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6W1N
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BU of 6w1n by Molmil
Pig Ryanodine Receptor (WT) in 5mM EGTA condition
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ZINC ION
著者Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
登録日2020-03-04
公開日2021-01-06
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6VJ4
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BU of 6vj4 by Molmil
1.70 Angstrom Resolution Crystal Structure of Peptidylprolyl Isomerase (PrsA) from Bacillus anthracis
分子名称: Peptidylprolyl isomerase PrsA
著者Minasov, G, Shuvalova, L, Kiryukhina, O, Wiersum, G, Endres, M, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-01-14
公開日2020-02-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献1.70 Angstrom Resolution Crystal Structure of Peptidylprolyl Isomerase (PrsA) from Bacillus anthracis
To Be Published
3BTV
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BU of 3btv by Molmil
Crystal structure of the super-repressor mutant of Gal80p from Saccharomyces cerevisiae; Gal80(S0)-[G301R]
分子名称: Galactose/lactose metabolism regulatory protein GAL80
著者Kumar, P.R, Joshua-Tor, L.
登録日2007-12-31
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献NADP regulates the yeast GAL induction system.
Science, 319, 2008
6VJ2
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BU of 6vj2 by Molmil
3.10 Angstrom Resolution Crystal Structure of Foldase Protein (PrsA) from Lactococcus lactis
分子名称: Foldase
著者Minasov, G, Shuvalova, L, Kiryukhina, O, Endres, M, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-01-14
公開日2020-02-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献3.10 Angstrom Resolution Crystal Structure of Foldase Protein (PrsA) from Lactococcus lactis
To Be Published
5XS2
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BU of 5xs2 by Molmil
CDK8-CYCC IN COMPLEX WITH COMPOUND 17:3-chloro-4-(4-pyridyl)-1H-pyrrole-2-carboxamide
分子名称: 3-chloranyl-4-pyridin-4-yl-1H-pyrrole-2-carboxamide, Cyclin-C, Cyclin-dependent kinase 8, ...
著者Zhou, Z, Xu, Z.
登録日2017-06-12
公開日2017-08-09
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Discovery of potent and selective CDK8 inhibitors through FBDD approach
Bioorg. Med. Chem. Lett., 27, 2017
6VRX
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BU of 6vrx by Molmil
Mucor circinelloides FKBP12 protein bound with FK506 in P3221 space group
分子名称: 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN, Peptidylprolyl isomerase
著者Gobeil, S, Spicer, L.
登録日2020-02-10
公開日2020-12-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs.
Mbio, 12, 2021
5BWM
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BU of 5bwm by Molmil
The complex structure of C3cer exoenzyme and GDP bound RhoA (NADH-bound state)
分子名称: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ADP-ribosyltransferase, ...
著者Toda, A, Tsurumura, T, Yoshida, T, Tsuge, H.
登録日2015-06-08
公開日2015-06-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure.
J.Biol.Chem., 290, 2015
1W74
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BU of 1w74 by Molmil
X-ray structure of peptidyl-prolyl cis-trans isomerase A, PpiA, Rv0009, from Mycobacterium tuberculosis.
分子名称: PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Henriksson, L.M, Johansson, P, Unge, T, Mowbray, S.L.
登録日2004-08-27
公開日2004-10-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献X-Ray Structure of Peptidyl-Prolyl Cis-Trans Isomerase a from Mycobacterium Tuberculosis
Eur.J.Biochem., 271, 2004
3DLK
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BU of 3dlk by Molmil
Crystal Structure of an engineered form of the HIV-1 Reverse Transcriptase, RT69A
分子名称: Reverse transcriptase/ribonuclease H, SULFATE ION, p51 RT
著者Ho, W.C, Bauman, J.D, Himmel, D.M, Das, K, Arnold, E.
登録日2008-06-27
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design.
Nucleic Acids Res., 36, 2008
6VZG
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BU of 6vzg by Molmil
Cryo-EM structure of Sth1-Arp7-Arp9-Rtt102
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-like protein ARP9, Actin-related protein 7, ...
著者Leschziner, A.E, Baker, R.W.
登録日2020-02-28
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insights into assembly and function of the RSC chromatin remodeling complex.
Nat.Struct.Mol.Biol., 28, 2021
4TRX
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BU of 4trx by Molmil
HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF REDUCED RECOMBINANT HUMAN THIOREDOXIN IN SOLUTION
分子名称: THIOREDOXIN
著者Forman-Kay, J.D, Clore, G.M, Gronenborn, A.M.
登録日1990-12-17
公開日1992-01-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution.
Biochemistry, 30, 1991
5VHM
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BU of 5vhm by Molmil
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
分子名称: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ...
著者Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y.
登録日2017-04-13
公開日2017-08-23
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (8.3 Å)
主引用文献Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.
Mol. Cell, 67, 2017
1RR7
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BU of 1rr7 by Molmil
Crystal structure of the Middle Operon Regulator protein of Bacteriophage Mu
分子名称: Middle operon regulator, PLATINUM (II) ION
著者Kumaraswami, M, Howe, M.M, Park, H.W.
登録日2003-12-08
公開日2004-08-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the Mor protein of bacteriophage Mu, a member of the Mor/C family of transcription activators.
J.Biol.Chem., 279, 2004
3PRB
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BU of 3prb by Molmil
Structural analysis of protein folding by the Methanococcus jannaschii chaperone FKBP26
分子名称: FKBP-type peptidyl-prolyl cis-trans isomerase
著者Martinez-Hackert, E, Hendrickson, W.A.
登録日2010-11-29
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26.
