04
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy
Nat.Struct.Biol., 10, 2003
1QZD
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EF-Tu.kirromycin coordinates fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome
分子名称: Elongation factor Tu
著者Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J.
登録日2003-09-16
公開日2003-11-04
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy
Nat.Struct.Biol., 10, 2003
7YMB
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BU of 7ymb by Molmil
Structure of Alcohol dehydrogenase from Candida glabrata(CgADH)complexed with NADPH
分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-dependent methylglyoxal reductase GRE2
著者Sun, Z.W, Liu, Y.F, Xu, G.C, Ni, Y.
登録日2022-07-28
公開日2023-08-02
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献rational desigen of CgADH from Candida glabrata for stereocomplementary reduction of azacyclone.
To Be Published
1HYN
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BU of 1hyn by Molmil
CRYSTAL STRUCTURE OF THE CYTOPLASMIC DOMAIN OF HUMAN ERYTHROCYTE BAND-3 PROTEIN
分子名称: BAND 3 ANION TRANSPORT PROTEIN
著者Zhang, D, Kiyatkin, A, Bolin, J.T, Low, P.S.
登録日2001-01-20
公開日2001-05-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystallographic structure and functional interpretation of the cytoplasmic domain of erythrocyte membrane band 3.
Blood, 96, 2000
1QZA
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BU of 1qza by Molmil
Coordinates of the A/T site tRNA model fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome
分子名称: Phe-tRNA
著者Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J.
登録日2003-09-16
公開日2003-11-04
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy
Nat.Struct.Biol., 10, 2003
2R4F
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BU of 2r4f by Molmil
Substituted Pyrazoles as Hepatselective HMG-COA reductase inhibitors
分子名称: (3R,5R)-7-[1-(4-fluorophenyl)-4-(1-methylethyl)-3-{methyl[(1R)-1-phenylethyl]carbamoyl}-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION
著者Pavlovsky, A, Pfefferkorn, J.A, Harris, M.S, Finzel, B.C.
登録日2007-08-31
公開日2008-04-29
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia.
J.Med.Chem., 51, 2008
8POM
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BU of 8pom by Molmil
TEAD2 in complex with an inhibitor
分子名称: 2-[[3-(2-phenylethoxy)phenyl]amino]pyridine-3-carboxylic acid, GLYCEROL, Transcriptional enhancer factor TEF-4
著者Guichou, J.F.
登録日2023-07-05
公開日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings.
Bioorg.Med.Chem.Lett., 95, 2023
7PTQ
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RNA origami 5-helix tile
分子名称: Chains: C
著者McRae, E.K.S, Andersen, E.S.
登録日2021-09-27
公開日2022-10-05
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.08 Å)
主引用文献Structure, folding and flexibility of co-transcriptional RNA origami.
Nat Nanotechnol, 18, 2023
8POJ
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TEAD2 in complex with an inhibitor
分子名称: 4-fluoranyl-2-[(3-phenylphenyl)amino]benzoic acid, MYRISTIC ACID, Transcriptional enhancer factor TEF-4
著者Guichou, J.F.
登録日2023-07-05
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings.
Bioorg.Med.Chem.Lett., 95, 2023
7PTS
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BU of 7pts by Molmil
RNA origami 5-helix tile
分子名称: 5HT-B
著者McRae, E.K.S, Andersen, E.S.
登録日2021-09-27
公開日2022-10-05
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (5.71 Å)
主引用文献Structure, folding and flexibility of co-transcriptional RNA origami.
Nat Nanotechnol, 18, 2023
7PTK
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Young conformer of a 6-helix bundle of RNA with clasp
分子名称: RNA
著者McRae, E.K.S, Andersen, E.S.
登録日2021-09-27
公開日2022-10-05
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (5.18 Å)
主引用文献Structure, folding and flexibility of co-transcriptional RNA origami.
Nat Nanotechnol, 18, 2023

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件を2024-08-07に公開中

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