PDB: 13488 件ウェブページステータス検索Chemie searchBIRD

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4QA3	Crystal structure of T311M HDAC8 in complex with Trichostatin A (TSA) 分子名称: GLYCEROL, Histone deacetylase 8, POTASSIUM ION, ... 著者 Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2014-05-02 公開日 2014-08-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.876 Å) 主引用文献 Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
4MD7	Crystal Structure of full-length symmetric CK2 holoenzyme 分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION 著者 Lolli, G, Ranchio, A, Battistutta, R. 登録日 2013-08-22 公開日 2013-11-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Active Form of the Protein Kinase CK2 alpha 2 beta 2 Holoenzyme Is a Strong Complex with Symmetric Architecture. Acs Chem.Biol., 9, 2014
4QO3	Crystal structure of C16S/N18S/K12V/C117V/P134V mutant of human acidic fibroblast growth factor 分子名称: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE 著者 Blaber, M, Xia, X. 登録日 2014-06-19 公開日 2015-05-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.047 Å) 主引用文献 Thermodynamics of Cysteine Substitution Suggest Unique Structural Role for Cysteine in Proteins To be Published
4QA7	Crystal structure of H334R/Y306F HDAC8 in complex with a tetrapeptide substrate 分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, GLYCEROL, Histone deacetylase 8, ... 著者 Decroos, C, Bowman, C.B, Moser, J.-A.S, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2014-05-02 公開日 2014-08-06 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Compromised Structure and Function of HDAC8 Mutants Identified in Cornelia de Lange Syndrome Spectrum Disorders. Acs Chem.Biol., 9, 2014
2G99	Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5 分子名称: Histone H3, WD-repeat protein 5 著者 Chai, J, Han, Z, Wang, H, Shen, Y. 登録日 2006-03-06 公開日 2006-09-06 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5 To be published
4QLI	A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation 分子名称: 14-3-3 protein sigma, GLYCEROL, MAGNESIUM ION, ... 著者 Bier, D, Ottmann, C. 登録日 2014-06-12 公開日 2015-06-17 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 A novel phospho-switch in the linker region of the snail zinc finger protein which regulates 14-3-3 association, DNA binding and epithelial-mesenchymal differentiation To be Published
4QS7	Arabidopsis Hexokinase 1 (AtHXK1) structure in glucose-bound form 分子名称: Hexokinase-1, beta-D-glucopyranose 著者 Feng, J, Zhao, S, Liu, L. 登録日 2014-07-03 公開日 2015-02-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Biochemical and structural study of Arabidopsis hexokinase 1 Acta Crystallogr.,Sect.D, 71, 2015
4QTR	Computational design of co-assembling protein-DNA nanowires 分子名称: DNA (5'-D(P*CP*GP*GP*AP*AP*AP*TP*TP*AP*AP*AP*TP*TP*AP*CP*A)-3'), DNA (5'-D(P*GP*TP*GP*TP*AP*AP*TP*TP*TP*AP*AP*TP*TP*TP*CP*C)-3'), dualENH 著者 Mou, Y, Mayo, S.L. 登録日 2014-07-08 公開日 2015-07-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Computational design of co-assembling protein-DNA nanowires. Nature, 525, 2015
4IA9	Crystal structure of human WD REPEAT DOMAIN 5 in complex with 2-chloro-4-fluoro-3-methyl-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide 分子名称: 1,2-ETHANEDIOL, 2-chloro-4-fluoro-3-methyl-N-[2-(4-methylpiperazin-1-yl)-5-nitrophenyl]benzamide, UNKNOWN ATOM OR ION, ... 著者 Dong, A, Dombrovski, L, Bolshan, Y, Getlik, M, Tempel, W, Kuznetsova, E, Wasney, G.A, Hajian, T, Poda, G, Nguyen, K.T, Schapira, M, Brown, P.J, Al-awar, R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Smil, D, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) 登録日 2012-12-06 公開日 2012-12-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Synthesis, Optimization, and Evaluation of Novel Small Molecules as Antagonists of WDR5-MLL Interaction. ACS Med Chem Lett, 4, 2013
4QQK	Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) with GMS 分子名称: (5S)-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}-N~6~-carbamimidoyl-L-lysine, GLYCEROL, Protein arginine N-methyltransferase 6, ... 著者 Dong, A, Zeng, H, He, H, Wernimont, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Luo, M, Wu, H, Structural Genomics Consortium (SGC) 登録日 2014-06-27 公開日 2014-07-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural basis of arginine asymmetrical dimethylation by PRMT6. Biochem. J., 473, 2016
4RAG	CRYSTAL STRUCTURE of PPC2A-D38K 分子名称: MANGANESE (II) ION, Protein phosphatase 1A 著者 Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. 登録日 2014-09-10 公開日 2015-08-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 The catalytic role of the M2 metal ion in PP2C alpha Sci Rep, 5, 2015
4QS9	Arabidopsis Hexokinase 1 (AtHXK1) mutant S177A structure in glucose-bound form 分子名称: Hexokinase-1, beta-D-glucopyranose 著者 Feng, J, Zhao, S, Liu, L. 登録日 2014-07-03 公開日 2015-02-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.103 Å) 主引用文献 Biochemical and structural study of Arabidopsis hexokinase 1 Acta Crystallogr.,Sect.D, 71, 2015