J.Mol.Biol., 407, 2011
3BTU
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BU of 3btu by Molmil
Crystal structure of the super-repressor mutant of Gal80p from Saccharomyces cerevisiae; Gal80(S2) [E351K]
分子名称: Galactose/lactose metabolism regulatory protein GAL80
著者Kumar, P.R, Joshua-Tor, L.
登録日2007-12-30
公開日2008-03-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献NADP regulates the yeast GAL induction system.
Science, 319, 2008
3ODK
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BU of 3odk by Molmil
Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3-pyridin-2-yl-1H-pyrazole-5-carboxylic acid, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Potter, A, Oldfield, V, Nunns, C, Fromont, C, Ray, S, Northfield, C.J, Bryant, C.J, Scrace, S.F, Robinson, D, Matossova, N, Baker, L, Dokurno, P, Surgenor, A.E, Davis, B.E, Richardson, C.M, Murray, J.B, Moore, J.D.
登録日2010-08-11
公開日2010-10-27
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution.
Bioorg.Med.Chem.Lett., 20, 2010
3PRD
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BU of 3prd by Molmil
Structural analysis of protein folding by the Methanococcus jannaschii chaperone FKBP26
分子名称: FKBP-type peptidyl-prolyl cis-trans isomerase
著者Martinez-Hackert, E, Hendrickson, W.A.
登録日2010-11-29
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Analysis of Protein Folding by the Long-Chain Archaeal Chaperone FKBP26.
J.Mol.Biol., 407, 2011
2JNJ
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BU of 2jnj by Molmil
Solution structure of the p8 TFIIH subunit
分子名称: TFIIH basal transcription factor complex TTD-A subunit
著者Vitorino, M, Atkinson, R.A, Moras, D, Poterszman, A, Kieffer, B, Structural Proteomics in Europe 2 (SPINE-2)
登録日2007-01-26
公開日2007-04-10
最終更新日2023-12-20
実験手法SOLUTION NMR
主引用文献Solution Structure and Self-association Properties of the p8 TFIIH Subunit Responsible for Trichothiodystrophy
J.Mol.Biol., 368, 2007
4MM2
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BU of 4mm2 by Molmil
Crystal structure of yeast primase catalytic subunit
分子名称: CADMIUM ION, CITRIC ACID, DNA primase small subunit
著者Park, K.R, An, J.Y, Lee, Y, Youn, H.S, Lee, J.G, Kang, J.Y, Kim, T.G, Lim, J.J, Eom, S.H, Wang, J.
登録日2013-09-07
公開日2014-09-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of yeast primase catalytic subunit
To be Published
3PMP
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BU of 3pmp by Molmil
Crystal Structure of Cyclophilin A from Moniliophthora perniciosa in complex with Cyclosporin A
分子名称: CYCLOSPORIN A, Cyclophilin A
著者Monzani, P, Pereira, H.M, Gramacho, K.P, Meirelles, F.V, Oliva, G, Cascardo, J.C.C.
登録日2010-11-17
公開日2011-11-23
最終更新日2023-05-31
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Crystal Structure of Cyclophilin A from Moniliophthora perniciosa
To be Published
3O7T
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BU of 3o7t by Molmil
Crystal Structure of Cyclophilin A from Moniliophthora perniciosa
分子名称: Cyclophilin A
著者Monzani, P.S, Pereira, H.M, Gramacho, K.P, Meirelles, F.V, Oliva, G, Cascardo, J.C.M.
登録日2010-07-31
公開日2011-08-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structures of apo-cyclophilin and bounded cyclosporine A from Moniliophthora perniciosa
To be Published
2IZV
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BU of 2izv by Molmil
CRYSTAL STRUCTURE OF SOCS-4 IN COMPLEX WITH ELONGIN-B AND ELONGIN-C AT 2.55A RESOLUTION
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ...
著者Debreczeni, J.E, Bullock, A, Papagrigoriou, E, Turnbull, A, Pike, A.C.W, Gorrec, F, von Delft, F, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Knapp, S.
登録日2006-07-26
公開日2006-08-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.
Structure, 15, 2007
5L6Y
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BU of 5l6y by Molmil
il13 in complex with tralokinumab
分子名称: FORMIC ACID, Interleukin-13, tralokinumab FAb digest VH, ...
著者Breed, J.
登録日2016-06-01
公開日2016-12-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13R alpha 1 and IL-13R alpha 2.
J. Mol. Biol., 429, 2017
8P3C
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BU of 8p3c by Molmil
Full length structure of BpMIP with bound inhibitor NJS227.
分子名称: (2~{S})-1-[(4-fluorophenyl)methylsulfonyl]-~{N}-[(2~{S})-3-(4-fluorophenyl)-1-oxidanylidene-1-(pyridin-3-ylmethylamino)propan-2-yl]piperidine-2-carboxamide, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Whittaker, J.J, Guskov, A, Goretzki, B, Hellmich, U.A.
登録日2023-05-17
公開日2024-06-12
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural dynamics of macrophage infectivity potentiator proteins (MIPs) are differentially modulated by inhibitors and appendage domains
To Be Published
8P3D
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BU of 8p3d by Molmil
Full length structure of TcMIP with bound inhibitor NJS224.
分子名称: (2~{S})-1-[(4-fluorophenyl)methylsulfonyl]-~{N}-[(2~{S})-4-methyl-1-oxidanylidene-1-(pyridin-3-ylmethylamino)pentan-2-yl]piperidine-2-carboxamide, SODIUM ION, peptidylprolyl isomerase
著者Whittaker, J.J, Guskov, A, Goretzki, B, Hellmich, U.A.
登録日2023-05-17
公開日2024-06-12
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structural dynamics of macrophage infectivity potentiator proteins (MIPs) are differentially modulated by inhibitors and appendage domains
To Be Published

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