3V6B
| VEGFR-2/VEGF-E complex structure | 分子名称: | VEGF-E, Vascular endothelial growth factor receptor 2 | 著者 | Brozzo, M.S, Leppanen, V.-M, Winkler, F.K, Kisko, K, Ballmer-Hofer, K. | 登録日 | 2011-12-19 | 公開日 | 2012-01-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.205 Å) | 主引用文献 | Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization. Blood, 119, 2012
|
|
3V2A
| VEGFR-2/VEGF-A COMPLEX STRUCTURE | 分子名称: | Vascular endothelial growth factor A, Vascular endothelial growth factor receptor 2 | 著者 | Brozzo, M.S, Leppanen, V.-M, Winkler, F.K, Ballmer-Hofer, K. | 登録日 | 2011-12-12 | 公開日 | 2012-01-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.204 Å) | 主引用文献 | Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization. Blood, 119, 2012
|
|
2FQ0
| Solution structure of major conformation of holo-acyl carrier protein from malaria parasite plasmodium falciparum | 分子名称: | 4'-PHOSPHOPANTETHEINE, acyl carrier protein | 著者 | Sharma, A.K, Sharma, S.K, Surolia, A, Surolia, N, Sarma, S.P. | 登録日 | 2006-01-17 | 公開日 | 2006-08-08 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of conformationally equilibrium forms of holo-acyl carrier protein (PfACP) from Plasmodium falciparum provides insight into the mechanism of activation of ACPs Biochemistry, 45, 2006
|
|
2FVA
| |
2FQ2
| Solution structure of minor conformation of holo-acyl carrier protein from malaria parasite plasmodium falciparum | 分子名称: | 4'-PHOSPHOPANTETHEINE, acyl carrier protein | 著者 | Sharma, A.K, Sharma, S.K, Surolia, A, Surolia, N, Sarma, S.P. | 登録日 | 2006-01-17 | 公開日 | 2006-08-08 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of conformationally equilibrium forms of holo-acyl carrier protein (PfACP) from Plasmodium falciparum provides insight into the mechanism of activation of ACPs Biochemistry, 45, 2006
|
|
1E8D
| MECHANISTIC ASPECTS OF CYANOGENESIS FROM ACTIVE SITE MUTANT SER80ALA OF HYDROXYNITRILE LYASE FROM MANIHOT ESCULENTA IN COMPLEX WITH ACETONE CYANOHYDRIN | 分子名称: | 2-HYDROXY-2-METHYLPROPANENITRILE, HYDROXYNITRILE LYASE | 著者 | Lauble, H, Miehlich, B, Foerster, S, Wajant, H, Effenberger, F. | 登録日 | 2000-09-19 | 公開日 | 2001-08-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanistic Aspects of Cyanogenesis from Active-Site Mutant Ser80Ala of Hydroxynitrile Lyase from Manihot Esculenta in Complex with Acetone Cyanohydrin. Protein Sci., 10, 2001
|
|
2BU5
| crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands | 分子名称: | 4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE, PYRUVATE DEHYDROGENASE KINASE ISOENZYME 2 | 著者 | Knoechel, T.R, Tucker, A.D, Robinson, C.M, Phillips, C, Taylor, W, Bungay, P.J, Kasten, S.A, Roche, T.E, Brown, D.G. | 登録日 | 2005-06-08 | 公開日 | 2006-02-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands. Biochemistry, 45, 2006
|
|
5YG0
| Plasmodium vivax SHMT bound with PLP-glycine and GS657 | 分子名称: | 2-[1-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-(trifluoromethyl)phenyl]piperidin-4-yl]ethanoic acid, CHLORIDE ION, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... | 著者 | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U, Schwertz, G, Diederich, F. | 登録日 | 2017-09-22 | 公開日 | 2018-09-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | to be published to be published
|
|
1FQ4
| CRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(2R)-1-{[(2S,3R,5R)-1-cyclohexyl-3-hydroxy-5-{[2-(morpholin-4-yl)ethyl]carbamoyl}oct-7-yn-2-yl]amino}-3-(methylsulfa nyl)-1-oxopropan-2-yl]-1H-benzimidazole-2-carboxamide, SACCHAROPEPSIN, ... | 著者 | Cronin, N.B, Badasso, M.O, Tickle, I.J, Dreyer, T, Hoover, D.J, Rosati, R.L, Humblet, C.C, Lunney, E.A, Cooper, J.B. | 登録日 | 2000-09-03 | 公開日 | 2000-09-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity. J.Mol.Biol., 303, 2000
|
|
8DJR
| Cytosolic ascorbate peroxidase from Sorghum bicolor | 分子名称: | L-ascorbate peroxidase, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ... | 著者 | Zhang, B, Kang, C. | 登録日 | 2022-07-01 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | A sorghum ascorbate peroxidase with four binding sites has activity against ascorbate and phenylpropanoids. Plant Physiol., 192, 2023
|
|
8DJX
| |
8DJU
| Cytosolic ascorbate peroxidase from Sorghum bicolor - bicyclic dehydroascorbic acid complex | 分子名称: | (3aS,6S,6aR)-3,3,3a,6-tetrahydroxytetrahydrofuro[3,2-b]furan-2(3H)-one (non-preferred name), L-ascorbate peroxidase, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Zhang, B, Kang, C. | 登録日 | 2022-07-01 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | A sorghum ascorbate peroxidase with four binding sites has activity against ascorbate and phenylpropanoids. Plant Physiol., 192, 2023