6ASY	BiP-ATP2 分子名称: 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, ... 著者 Liu, Q, Yang, J, Zong, Y, Columbus, L, Zhou, L. 登録日 2017-08-26 公開日 2017-12-06 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s. Nat Commun, 8, 2017
4RAF	Crystal structure of PP2Ca-D38A 分子名称: MANGANESE (II) ION, Protein phosphatase 1A 著者 Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. 登録日 2014-09-10 公開日 2015-08-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 The catalytic role of the M2 metal ion in PP2C alpha Sci Rep, 5, 2015
4RDU	Crystal structure of a distal-less homeobox protein 5 (Dlx5) from Homo sapiens at 1.85 A resolution 分子名称: (DC)(DG)(DA)(DC)(DT)(DA)(DA)(DT)(DT)(DA)(DG)(DT)(DC)(DG), Homeobox protein DLX-5 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2014-09-19 公開日 2014-11-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of a distal-less homeobox protein 5 (Dlx5) from Homo sapiens at 1.85 A resolution To be published
4QS8	Arabidopsis Hexokinase 1 (AtHXK1) structure in ligand-free form 分子名称: Hexokinase-1 著者 Feng, J, Zhao, S, Liu, L. 登録日 2014-07-03 公開日 2015-02-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.798 Å) 主引用文献 Biochemical and structural study of Arabidopsis hexokinase 1 Acta Crystallogr.,Sect.D, 71, 2015
4R0Z	A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo 分子名称: FORMIC ACID, Protein humpback-2 著者 Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I. 登録日 2014-08-03 公開日 2015-04-29 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo Dev.Cell, 33, 2015
1QYM	X-ray structure of human gankyrin 分子名称: 26S proteasome non-ATPase regulatory subunit 10 著者 Manjasetty, B.A, Quedenau, C, Sievert, V, Buessow, K, Niesen, F, Delbrueck, H, Heinemann, U. 登録日 2003-09-11 公開日 2003-11-18 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma. Proteins, 55, 2004
4RAU	crystal structure of RTOFab in complex with human PF4 分子名称: Platelet factor 4, RTOFab heavy chain, RTOFab light chain 著者 Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. 登録日 2014-09-11 公開日 2016-03-16 実験手法 X-RAY DIFFRACTION (3.74 Å) 主引用文献 crystal structure of RTOFab in complex with platelet factor 4 To be Published
4QPP	The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421 (2-{4-[3-CHLORO-2-(2-METHOXYPHENYL)-1H-INDOL-5-YL]PIPERIDIN-1-YL}-N-METHYLETHANAMINE 分子名称: 2-{4-[3-chloro-2-(2-methoxyphenyl)-1H-indol-5-yl]piperidin-1-yl}-N-methylethanamine, POLY-UNK, Protein arginine N-methyltransferase 6, ... 著者 Dong, A, Zeng, H, Smil, D, Walker, J.R, He, H, Eram, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Vedadi, M, Brown, P.J, Wu, H, Structural Genomics Consortium (SGC) 登録日 2014-06-24 公開日 2014-08-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 The Crystal Structure of Human HMT1 hnRNP methyltransferase-like protein 6 in complex with compound DS-421 To be Published
3FJK	Crystal structure of A66C mutant of Human acidic fibroblast growth factor 分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION 著者 Blaber, M, Lee, J. 登録日 2008-12-14 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine. J.Mol.Biol., 393, 2009
4RA2	PP2Ca 分子名称: MANGANESE (II) ION, PHOSPHATE ION, Protein phosphatase 1A 著者 Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. 登録日 2014-09-09 公開日 2015-05-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 The catalytic role of the M2 metal ion in PP2Ca SCI REP, 2015
4RBO	Crystal structure of a Nanog homeobox (NANOG) from Homo sapiens at 3.30 A resolution 分子名称: 5'-D(*CP*TP*TP*GP*AP*AP*TP*GP*GP*GP*CP*C)-3', 5'-D(*GP*GP*CP*CP*CP*AP*TP*TP*CP*AP*AP*G)-3', Putative homeobox protein NANOGP8 著者 Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) 登録日 2014-09-12 公開日 2014-10-01 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells. Proc.Natl.Acad.Sci.USA, 112, 2015
4RJ3	CDK2 with EGFR inhibitor compound 8 分子名称: 1-cyclopentyl-N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-1H-pyrrolo[3,2-c]pyridin-6-amine, ACETATE ION, Cyclin-dependent kinase 2 著者 Eigenbrot, C, Yin, J. 登録日 2014-10-08 公開日 2014-11-26 最終更新日 2015-01-14 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Discovery of Selective and Noncovalent Diaminopyrimidine-Based Inhibitors of Epidermal Growth Factor Receptor Containing the T790M Resistance Mutation. J.Med.Chem., 57, 2014
7N7I	X-ray crystal structure of Viperin-like enzyme from Trichoderma virens 分子名称: IRON/SULFUR CLUSTER, S-ADENOSYLMETHIONINE, URIDINE 5'-TRIPHOSPHATE, ... 著者 Grove, T.L, Almo, S.C, Bonanno, J.B, Lachowicz, J.C, Gizzi, A.G. 登録日 2021-06-10 公開日 2021-06-30 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structural Insight into the Substrate Scope of Viperin and Viperin-like Enzymes from Three Domains of Life. Biochemistry, 60, 2021

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