|
|
8DJW
| |
3FOR
| |
1JAO
| COMPLEX OF 3-MERCAPTO-2-BENZYLPROPANOYL-ALA-GLY-NH2 WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) | 分子名称: | CALCIUM ION, MATRIX METALLO PROTEINASE-8 (MET80 FORM), N-[(2S)-2-benzyl-3-sulfanylpropanoyl]-L-alanylglycinamide, ... | 著者 | Grams, F, Reinemer, P, Powers, J.C, Kleine, T, Piper, M, Tschesche, H, Huber, R, Bode, W. | 登録日 | 1996-03-11 | 公開日 | 1996-07-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design. Eur.J.Biochem., 228, 1995
|
|
5YFY
| Plasmodium vivax SHMT bound with PLP-glycine and GS625 | 分子名称: | 1-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-fluoranyl-phenyl]piperidine-4-carboxylic acid, CHLORIDE ION, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... | 著者 | Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U, Schwertz, G, Diederich, F. | 登録日 | 2017-09-22 | 公開日 | 2018-09-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | to be published to be published
|
|
1FSK
| COMPLEX FORMATION BETWEEN A FAB FRAGMENT OF A MONOCLONAL IGG ANTIBODY AND THE MAJOR ALLERGEN FROM BIRCH POLLEN BET V 1 | 分子名称: | ANTIBODY HEAVY CHAIN FAB, IMMUNOGLOBULIN KAPPA LIGHT CHAIN, MAJOR POLLEN ALLERGEN BET V 1-A | 著者 | Mirza, O, Henriksen, A, Ipsen, H, Larsen, J, Wissenbach, M, Spangfort, M, Gajhede, M. | 登録日 | 2000-09-11 | 公開日 | 2000-10-02 | 最終更新日 | 2018-03-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Dominant epitopes and allergic cross-reactivity: complex formation between a Fab fragment of a monoclonal murine IgG antibody and the major allergen from birch pollen Bet v 1. J.Immunol., 165, 2000
|
|
1FQ8
| X-RAY STRUCTURE OF DIFLUOROSTATINE INHIBITOR CP81,198 BOUND TO SACCHAROPEPSIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-cyclohexyl-4,4-difluoro-3-hydroxy-5-(methylamino)-5-oxo-pentan-2-yl]amino]-1-oxo-hexan-2 -yl]amino]-1-oxo-3-phenyl-propan-2-yl]morpholine-4-carboxamide, SACCHAROPEPSIN, ... | 著者 | Cronin, N.B, Badasso, M.O, Tickle, I.J, Dreyer, T, Hoover, D.J, Rosati, R.L, Humblet, C.C, Lunney, E.A, Cooper, J.B. | 登録日 | 2000-09-04 | 公開日 | 2000-09-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity. J.Mol.Biol., 303, 2000
|
|
1FNT
| CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST IN COMPLEX WITH THE PROTEASOME ACTIVATOR PA26 FROM TRYPANOSOME BRUCEI AT 3.2 ANGSTROMS RESOLUTION | 分子名称: | MAGNESIUM ION, PROTEASOME ACTIVATOR PROTEIN PA26, PROTEASOME COMPONENT C1, ... | 著者 | Whitby, F.G, Masters, E, Kramer, L, Knowlton, J.R, Yao, Y, Wang, C.C, Hill, C.P. | 登録日 | 2000-08-23 | 公開日 | 2001-04-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the activation of 20S proteasomes by 11S regulators. Nature, 408, 2000
|
|
8DNK
| |
6ZW9
| [4Fe-4S]-dependent thiouracil desulfidase TudS (DUF523Vcz) soaked with 4-thiouracil (S-SAD data) | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DUF523 domain-containing protein, ... | 著者 | Pecqueur, L, Zhou, J, Fontecave, M, Golinelli-Pimpaneau, B. | 登録日 | 2020-07-28 | 公開日 | 2020-09-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.759 Å) | 主引用文献 | Structural Evidence for a [4Fe-5S] Intermediate in the Non-Redox Desulfuration of Thiouracil. Angew.Chem.Int.Ed.Engl., 60, 2021
|
|
1N86
| Crystal structure of human D-dimer from cross-linked fibrin complexed with GPR and GHRPLDK peptide ligands. | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, CALCIUM ION, Fibrin alpha/alpha-E chain, ... | 著者 | Yang, Z, Pandi, L, Doolittle, R.F. | 登録日 | 2002-11-19 | 公開日 | 2003-01-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface. Biochemistry, 41, 2002
|
|
8DNI
| |
5K6S
| The structure of the PP2A B56 subunit BubR1 complex | 分子名称: | BubR1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | 著者 | Page, R, Wang, X, Bajaj, R, Peti, W. | 登録日 | 2016-05-25 | 公開日 | 2016-12-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | 主引用文献 | Expanding the PP2A Interactome by Defining a B56-Specific SLiM. Structure, 24, 2016
|
|
1I5I
| THE C18S MUTANT OF BOVINE (GAMMA-B)-CRYSTALLIN | 分子名称: | (GAMMA-B) CRYSTALLIN | 著者 | Zarutskie, J.A, Asherie, N, Pande, J, Pande, A, Lomakin, J, Lomakin, A, Ogun, O, Stern, L.J, King, J.A, Benedek, G.B. | 登録日 | 2001-02-27 | 公開日 | 2001-03-07 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Enhanced crystallization of the Cys18 to Ser mutant of bovine gammaB crystallin. J.Mol.Biol., 314, 2001
|
|